Table 1 Discordant somatic CEBPA... | American Society of Hematology

Table 1

Discordant somatic CEBPA mutations at AML diagnosis and relapse

Patient	CEBPA somatic mutation-diagnosis		CEBPA somatic mutation-relapse		Time to relapse, years
Patient	Amino acid	Mutation	Amino acid	Mutation	Time to relapse, years
B.I.1	p.N281RfsX38	c.991_992insGA	p.K313del	c.1087_1089del	14
B.II.2	p.R306dup	c.1067_1068insGCG	p.L146PfsX24	c.586_587insC	1.3
E.I.1	p.R306_N307insALAPPR	c.1067_1068ins18bp	p.Q312dup	c.1084_1086dup	6.7
E.II.1	p.K313dup	c.1087_1089dup	Wild type	Wild type	6.6
F.IV.2	p.E309_Q311delinsLEAK	c.1075_1081delinsCTGGAGGCCA	p.N307_T318dup	c.1070_1105dup	19.9*
G.II.2	p.K313dup	c.1087_1089dup	p.K313dup	c.1087_1089dup	2.3

Patient	CEBPA somatic mutation-diagnosis		CEBPA somatic mutation-relapse		Time to relapse, years
Patient	Amino acid	Mutation	Amino acid	Mutation	Time to relapse, years
B.I.1	p.N281RfsX38	c.991_992insGA	p.K313del	c.1087_1089del	14
B.II.2	p.R306dup	c.1067_1068insGCG	p.L146PfsX24	c.586_587insC	1.3
E.I.1	p.R306_N307insALAPPR	c.1067_1068ins18bp	p.Q312dup	c.1084_1086dup	6.7
E.II.1	p.K313dup	c.1087_1089dup	Wild type	Wild type	6.6
F.IV.2	p.E309_Q311delinsLEAK	c.1075_1081delinsCTGGAGGCCA	p.N307_T318dup	c.1070_1105dup	19.9*
G.II.2	p.K313dup	c.1087_1089dup	p.K313dup	c.1087_1089dup	2.3

Third relapse.