Table 1. Experimental design Serotype .... | American Society of Hematology

Table 1.

Experimental design

Serotype	Route of administration/vector form	No. of mice tested
	Intraportal
8	2 chains	32
8	Single chain	15
7	2 chains	21
5	2 chains	16
2	2 chains	21
2	Single chain	15
	Tail vein
8	2 chains	3
8	Single chain	4
2	Single chain	4

Serotype	Route of administration/vector form	No. of mice tested
	Intraportal
8	2 chains	32
8	Single chain	15
7	2 chains	21
5	2 chains	16
2	2 chains	21
2	Single chain	15
	Tail vein
8	2 chains	3
8	Single chain	4
2	Single chain	4

AAV vector administration into FVII KO mice. Serotypes 2, 5, 7, and 8 expressing B domain-deleted canine FVIII cDNA were evaluated in hemophilia A mice. Details of the total number of mice tested, routes of vector administration, and numbers of mice receiving FVIII either in 2 vectors (heavy and light chain) or as a single-chain vector are listed.

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