Table 4.

Prognostic factors for complete remission

N
CR, %
P
Age younger than 46 y   247   83.8   .09  
Age older than 45 y   178   77   
FAB 2 and 4   225   84.9   
FAB other   200   76.5   .04  
Performance status less than 3   327   84.4   .001  
Performance status higher than 2   97   69.0   
WBC count lower than 30 × 109/L   281   86.5   < .0001  
WBC count higher than 30 × 109/L   144   75.4   
Karyotype     < .0001  
    Normal   180   82.2   
    Good   64   96.9   
    Intermediate   61   67.2   
    Poor   59   69.5   
Rh123 efflux positive   54   65.4   .04  
Rh123 efflux negative   106   81.3   
mdr gene positive   76   82.9   NS  
mdr gene negative   188   83.8   
UIC2 positive   77   80.6   NS  
UIC2 negative   160   78.8   
4E3 positive   62   83.7   NS  
4E3 negative   169   76.3   
Quinine dose reduction   79   80.2   NS
 
No quinine dose reduction
 		 134
 		 81.8
 		 
N
CR, %
P
Age younger than 46 y   247   83.8   .09  
Age older than 45 y   178   77   
FAB 2 and 4   225   84.9   
FAB other   200   76.5   .04  
Performance status less than 3   327   84.4   .001  
Performance status higher than 2   97   69.0   
WBC count lower than 30 × 109/L   281   86.5   < .0001  
WBC count higher than 30 × 109/L   144   75.4   
Karyotype     < .0001  
    Normal   180   82.2   
    Good   64   96.9   
    Intermediate   61   67.2   
    Poor   59   69.5   
Rh123 efflux positive   54   65.4   .04  
Rh123 efflux negative   106   81.3   
mdr gene positive   76   82.9   NS  
mdr gene negative   188   83.8   
UIC2 positive   77   80.6   NS  
UIC2 negative   160   78.8   
4E3 positive   62   83.7   NS  
4E3 negative   169   76.3   
Quinine dose reduction   79   80.2   NS
 
No quinine dose reduction
 		 134
 		 81.8
 		 

NS indicates not significant.

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