Univariate and multivariate analysis of survival (SV)
| Factor . | Univariate P-value . | Multivariate P-value . | ||
|---|---|---|---|---|
| Not Stratif. . | Stratified4-150 . | All . | Selection . | |
| Eosinos | .0001 | <.0001 | .0001 | <.0001 |
| Age | <.0001 | <.0001 | <.0001 | <.0001 |
| Gender | .14 | .11 | .14 | .38 |
| Karnofsky | <.0001 | <.0001 | .18 | .34 |
| Stage4-151 | <.0001 | HD4 .27/HD5 .18/HD6 .34‡ | .19 | — |
| B symptoms | <.0001 | .0036 | .28 | — |
| Hist. subtype4-153 | .016 | .032 | .50 | — |
| Extranodal | <.0001 | .088 | .063 | .56 |
| LMM | .036 | .49 | .18 | — |
| ESR | <.0001 | .037 | .024 | .21 |
| HB | <.0001 | .14 | .57 | — |
| Albumin | <.0001 | .0002 | .10 | — |
| LDH | <.0002 | .024 | .026 | .10 |
| AP | <.0001 | .18 | .091 | — |
| Lymphocytes (blood) | .67 | .91 | .073 | — |
| Factor . | Univariate P-value . | Multivariate P-value . | ||
|---|---|---|---|---|
| Not Stratif. . | Stratified4-150 . | All . | Selection . | |
| Eosinos | .0001 | <.0001 | .0001 | <.0001 |
| Age | <.0001 | <.0001 | <.0001 | <.0001 |
| Gender | .14 | .11 | .14 | .38 |
| Karnofsky | <.0001 | <.0001 | .18 | .34 |
| Stage4-151 | <.0001 | HD4 .27/HD5 .18/HD6 .34‡ | .19 | — |
| B symptoms | <.0001 | .0036 | .28 | — |
| Hist. subtype4-153 | .016 | .032 | .50 | — |
| Extranodal | <.0001 | .088 | .063 | .56 |
| LMM | .036 | .49 | .18 | — |
| ESR | <.0001 | .037 | .024 | .21 |
| HB | <.0001 | .14 | .57 | — |
| Albumin | <.0001 | .0002 | .10 | — |
| LDH | <.0002 | .024 | .026 | .10 |
| AP | <.0001 | .18 | .091 | — |
| Lymphocytes (blood) | .67 | .91 | .073 | — |
Stratified according to treatment group, ie, early stage, intermediate stage and advanced stage.
Four categories: stage I to stage IV (Ann-Arbor classification).
Separate P-values for each strata: pooled value not available, since each stratum contains different stages.
(LP, LRCHD, and NS grade 1) versus (NS grade 2 and MC).
Further explanation and all abbreviations, see Table 3.