Response to and toxicity of induction therapy
| Characteristic . | Induction regimen . | |
|---|---|---|
| VAD-P (n = 126)* . | VAD-P/Q (n = 124)* . | |
| Response to induction therapy | ||
| R (75%-100% reduction) | 47 (38%) | 49 (40%) |
| PR (50%-74% reduction) | 23 (18%) | 21 (17%) |
| UR | 9 (7%) | 10 (8%) |
| SD | 27 (22%) | 15 (12%) |
| PD | 6 (5%) | 7 (6%) |
| Early death | 1 (1%) | 1 (1%) |
| Inadequate assessment | 12 (10%) | 20 (16%) |
| Total | 125 (100%) | 123 (100%) |
| Maximum grade any toxicity | ||
| At most Grade 2 | 40 | 28 |
| Grades 3-5 | 84 | 95 |
| Characteristic . | Induction regimen . | |
|---|---|---|
| VAD-P (n = 126)* . | VAD-P/Q (n = 124)* . | |
| Response to induction therapy | ||
| R (75%-100% reduction) | 47 (38%) | 49 (40%) |
| PR (50%-74% reduction) | 23 (18%) | 21 (17%) |
| UR | 9 (7%) | 10 (8%) |
| SD | 27 (22%) | 15 (12%) |
| PD | 6 (5%) | 7 (6%) |
| Early death | 1 (1%) | 1 (1%) |
| Inadequate assessment | 12 (10%) | 20 (16%) |
| Total | 125 (100%) | 123 (100%) |
| Maximum grade any toxicity | ||
| At most Grade 2 | 40 | 28 |
| Grades 3-5 | 84 | 95 |
R indicates remission; PR, partial remission; UR, unconfirmed remission; SD, stable disease; PD, progressive disease. See Table 1 for other abbreviations.
One patient in each arm had incomplete response data available.