Table 2. Annexin V analysis of apoptotic... | American Society of Hematology

Table 2.

Annexin V analysis of apoptotic responses in 15 AML patients

Patient no.	Incubation time, h	AS602868, 10 μM, %	VP16, 10 μM, %	AS602868, 10 μM; VP16, 10 μM, %	IC₅₀, μM; AS602868
1	72	87	1	89	4
2	72	73	7	93	1.4
3	72	63	–16	75	2.2
4	72	71	64	78	1
5	48	45	85	94	14
6	72	34	16	59	14
7	72	17	79	86	> 30
8	72	78	28	87	2.8
9	72	92	58	97	0.6
10	72	92	ND	ND	2.8
11	72	39	31	66	5
12	72	36	39	44	> 30
13	72	65	1	79	8
14	72	64	77	87	7.1
15	72	23	60	77	> 30

Patient no.	Incubation time, h	AS602868, 10 μM, %	VP16, 10 μM, %	AS602868, 10 μM; VP16, 10 μM, %	IC₅₀, μM; AS602868
1	72	87	1	89	4
2	72	73	7	93	1.4
3	72	63	–16	75	2.2
4	72	71	64	78	1
5	48	45	85	94	14
6	72	34	16	59	14
7	72	17	79	86	> 30
8	72	78	28	87	2.8
9	72	92	58	97	0.6
10	72	92	ND	ND	2.8
11	72	39	31	66	5
12	72	36	39	44	> 30
13	72	65	1	79	8
14	72	64	77	87	7.1
15	72	23	60	77	> 30

Statistical analysis by paired ANOVA and PLSD Fisher test (a probability of < .05 is considered significant).

ND indicates not determined.