Patient characteristics (n = 167)
| Demographics | |
| Age, y | 60 ± 17 |
| Sex, male/female, n | 96/74 |
| Weight, kg | 84 ± 19 |
| Height, cm | 171 ± 10 |
| Ethnicity | |
| White | 159 (95.2) |
| Black | 4 (2.4) |
| Asian | 3 (1.8) |
| Other | 1 (0.6) |
| Prescribed medication | |
| Amiodarone | 2 (1.2) |
| Statins | 45 (26.9) |
| Antiplatelet drugs | 55 (32.9) |
| Antibiotics | 6 (3.6) |
| Antifungal drugs | 1 (0.6) |
| NSAIDs | 12 (7.2) |
| Indication for warfarin | |
| Atrial fibrillation | 61 (36.6) |
| Deep vein thrombosis | 77 (46.1) |
| Pulmonary embolism | 21 (12.6) |
| Other | 8 (4.7) |
| Prescribed warfarin dose | |
| Mean maintenance dose, mg/d | 5.54 |
| CYP2C9 | |
| *1/*1 | 119 (71.3) |
| *1/*2 | 29 (17.4) |
| *1/*3 | 14 (8.4) |
| *2/*2 | 3 (1.7) |
| *2/*3 | 2 (1.2) |
| *3/*3 | 0 |
| VKORC1 −1639 | |
| G/G | 66 (39.5) |
| G/A | 75 (44.9) |
| A/A | 26 (15.6) |
| CYP4F2 c.1297 | |
| C/C | 80 (48.6) |
| C/T | 68 (40.7) |
| T/T | 19 (11.3) |
| Demographics | |
| Age, y | 60 ± 17 |
| Sex, male/female, n | 96/74 |
| Weight, kg | 84 ± 19 |
| Height, cm | 171 ± 10 |
| Ethnicity | |
| White | 159 (95.2) |
| Black | 4 (2.4) |
| Asian | 3 (1.8) |
| Other | 1 (0.6) |
| Prescribed medication | |
| Amiodarone | 2 (1.2) |
| Statins | 45 (26.9) |
| Antiplatelet drugs | 55 (32.9) |
| Antibiotics | 6 (3.6) |
| Antifungal drugs | 1 (0.6) |
| NSAIDs | 12 (7.2) |
| Indication for warfarin | |
| Atrial fibrillation | 61 (36.6) |
| Deep vein thrombosis | 77 (46.1) |
| Pulmonary embolism | 21 (12.6) |
| Other | 8 (4.7) |
| Prescribed warfarin dose | |
| Mean maintenance dose, mg/d | 5.54 |
| CYP2C9 | |
| *1/*1 | 119 (71.3) |
| *1/*2 | 29 (17.4) |
| *1/*3 | 14 (8.4) |
| *2/*2 | 3 (1.7) |
| *2/*3 | 2 (1.2) |
| *3/*3 | 0 |
| VKORC1 −1639 | |
| G/G | 66 (39.5) |
| G/A | 75 (44.9) |
| A/A | 26 (15.6) |
| CYP4F2 c.1297 | |
| C/C | 80 (48.6) |
| C/T | 68 (40.7) |
| T/T | 19 (11.3) |
Values are mean ± SD or n (%), unless otherwise indicated.
NSAIDs indicates nonsteroidal anti-inflammatory drugs.