Cytogenetic subgroup comparisons in patients with and without trisomy 8*
| . | With trisomy 8 . | Without trisomy 8 . | P . | ||||
|---|---|---|---|---|---|---|---|
| Median . | Range . | N . | Median . | Range . | N . | ||
| Peripheral blasts (%) | |||||||
| Favorable | 11 | 0-79 | 22 | 31% | 0%-97% | 140 | .048 |
| Intermediate | 10 | 0-95 | 47 | 35% | 0%-99% | 313 | .0088 |
| Unfavorable | 11 | 0-99 | 34 | 24% | 0%-99% | 225 | .27 |
| WBC (1000/mm3) | |||||||
| Favorable | 4.7 | 0.8-60.6 | 23 | 7.3 | 0.5-206.4 | 150 | .55 |
| Intermediate | 7.4 | 1.1-104.6 | 50 | 19.7 | 0.3-274.0 | 330 | .0061 |
| Unfavorable | 6.2 | 0.8-271.2 | 34 | 8.3 | 0.6-230.0 | 234 | .64 |
| Age (y) | |||||||
| Favorable | 50 | 20-71 | 23 | 41 | 16-81 | 153 | .16 |
| Intermediate | 62 | 21-81 | 50 | 60 | 16-84 | 333 | .50 |
| Unfavorable | 64 | 23-83 | 35 | 62 | 15-88 | 235 | .019 |
| . | With trisomy 8 . | Without trisomy 8 . | P . | ||||
|---|---|---|---|---|---|---|---|
| Median . | Range . | N . | Median . | Range . | N . | ||
| Peripheral blasts (%) | |||||||
| Favorable | 11 | 0-79 | 22 | 31% | 0%-97% | 140 | .048 |
| Intermediate | 10 | 0-95 | 47 | 35% | 0%-99% | 313 | .0088 |
| Unfavorable | 11 | 0-99 | 34 | 24% | 0%-99% | 225 | .27 |
| WBC (1000/mm3) | |||||||
| Favorable | 4.7 | 0.8-60.6 | 23 | 7.3 | 0.5-206.4 | 150 | .55 |
| Intermediate | 7.4 | 1.1-104.6 | 50 | 19.7 | 0.3-274.0 | 330 | .0061 |
| Unfavorable | 6.2 | 0.8-271.2 | 34 | 8.3 | 0.6-230.0 | 234 | .64 |
| Age (y) | |||||||
| Favorable | 50 | 20-71 | 23 | 41 | 16-81 | 153 | .16 |
| Intermediate | 62 | 21-81 | 50 | 60 | 16-84 | 333 | .50 |
| Unfavorable | 64 | 23-83 | 35 | 62 | 15-88 | 235 | .019 |
Comparisons that reached statistical significance in any of the risk group categories are included regardless of whether the risk group/+ 8 interaction was statistically significant.