Table 2 Interaction of leukocyte and... | American Society of Hematology

Table 2

Interaction of leukocyte and platelet counts at diagnosis (multivariable model)¹¹

Interaction, value ×10⁹/L	n (%)*	Rate of vascular event†	Low risk‡ (%)	JAK2V617F§ (%)	RR (P)	(95% CI)
(1) WBC < 11 + PLT > 1000	170 (16)	1.59	95 (56)	35 (26)	1	—
(2) WBC < 11 + PLT < 1000	644 (62)	2.26	317 (49)	304 (56)	1.92 (.034)	(1.07-2.87)
(3) WBC > 11 + PLT > 1000	99 (9)	2.88	41 (41)	40 (61)	2.38 (.026)	(1.11-3.51)
(4) WBC > 11 + PLT < 1000	130 (12)	2.95	52 (40)	75 (77)	2.43 (.017)	(1.25-2.94)

Interaction, value ×10⁹/L	n (%)*	Rate of vascular event†	Low risk‡ (%)	JAK2V617F§ (%)	RR (P)	(95% CI)
(1) WBC < 11 + PLT > 1000	170 (16)	1.59	95 (56)	35 (26)	1	—
(2) WBC < 11 + PLT < 1000	644 (62)	2.26	317 (49)	304 (56)	1.92 (.034)	(1.07-2.87)
(3) WBC > 11 + PLT > 1000	99 (9)	2.88	41 (41)	40 (61)	2.38 (.026)	(1.11-3.51)
(4) WBC > 11 + PLT < 1000	130 (12)	2.95	52 (40)	75 (77)	2.43 (.017)	(1.25-2.94)

Twenty patients were excluded because of WBC or platelet count data missing at diagnosis.

Percentage of patients per year.

Age younger than 60 years and no previous thrombosis; untreated (90%).

Percentage calculated on 860 patients with JAK2V617F status evaluated.