Table 2. TLS/FUS-ERG Transcript Types in... | American Society of Hematology

Table 2.

TLS/FUS-ERG Transcript Types in the t(16; 21)-AML Patients

Patient No.	Clinical Status	Sample Types	Collecting Time (mo)^*	Transcript Types
				A	B	C	D
1^†	AML	BM	6	+	+	+	−
	Relapse	BM^‡	18	+	+	+	−
	Relapse	PB	20.5	+	+	+	−
	Relapse	BM	22	+	+	+	−
2^†	MDS	BM	0	+	+	+	−
	AML	BM	5	+	+	+	−
	CR	BM	7	+	+	+	−
	CR	PB	8	−	±	−	−
	CR	PB	9	+	+	+	−
	CR	BM	12	+	+	±	−
	CR	BM	14	+	+	+	−
	Relapse	BM	15.5	+	+	+	−
3	Diagnosis	BM	0	+	+	+	−
	CR	BM	6	+	+	+	−
	Relapse	BM	16	+	+	+	−
4	Diagnosis	BM	0	+	+	+	−
	Relapse	BM	15	+	+	+	−
5	Diagnosis	BM	0	+	+	+	−
	CR	BM	3	+	+	+	−
	Relapse	BM	7	+	+	+	−
6	Diagnosis	BM	0	+	+	+	−
	CR	BM	3	+	+	+	−
	Relapse	BM	6	+	+	+	−
7	Diagnosis	BM	0	+	+	+	−
	CR	BM	3	+	+	+	−
	Relapse	BM	10	+	+	+	−
	Relapse	PB	12	+	+	+	−
8	Diagnosis	BM	0	+	+	+	−
	CR	PB	8	+	+	+	−
	Relapse	BM	11	+	+	+	−
9	Diagnosis	BM	0	+	+	+	−
	2nd relapse	BM	13	+	+	+	−
10	Diagnosis	BM	0	+	+	+	−
	CR	PB	6	−	−	−	−
	CR	BM	11	−	−	+	−
	CR	BM	15	+	+	+	−
11	Diagnosis	BM	0	−	−	−	+
	CR	BM	10	−	−	−	+
12	Diagnosis	BM	0	+	+	+	−
	CR	PB	3	+	+	±	−
13	Relapse	BM	14	+	+	+	−
14	Diagnosis	BM	0	+	+	+	−
15	Relapse	BM	10	+	+	+	−
16	Diagnosis	BM	0	+	+	+	−
17	Diagnosis	BM	0	+	+	+	−
18	Diagnosis	BM	0	+	+	+	−
19	Diagnosis	BM^‡	0	−	−	−	+

Patient No.	Clinical Status	Sample Types	Collecting Time (mo)^*	Transcript Types
				A	B	C	D
1^†	AML	BM	6	+	+	+	−
	Relapse	BM^‡	18	+	+	+	−
	Relapse	PB	20.5	+	+	+	−
	Relapse	BM	22	+	+	+	−
2^†	MDS	BM	0	+	+	+	−
	AML	BM	5	+	+	+	−
	CR	BM	7	+	+	+	−
	CR	PB	8	−	±	−	−
	CR	PB	9	+	+	+	−
	CR	BM	12	+	+	±	−
	CR	BM	14	+	+	+	−
	Relapse	BM	15.5	+	+	+	−
3	Diagnosis	BM	0	+	+	+	−
	CR	BM	6	+	+	+	−
	Relapse	BM	16	+	+	+	−
4	Diagnosis	BM	0	+	+	+	−
	Relapse	BM	15	+	+	+	−
5	Diagnosis	BM	0	+	+	+	−
	CR	BM	3	+	+	+	−
	Relapse	BM	7	+	+	+	−
6	Diagnosis	BM	0	+	+	+	−
	CR	BM	3	+	+	+	−
	Relapse	BM	6	+	+	+	−
7	Diagnosis	BM	0	+	+	+	−
	CR	BM	3	+	+	+	−
	Relapse	BM	10	+	+	+	−
	Relapse	PB	12	+	+	+	−
8	Diagnosis	BM	0	+	+	+	−
	CR	PB	8	+	+	+	−
	Relapse	BM	11	+	+	+	−
9	Diagnosis	BM	0	+	+	+	−
	2nd relapse	BM	13	+	+	+	−
10	Diagnosis	BM	0	+	+	+	−
	CR	PB	6	−	−	−	−
	CR	BM	11	−	−	+	−
	CR	BM	15	+	+	+	−
11	Diagnosis	BM	0	−	−	−	+
	CR	BM	10	−	−	−	+
12	Diagnosis	BM	0	+	+	+	−
	CR	PB	3	+	+	±	−
13	Relapse	BM	14	+	+	+	−
14	Diagnosis	BM	0	+	+	+	−
15	Relapse	BM	10	+	+	+	−
16	Diagnosis	BM	0	+	+	+	−
17	Diagnosis	BM	0	+	+	+	−
18	Diagnosis	BM	0	+	+	+	−
19	Diagnosis	BM^‡	0	−	−	−	+

Abbreviations: +, transcript was detectable; −, transcript was undetectable; ±, the band of the transcript was very faint.

Sample-collecting time (months) after diagnosis of MDS or AML.

†

The refractory anemia with excess of blasts in transformation (RAEBt) was precedent. Sample-collecting time (mo) in patients 1 and 2 means collecting time after diagnosis of MDS.

‡

The sample was used to evaluate the sensitivity of the RT-PCR in this study.

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