Toxicities
| Patient . | Toxicities*† . |
|---|---|
| 1‡ | Fatigue, herpes zoster with secondary otitis externa 6 months after treatment |
| 2 | Escherichia coli bacteremia, died with influenza pneumonia, dyspnea, hypoxemia, nonbacterial thrombotic endocarditis, cerebral infarction, elevated liver enzymes |
| 3 | Hypotension, acute renal failure, hypoxemia, hyperbilirubinemia, capillary leak syndrome |
| 4 | Diarrhea, fatigue |
| 5 | Fever, fatigue, hypotension |
| 6 | Hypotension, capillary leak syndrome, hypoalbuminemia |
| 7 | Obtundation, acute renal failure, hyperbilirubinemia, capillary leak syndrome, anorexia, elevated liver enzymes, electrolyte abnormalities |
| 8 | Hypotension, obtundation, acute renal failure, capillary leak syndrome, headache, pleural effusion, electrolyte abnormalities |
| Patient . | Toxicities*† . |
|---|---|
| 1‡ | Fatigue, herpes zoster with secondary otitis externa 6 months after treatment |
| 2 | Escherichia coli bacteremia, died with influenza pneumonia, dyspnea, hypoxemia, nonbacterial thrombotic endocarditis, cerebral infarction, elevated liver enzymes |
| 3 | Hypotension, acute renal failure, hypoxemia, hyperbilirubinemia, capillary leak syndrome |
| 4 | Diarrhea, fatigue |
| 5 | Fever, fatigue, hypotension |
| 6 | Hypotension, capillary leak syndrome, hypoalbuminemia |
| 7 | Obtundation, acute renal failure, hyperbilirubinemia, capillary leak syndrome, anorexia, elevated liver enzymes, electrolyte abnormalities |
| 8 | Hypotension, obtundation, acute renal failure, capillary leak syndrome, headache, pleural effusion, electrolyte abnormalities |
All grade 3 and 4 toxicities by the Cancer Therapy Evaluation Program Common Terminology Criteria for Adverse Events Version 3, are listed.
All patients had pancytopenia with chemotherapy.
Patient 1 was treated twice. Only his second treatment is reported here. The first treatment has been previously reported (21).