Patient characteristics at study entry
| Characteristic . | Initial registration . | FAMP therapy . | |||
|---|---|---|---|---|---|
| All patients, % (n = 231) . | Observation longer than 1 y, % (n = 54) . | Overall, % (n = 182) . | No prior therapy, % (n = 118) . | Prior therapy, % (n = 64) . | |
| Age at least 70 y | 35 | 43 | 33 | 29 | 41 |
| Men | 59 | 63 | 58 | 58 | 56 |
| Performance status greater than 1 | 8 | 4* | 9 | 7 | 13 |
| Disease duration longer than 1 y | 34 | 25 | 39 | 19 | 76† |
| Fatigue | 56 | 13* | 70 | 68 | 75 |
| Dizziness | 16 | 0* | 21 | 21 | 21 |
| Visual disturbance | 12 | 2* | 14 | 13 | 16 |
| Bleeding | 19 | 4* | 24 | 27 | 17 |
| Infection | 5 | 2 | 5 | 5 | 5 |
| Lymphadenopathy | 19 | 4* | 24 | 30 | 14† |
| Hepatomegaly | 8 | 0* | 10 | 12 | 6 |
| Splenomegaly | 17 | 2* | 22 | 26 | 14 |
| Characteristic . | Initial registration . | FAMP therapy . | |||
|---|---|---|---|---|---|
| All patients, % (n = 231) . | Observation longer than 1 y, % (n = 54) . | Overall, % (n = 182) . | No prior therapy, % (n = 118) . | Prior therapy, % (n = 64) . | |
| Age at least 70 y | 35 | 43 | 33 | 29 | 41 |
| Men | 59 | 63 | 58 | 58 | 56 |
| Performance status greater than 1 | 8 | 4* | 9 | 7 | 13 |
| Disease duration longer than 1 y | 34 | 25 | 39 | 19 | 76† |
| Fatigue | 56 | 13* | 70 | 68 | 75 |
| Dizziness | 16 | 0* | 21 | 21 | 21 |
| Visual disturbance | 12 | 2* | 14 | 13 | 16 |
| Bleeding | 19 | 4* | 24 | 27 | 17 |
| Infection | 5 | 2 | 5 | 5 | 5 |
| Lymphadenopathy | 19 | 4* | 24 | 30 | 14† |
| Hepatomegaly | 8 | 0* | 10 | 12 | 6 |
| Splenomegaly | 17 | 2* | 22 | 26 | 14 |