Populations of bone marrow cells or Lin– of wild-type, IL-6–/–, SHIP–/–, and IL-6–/– SHIP–/– mice
. | Wild-type . | IL-6-/- . | SHIP-/- . | SHIP-/- IL-6-/- . |
|---|---|---|---|---|
| Bone marrow cells, × 106 | ||||
| CD19+ | 58 ± 19 | 35 ± 11 | 3 ± 2 | 18 ± 9 |
| Mac-1+ | 56 ± 18 | 51 ± 10 | 78 ± 12 | 78 ± 6 |
| CD3+ | 3 ± 2 | 4 ± 1 | 1 ± 0.5 | 1.5 ± 0.5 |
| Lin-, × 106 | 2 ± 0.5 | 2 ± 0.1 | 2 ± 0.5 | 2 ± 0.4 |
| c-KithiSca-1+, × 104 | 24 ± 10 | 19 ± 3 | 21 ± 2 | 45 ± 4 |
| c-KitloSca-1lo IL7R+, × 104 | 5 ± 1 | 5 ± 1 | 0.3 ± 0.02 | 4 ± 1 |
. | Wild-type . | IL-6-/- . | SHIP-/- . | SHIP-/- IL-6-/- . |
|---|---|---|---|---|
| Bone marrow cells, × 106 | ||||
| CD19+ | 58 ± 19 | 35 ± 11 | 3 ± 2 | 18 ± 9 |
| Mac-1+ | 56 ± 18 | 51 ± 10 | 78 ± 12 | 78 ± 6 |
| CD3+ | 3 ± 2 | 4 ± 1 | 1 ± 0.5 | 1.5 ± 0.5 |
| Lin-, × 106 | 2 ± 0.5 | 2 ± 0.1 | 2 ± 0.5 | 2 ± 0.4 |
| c-KithiSca-1+, × 104 | 24 ± 10 | 19 ± 3 | 21 ± 2 | 45 ± 4 |
| c-KitloSca-1lo IL7R+, × 104 | 5 ± 1 | 5 ± 1 | 0.3 ± 0.02 | 4 ± 1 |
Each population in the total bone marrow cells was analyzed by flow cytometry (see “Materials and methods”). The data were obtained from five 4-week-old mice and are shown as average number per mouse and SE.