Ten lessons from transplantation in CML
| No. . | Lesson . |
|---|---|
| 1 | Stem cells can circulate in the peripheral blood. |
| 2 | Peripheral blood and bone marrow stem cells will engraft after myeloablative therapy. |
| 3 | Autografting with Ph-positive cells can result in regeneration with Ph-negative cells. |
| 4 | Allografting can cure CML. |
| 5 | T-cell depletion is associated with an increased risk of relapse. |
| 6 | Infusion of lymphocytes can restore remission. |
| 7 | Elucidation of mechanisms of GVL effect |
| 8 | Development and clinical value of monitoring for minimal residual disease |
| 9 | EBMT (Gratwohl) score can be applied to all diseases. |
| 10 | Relapse can occur very late after transplantation and life-long vigilance is required. |
| No. . | Lesson . |
|---|---|
| 1 | Stem cells can circulate in the peripheral blood. |
| 2 | Peripheral blood and bone marrow stem cells will engraft after myeloablative therapy. |
| 3 | Autografting with Ph-positive cells can result in regeneration with Ph-negative cells. |
| 4 | Allografting can cure CML. |
| 5 | T-cell depletion is associated with an increased risk of relapse. |
| 6 | Infusion of lymphocytes can restore remission. |
| 7 | Elucidation of mechanisms of GVL effect |
| 8 | Development and clinical value of monitoring for minimal residual disease |
| 9 | EBMT (Gratwohl) score can be applied to all diseases. |
| 10 | Relapse can occur very late after transplantation and life-long vigilance is required. |