Table 2 Variables and prognostic score... | American Society of Hematology

Table 2

Variables and prognostic score values of the CMML genetic score

	CPSS cytogenetic risk group*	ASXL1	NRAS	RUNX1	SETBP1
Variable score
0	Low	Unmutated	Unmutated	Unmutated	Unmutated
1	Intermediate	Mutated	Mutated	—	Mutated
2	High	—	—	Mutated	—
Genetic risk group	Score
Low	0
Intermediate-1	1
Intermediate-2	2
High	≥3

	CPSS cytogenetic risk group*	ASXL1	NRAS	RUNX1	SETBP1
Variable score
0	Low	Unmutated	Unmutated	Unmutated	Unmutated
1	Intermediate	Mutated	Mutated	—	Mutated
2	High	—	—	Mutated	—
Genetic risk group	Score
Low	0
Intermediate-1	1
Intermediate-2	2
High	≥3

—

, Not applicable.

Cytogenetic risk groups are defined according to Such et al¹³: low, normal, and isolated –Y; intermediate, other abnormalities; and high, trisomy 8, complex karyotype (≥3 abnormalities), and abnormalities of chromosome 7.

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