Table 5. Outcomes by treatment cohort... | American Society of Hematology

Table 5.

Outcomes by treatment cohort and number of prior lines of therapy

Outcomes	Alternate	CAR T	P
2 prior lines
Total, n	146	32
CR rate, %	22	56	<.001
ORR, %	32	75	<.001
Median OS, mo	6.5	19.3	.02
Median PFS, mo	2.3	6.4	.04
3 prior lines
Total, n	59	23
CR rate, %	8.6	52	<.001
ORR, %	16	74	<.001
Median OS, mo	4.7	Not reached	.001
Median PFS, mo	1.7	12.3	<.001
4 prior lines
Total, n	26	14
CR rate, %	8	43	.02
ORR, %	8	64	<.001
Median OS, mo	2.9	7.0	.03
Median PFS, mo	1.4	3.0	.008

Outcomes	Alternate	CAR T	P
2 prior lines
Total, n	146	32
CR rate, %	22	56	<.001
ORR, %	32	75	<.001
Median OS, mo	6.5	19.3	.02
Median PFS, mo	2.3	6.4	.04
3 prior lines
Total, n	59	23
CR rate, %	8.6	52	<.001
ORR, %	16	74	<.001
Median OS, mo	4.7	Not reached	.001
Median PFS, mo	1.7	12.3	<.001
4 prior lines
Total, n	26	14
CR rate, %	8	43	.02
ORR, %	8	64	<.001
Median OS, mo	2.9	7.0	.03
Median PFS, mo	1.4	3.0	.008

P values in bold are statistically significant.