Table 4. Comparison of the clinical and... | American Society of Hematology

Table 4.

Comparison of the clinical and laboratory data among the three genetic subgroups

Parameter	17p−	V_H ≥97%	V_H<97%	P
No. patients	20	170	110
Median age, y	64	63	61	.12^4-151
Male sex, %	75	60	59	.41^‡
Stage, %
Binet A	25	43	71	<.001^‡
Binet B	40	37	23
Binet C	35	20	6
Rai 0	0	14	33	<.001^‡
Rai 1	5	16	13
Rai 2	45	45	48
Rai 3	20	13	4
Rai 4	30	12	4
White blood count, ×10⁹/L	52.3	39.3	26.8	.02^4-151
Hemoglobin, g/L	125	131	136	.001^4-151
Platelet count, ×10⁹/L	148	171	188	.004^4-151
Lactate dehydrogenase, IU/L	250	180	156	<.001^4-151
Alkaline phosphatase, IU/L	159	127	117	.003^4-151
Albumin, g/L	43	45	46	.10^4-151
Splenomegaly, %	89	67	54	.003^‡^4-150
Mediastinal lymphadenopathy, %	25	12	0	<.001^‡
Abdominal lymphadenopathy, %	65	61	27	<.001^‡
Peripheral lymphadenopathy, cm²^4-150	11	4	0	<.001^4-151
Largest lymph node diameter, cm	3	2.85	1	<.001^4-151
B symptoms, %	37	20	8	.001^‡
Time from diagnosis to first treatment, mo	3.5	33	105	<.001^4-153

Parameter	17p−	V_H ≥97%	V_H<97%	P
No. patients	20	170	110
Median age, y	64	63	61	.12^4-151
Male sex, %	75	60	59	.41^‡
Stage, %
Binet A	25	43	71	<.001^‡
Binet B	40	37	23
Binet C	35	20	6
Rai 0	0	14	33	<.001^‡
Rai 1	5	16	13
Rai 2	45	45	48
Rai 3	20	13	4
Rai 4	30	12	4
White blood count, ×10⁹/L	52.3	39.3	26.8	.02^4-151
Hemoglobin, g/L	125	131	136	.001^4-151
Platelet count, ×10⁹/L	148	171	188	.004^4-151
Lactate dehydrogenase, IU/L	250	180	156	<.001^4-151
Alkaline phosphatase, IU/L	159	127	117	.003^4-151
Albumin, g/L	43	45	46	.10^4-151
Splenomegaly, %	89	67	54	.003^‡^4-150
Mediastinal lymphadenopathy, %	25	12	0	<.001^‡
Abdominal lymphadenopathy, %	65	61	27	<.001^‡
Peripheral lymphadenopathy, cm²^4-150	11	4	0	<.001^4-151
Largest lymph node diameter, cm	3	2.85	1	<.001^4-151
B symptoms, %	37	20	8	.001^‡
Time from diagnosis to first treatment, mo	3.5	33	105	<.001^4-153

All values correspond to the time of enrollment.

Median sum of the products of the diameters of the largest cervical, axillary, and inguinal lymph nodes.

Median values are given for quantitative variables:

Kruskal-Wallis test; ‡Fisher exact test;

log-rank test.