Risk and prognostic factors for chronic GVHD
| Factor . | Reference . | |
|---|---|---|
| Established risk factors | ||
| Previous acute GVHD, HLA disparities, recipient’s and donor’s age, peripheral blood stem cells, T-cell replete graft, controversial risk factors, male recipient/multiparous female donor, cord blood stem cells, viral infection, conditioning regimen | 62 | |
| Prognostic factors | 62 | |
| Thrombocytopenia, type of disease onset (progressive and overlap syndrome), extensive skin involvement, elevated bilirubin, lung involvement, gastrointestinal involvement (diarrhea), decreased performance status | ||
| Prognostic classifications | 18 | |
| Limited vs extensive | 79, 81 | |
| Johns Hopkins Hospital | 59 | |
| Center for International Blood and Marrow Transplant Research | 61, 63 | |
| NIH consensus classification | 4 |
| Factor . | Reference . | |
|---|---|---|
| Established risk factors | ||
| Previous acute GVHD, HLA disparities, recipient’s and donor’s age, peripheral blood stem cells, T-cell replete graft, controversial risk factors, male recipient/multiparous female donor, cord blood stem cells, viral infection, conditioning regimen | 62 | |
| Prognostic factors | 62 | |
| Thrombocytopenia, type of disease onset (progressive and overlap syndrome), extensive skin involvement, elevated bilirubin, lung involvement, gastrointestinal involvement (diarrhea), decreased performance status | ||
| Prognostic classifications | 18 | |
| Limited vs extensive | 79, 81 | |
| Johns Hopkins Hospital | 59 | |
| Center for International Blood and Marrow Transplant Research | 61, 63 | |
| NIH consensus classification | 4 |