Biologic response marker genes for IFN and ISS activity
. | . | Induced in vitro . | . | . | |
|---|---|---|---|---|---|
| Symbol . | Name . | IFN-α . | IFN-γ . | Induced in patients ISS . | |
| 2′-5′ OAS | 2′-5-Oligoadenylate synthetase | + | - | + | |
| ISG-54 | Interferon-stimulated gene, 54 kDa | + | - | + | |
| MxB | Myxoma resistance-B | + | - | + | |
| MCP-1 | Monocyte chemotactic protein | + | + | + | |
| MCP-2 | Monocyte chemotactic protein | + | + | + | |
| IP-10 | IFN-γ—inducible protein 10 | + | + | + | |
| IRF-1 | Interferon-responsive factor-1 | - | + | - | |
| MIG | Monokine induced by IFN-γ | - | + | - | |
. | . | Induced in vitro . | . | . | |
|---|---|---|---|---|---|
| Symbol . | Name . | IFN-α . | IFN-γ . | Induced in patients ISS . | |
| 2′-5′ OAS | 2′-5-Oligoadenylate synthetase | + | - | + | |
| ISG-54 | Interferon-stimulated gene, 54 kDa | + | - | + | |
| MxB | Myxoma resistance-B | + | - | + | |
| MCP-1 | Monocyte chemotactic protein | + | + | + | |
| MCP-2 | Monocyte chemotactic protein | + | + | + | |
| IP-10 | IFN-γ—inducible protein 10 | + | + | + | |
| IRF-1 | Interferon-responsive factor-1 | - | + | - | |
| MIG | Monokine induced by IFN-γ | - | + | - | |
+ Indicates that gene was induced.
- Indicates that gene was not induced.