Treatment-related toxicity during the initial course of therapy (41 patients, 161 rituximab doses)
| Toxicity . | Number of Patients (%) . | |
|---|---|---|
| Grade 1/2 . | 3/4 . | |
| Infusion-related | ||
| Fever | 9 (22%) | 0 |
| Chills/rigors | 12 (29%) | 0 |
| Flushing | 4 (10%) | 1 (2%) |
| Nausea/vomiting | 5 (12%) | 0 |
| Hypotension | 1 (2%) | 0 |
| Angioedema | 1 (2%) | 0 |
| Bronchospasm | 1 (2%) | 0 |
| Chest pain/cardiac ischemia | 0 | 1 (2%) |
| Other toxicity | ||
| Fatigue | 11 (27%) | 0 |
| Leukopenia | 2 (5%) | 0 |
| Anemia | 3 (7%) | 0 |
| Toxicity . | Number of Patients (%) . | |
|---|---|---|
| Grade 1/2 . | 3/4 . | |
| Infusion-related | ||
| Fever | 9 (22%) | 0 |
| Chills/rigors | 12 (29%) | 0 |
| Flushing | 4 (10%) | 1 (2%) |
| Nausea/vomiting | 5 (12%) | 0 |
| Hypotension | 1 (2%) | 0 |
| Angioedema | 1 (2%) | 0 |
| Bronchospasm | 1 (2%) | 0 |
| Chest pain/cardiac ischemia | 0 | 1 (2%) |
| Other toxicity | ||
| Fatigue | 11 (27%) | 0 |
| Leukopenia | 2 (5%) | 0 |
| Anemia | 3 (7%) | 0 |