Baseline demographics and characteristics
| Characteristic . | Patients, n (%) (N = 302)* . |
|---|---|
| Age, y | |
| Mean (SD) | 48.9 (15.6) |
| Median (min, max) | 50.0 (18, 86) |
| Female | 201 (67) |
| Race‡ | |
| White | 240 (79) |
| Asian† | 45 (15) |
| American Indian/Alaskan native | 13 (4) |
| African American | 4 (1) |
| Splenectomized | 115 (38) |
| Concomitant ITP medication use at baseline | 101 (33) |
| Baseline platelet counts, ×109 | |
| <30 | 211 (70) |
| 30-50 | 52 (17) |
| >50 | 39 (13) |
| Number of prior ITP therapies | |
| 1 | 67 (22) |
| 2 | 75 (25) |
| ≥3 | 160 (53) |
| Characteristic . | Patients, n (%) (N = 302)* . |
|---|---|
| Age, y | |
| Mean (SD) | 48.9 (15.6) |
| Median (min, max) | 50.0 (18, 86) |
| Female | 201 (67) |
| Race‡ | |
| White | 240 (79) |
| Asian† | 45 (15) |
| American Indian/Alaskan native | 13 (4) |
| African American | 4 (1) |
| Splenectomized | 115 (38) |
| Concomitant ITP medication use at baseline | 101 (33) |
| Baseline platelet counts, ×109 | |
| <30 | 211 (70) |
| 30-50 | 52 (17) |
| >50 | 39 (13) |
| Number of prior ITP therapies | |
| 1 | 67 (22) |
| 2 | 75 (25) |
| ≥3 | 160 (53) |
A total of 494 patients were enrolled in the previous studies feeding into EXTEND. Of these, 371 completed their first study and 302 were enrolled in EXTEND.
Asians included 4 patients of Central/South Asian heritage and 41 of Japanese, East Asian/Southeast Asian heritage.
Percentages do not add up to 100% because of rounding.