Table 1 Combination index of MLN4924... | American Society of Hematology

Table 1

Combination index of MLN4924 with bortezomib

Cell line	MLN4924 dose, µM	Bortezomib dose, nM	CI
OPM2	5	4	0.17836
	5	8	0.14499
	10	4	0.10951
	10	8	0.11097
U266	2.5	4	0.42012
	5	4	0.40122
	10	4	0.39735
	20	4	0.40017
MM.1S	1.25	4	0.47348
	2.5	4	0.43892
	1.25	8	0.42433
	2.5	8	0.43257
RPMI8226	0.625	4	0.47984
	1.25	4	0.68028
	2.5	4	0.71090
	2.5	2	0.96746
MM.1R	0.625	2	0.78764
	1.25	2	0.86669
	2.5	2	0.59118
	2.5	4	0.65250

Cell line	MLN4924 dose, µM	Bortezomib dose, nM	CI
OPM2	5	4	0.17836
	5	8	0.14499
	10	4	0.10951
	10	8	0.11097
U266	2.5	4	0.42012
	5	4	0.40122
	10	4	0.39735
	20	4	0.40017
MM.1S	1.25	4	0.47348
	2.5	4	0.43892
	1.25	8	0.42433
	2.5	8	0.43257
RPMI8226	0.625	4	0.47984
	1.25	4	0.68028
	2.5	4	0.71090
	2.5	2	0.96746
MM.1R	0.625	2	0.78764
	1.25	2	0.86669
	2.5	2	0.59118
	2.5	4	0.65250

CI, combination index.