Activating RAS Point Mutations Among 20 Children With JMML
| Patient No. . | RAS Gene and Codon . | Alteration in DNA Sequence . | Effect on Protein . |
|---|---|---|---|
| 2 | NRAS 12 | GGT to GCT | Glycine to alanine |
| 5 | KRAS 13 | GGC to GAC | Glycine to aspartic acid |
| 13 | KRAS 12 | GGT to TGT | Glycine to cysteine |
| 16 | KRAS 12 | GGT to GTT | Glycine to valine |
| Patient No. . | RAS Gene and Codon . | Alteration in DNA Sequence . | Effect on Protein . |
|---|---|---|---|
| 2 | NRAS 12 | GGT to GCT | Glycine to alanine |
| 5 | KRAS 13 | GGC to GAC | Glycine to aspartic acid |
| 13 | KRAS 12 | GGT to TGT | Glycine to cysteine |
| 16 | KRAS 12 | GGT to GTT | Glycine to valine |