Hemorrhagic Events Among Recipients of HSCT
| . | No. of Events . | % . |
|---|---|---|
| Type of transplant | ||
| Allogeneic | 112 | 78 |
| Autologous | 31 | 22 |
| Platelet recovery | ||
| Pre | 126 | 89 |
| Post | 16 | 11 |
| Severity grade* | ||
| Moderate | 80 | 56 |
| Severe | 24 | 17 |
| Life-threatening | 39 | 27 |
| Cause of bleed | ||
| Invasive procedure | 17 | 12 |
| Coagulopathy | 6 | 4 |
| All other | 120 | 84 |
| Site of bleed | ||
| Genitourinary | 35 | 24 |
| Gastrointestinal | 31 | 22 |
| Oral/nasal/soft tissue | 24 | 16 |
| Diffuse alveolar hemorrhage | 21 | 15 |
| Other pulmonary | 10 | 7 |
| Intracranial | 10 | 7 |
| Vascular | 8 | 6 |
| Other | 4 | 3 |
| Platelet count on day of onset | ||
| Not available | 9 | 6 |
| <5,000/L | 5 | 3 |
| 6,000-10,000/L | 9 | 6 |
| 11,000-15,000/L | 17 | 12 |
| 16,000-20,000/L | 10 | 7 |
| 21,000-50,000/L | 58 | 41 |
| >50,000/L | 35 | 25 |
| . | No. of Events . | % . |
|---|---|---|
| Type of transplant | ||
| Allogeneic | 112 | 78 |
| Autologous | 31 | 22 |
| Platelet recovery | ||
| Pre | 126 | 89 |
| Post | 16 | 11 |
| Severity grade* | ||
| Moderate | 80 | 56 |
| Severe | 24 | 17 |
| Life-threatening | 39 | 27 |
| Cause of bleed | ||
| Invasive procedure | 17 | 12 |
| Coagulopathy | 6 | 4 |
| All other | 120 | 84 |
| Site of bleed | ||
| Genitourinary | 35 | 24 |
| Gastrointestinal | 31 | 22 |
| Oral/nasal/soft tissue | 24 | 16 |
| Diffuse alveolar hemorrhage | 21 | 15 |
| Other pulmonary | 10 | 7 |
| Intracranial | 10 | 7 |
| Vascular | 8 | 6 |
| Other | 4 | 3 |
| Platelet count on day of onset | ||
| Not available | 9 | 6 |
| <5,000/L | 5 | 3 |
| 6,000-10,000/L | 9 | 6 |
| 11,000-15,000/L | 17 | 12 |
| 16,000-20,000/L | 10 | 7 |
| 21,000-50,000/L | 58 | 41 |
| >50,000/L | 35 | 25 |
*Mild—greater than normally observed, estimated blood loss <250 mL; moderate—estimated loss between 250-500 mL, possibly needing blood replacement; severe—estimated loss >500 mL, requiring blood replacement; and life threatening—estimated loss >1,000 mL, or producing hypotension or intracranial bleed. Cases of pulmonary hemorrhage including diffuse alveolar hemorrhage were graded as life threatening.