Demographic and clinical data of octogenarians with sickle cell disease
| . | Patient A . | Patient B . | Patient C . | Patient D . |
|---|---|---|---|---|
| Age/sex | 82/F | 86/F | 82/F | 82/F |
| Ancestry | African American | Italian American | African American | African Brazilian |
| Obstetrical history* | G3P1A2 | G2P1A1 | G5P5 | G2P2 |
| Diagnosis | SS | SS | Hb SC disease | Hb SC disease |
| VOCs/y | 1-2 | 0-1 | 0-3 | 0-1 |
| Cerebrovascular accident | No | No | No | No |
| Retinopathy | Yes | Yes | No | No |
| Cataracts | Yes | Yes, OU | No | Yes, OS |
| Deafness | No | No | No | Yes, left ear |
| ACS | No | No | No | Yes |
| Congestive heart failure | Yes | Yes | No | No |
| Hypertension | Yes | No | Yes | Yes |
| Avascular necrosis | Yes + right hip replacement | Yes + replacement of both hips and right knee | No | No |
| Leg ulcer | Yes | Yes | No | No |
| Splenomegaly | No | No | Yes | Yes |
| Cholecystectomy | Yes | No | Yes | No |
| Infection | Tuberculosis, pneumonia | Urinary tract infection | Clostridium difficile colitis | Tuberculosis |
| Transfusion | Frequent | Occasional | Occasional | Frequent |
| Iron overload | Yes | No | No | Yes |
| Comorbidity | Complete heart block, glaucoma OU, mild Parkinson disease | Paroxysmal AFIB, IBS, MVP, osteoporosis | Osteoma of mandible, depression | Diabetes mellitus type 2 |
| Smoking | No | No | No | No |
| Alcohol | No | Occasional | No | Occasional |
| Body mass index | 21.6 | 20.4 | 24.8 | 23.1 |
| Compliance | Excellent | Excellent | Excellent | Excellent |
| Family support | Excellent | Excellent | Excellent | Excellent |
| Status | Alive | Deceased | Deceased | Deceased |
| Cause of death | N/A | Cardiac complications | Unknown | ACS + septicemia |
| . | Patient A . | Patient B . | Patient C . | Patient D . |
|---|---|---|---|---|
| Age/sex | 82/F | 86/F | 82/F | 82/F |
| Ancestry | African American | Italian American | African American | African Brazilian |
| Obstetrical history* | G3P1A2 | G2P1A1 | G5P5 | G2P2 |
| Diagnosis | SS | SS | Hb SC disease | Hb SC disease |
| VOCs/y | 1-2 | 0-1 | 0-3 | 0-1 |
| Cerebrovascular accident | No | No | No | No |
| Retinopathy | Yes | Yes | No | No |
| Cataracts | Yes | Yes, OU | No | Yes, OS |
| Deafness | No | No | No | Yes, left ear |
| ACS | No | No | No | Yes |
| Congestive heart failure | Yes | Yes | No | No |
| Hypertension | Yes | No | Yes | Yes |
| Avascular necrosis | Yes + right hip replacement | Yes + replacement of both hips and right knee | No | No |
| Leg ulcer | Yes | Yes | No | No |
| Splenomegaly | No | No | Yes | Yes |
| Cholecystectomy | Yes | No | Yes | No |
| Infection | Tuberculosis, pneumonia | Urinary tract infection | Clostridium difficile colitis | Tuberculosis |
| Transfusion | Frequent | Occasional | Occasional | Frequent |
| Iron overload | Yes | No | No | Yes |
| Comorbidity | Complete heart block, glaucoma OU, mild Parkinson disease | Paroxysmal AFIB, IBS, MVP, osteoporosis | Osteoma of mandible, depression | Diabetes mellitus type 2 |
| Smoking | No | No | No | No |
| Alcohol | No | Occasional | No | Occasional |
| Body mass index | 21.6 | 20.4 | 24.8 | 23.1 |
| Compliance | Excellent | Excellent | Excellent | Excellent |
| Family support | Excellent | Excellent | Excellent | Excellent |
| Status | Alive | Deceased | Deceased | Deceased |
| Cause of death | N/A | Cardiac complications | Unknown | ACS + septicemia |
A, abortus; ACS, acute chest syndrome; AFIB, Atrial fibrillation; F, female; G, gravidity; Hb SC, sickle cell–hemoglobin C; IBS, irritable bowel syndrome; MVP, mitral valve prolapse; N/A, not applicable; OS, oculus sinister; OU, oculus uterque; P, parity; SS, sickle cell anemia; VOCs, vaso-occlusive crises.
Reported using the gravida/para/abortus system.