Table 4. Distributions of Mutations in... | American Society of Hematology

Table 4.

Distributions of Mutations in Tumor-Derived V_H Sequences

Patient	Region	Expected		Observed		P^4-150
Patient	Region	R	S	R	S	P^4-150
1	FR	42	15	29	23	<.01
	CDR	13	3	16	5	.07
2	FR	33	11	19	15	<.01
	CDR	9	2	15	6	.02
3	FR	35	13	16	16	<.01
	CDR	11	2	5	4	.12
4	FR	31	11	23	14	.02
	CDR	9	2	10	5	.14
5	FR	26	9	14	16	<.01
	CDR	8	2	10	5	.11

Patient	Region	Expected		Observed		P^4-150
Patient	Region	R	S	R	S	P^4-150
1	FR	42	15	29	23	<.01
	CDR	13	3	16	5	.07
2	FR	33	11	19	15	<.01
	CDR	9	2	15	6	.02
3	FR	35	13	16	16	<.01
	CDR	11	2	5	4	.12
4	FR	31	11	23	14	.02
	CDR	9	2	10	5	.14
5	FR	26	9	14	16	<.01
	CDR	8	2	10	5	.11

P is the probability of obtaining the number of R mutations by chance.