Gain of telomeric pairs per population doubling, HK1-hTERT
. | Telomere length . | . | No. population doublings . | . | . | ||
|---|---|---|---|---|---|---|---|
. | 84 d in culture . | 105 d in culture . | 84 d in culture . | 105 d in culture . | bp gain per PD . | ||
| Negative control | 11.1 | 14.0 | 37.1 | 46.0 | + 344 | ||
| DMSO | 11.3 | 13.8 | 36.0 | 45.1 | + 280 | ||
| BIBR1532 | |||||||
| 10 μM | 10.7 | 11.7 | 35.3 | 44.5 | + 110 | ||
| 30 μM | 9.7 | 10.4 | 35.0 | 44.5 | + 76 | ||
| 50 μM | 9.4 | 9.6 | 33.6 | 42.1 | + 32 | ||
. | Telomere length . | . | No. population doublings . | . | . | ||
|---|---|---|---|---|---|---|---|
. | 84 d in culture . | 105 d in culture . | 84 d in culture . | 105 d in culture . | bp gain per PD . | ||
| Negative control | 11.1 | 14.0 | 37.1 | 46.0 | + 344 | ||
| DMSO | 11.3 | 13.8 | 36.0 | 45.1 | + 280 | ||
| BIBR1532 | |||||||
| 10 μM | 10.7 | 11.7 | 35.3 | 44.5 | + 110 | ||
| 30 μM | 9.7 | 10.4 | 35.0 | 44.5 | + 76 | ||
| 50 μM | 9.4 | 9.6 | 33.6 | 42.1 | + 32 | ||