Results of univariate analyses of gene expression with overall survival
| Gene . | CHOP . | CHOP plus R . | ||||
|---|---|---|---|---|---|---|
| HR . | P . | 2-yr OS*, % . | HR . | P . | 2-yr OS*, % . | |
| BCL6 | 0.65 | .008† | 69, 52 | 0.62 | .007† | 82, 69 |
| GCET1 (SERPINA9) | 0.75 | .01† | 69, 53 | 0.62 | .013† | 83, 68 |
| GCET2 | 0.93 | .608 | 59, 66 | 0.93 | .608 | 77, 74 |
| HLA-DPA1 | 0.71 | .036† | 63, 58 | 0.77 | .115 | 84, 68 |
| HLA-DQA1 | 1.14 | .35 | 63, 62 | 0.65 | .020 | 83, 68 |
| HLA-DRA | 0.72 | .02† | 63, 58 | 0.91 | .580 | 84, 68 |
| HLA-DRB | 0.98 | .921 | 58, 66 | 0.71 | .030† | 89, 62 |
| ACTN1 | 0.66 | .03† | 73, 49 | 0.62 | .011† | 85, 66 |
| COL3A1 | 0.78 | .016† | 71, 50 | 0.67 | .029† | 81, 69 |
| CTGF | 0.79 | .026† | 75, 45 | 0.80 | .211 | 84, 67 |
| FN1 | 0.77 | .01† | 67, 54 | 0.73 | .078 | 78, 73 |
| FAM38A | 1.16 | .462 | 61, 60 | 0.85 | .426 | 80, 71 |
| PLAU | 0.73 | .122 | 68, 54 | 0.56 | .001† | 84, 67 |
| MYC | 1.40 | .047† | 54, 67 | 1.64 | .007† | 65, 86 |
| C20ORF155 | 1.32 | .369 | 52, 70 | 1.03 | .851 | 72, 79 |
| NPM3 | 1.27 | .25 | 58, 64 | 1.22 | .303 | 74, 76 |
| BMP6 | 1.26 | .216 | 64, 60 | 0.86 | .402 | 77, 74 |
| LMO2 | 1.03 | .832 | 57, 64 | 0.62 | .011† | 82, 69 |
| BCL2 | 1.44 | .018† | 57, 66 | 1.11 | .569 | 71, 80 |
| CCL3 | 1.40 | .062 | 48, 73 | 0.82 | .296 | 84, 67 |
| CCND2 | 1.45 | .002† | 53, 69 | 1.23 | .271 | 76, 75 |
| DRP2 | 1.02 | .878 | 66, 60 | 0.94 | .719 | 75, 76 |
| PRKCB1 | 1.47 | .028† | 51, 71 | 0.99 | .951 | 79, 73 |
| PDCD4 | 1.89 | .001† | 50, 73 | 1.53 | .023† | 67, 84 |
| MAP1B | 1.05 | .772 | 63, 64 | 0.94 | .717 | 78, 72 |
| TLE1 | 1.60 | .001† | 42, 80 | 1.16 | .428 | 70, 81 |
| SLC25A13 | 1.15 | .676 | 58, 63 | 0.89 | .540 | 78, 73 |
| PDE4B | 1.19 | .423 | 56, 64 | 1.17 | .402 | 75, 76 |
| B4GALT1 | 1.87 | .001† | 49, 71 | 0.82 | .258 | 80, 72 |
| PRKCG | 1.05 | .701 | 49, 72 | 1.02 | .924 | 77, 71 |
| OVGP1 | 1.25 | .279 | 52, 73 | 1.02 | .924 | 77, 71 |
| NR4A3 | 1.30 | .151 | 49, 71 | 0.80 | .227 | 72, 80 |
| ZNF212 | 0.99 | .965 | 58, 64 | 1.04 | .810 | 73, 78 |
| HTR2B | 1.04 | .834 | 48, 68 | 0.76 | .210 | 81, 64 |
| CAT | 1.24 | .50 | 54, 67 | 0.99 | .962 | 80, 71 |
| SOD2 | 1.10 | .573 | 60, 61 | 0.64 | .014† | 87, 64 |
| Gene . | CHOP . | CHOP plus R . | ||||
|---|---|---|---|---|---|---|
| HR . | P . | 2-yr OS*, % . | HR . | P . | 2-yr OS*, % . | |
| BCL6 | 0.65 | .008† | 69, 52 | 0.62 | .007† | 82, 69 |
| GCET1 (SERPINA9) | 0.75 | .01† | 69, 53 | 0.62 | .013† | 83, 68 |
| GCET2 | 0.93 | .608 | 59, 66 | 0.93 | .608 | 77, 74 |
| HLA-DPA1 | 0.71 | .036† | 63, 58 | 0.77 | .115 | 84, 68 |
| HLA-DQA1 | 1.14 | .35 | 63, 62 | 0.65 | .020 | 83, 68 |
| HLA-DRA | 0.72 | .02† | 63, 58 | 0.91 | .580 | 84, 68 |
| HLA-DRB | 0.98 | .921 | 58, 66 | 0.71 | .030† | 89, 62 |
| ACTN1 | 0.66 | .03† | 73, 49 | 0.62 | .011† | 85, 66 |
| COL3A1 | 0.78 | .016† | 71, 50 | 0.67 | .029† | 81, 69 |
| CTGF | 0.79 | .026† | 75, 45 | 0.80 | .211 | 84, 67 |
| FN1 | 0.77 | .01† | 67, 54 | 0.73 | .078 | 78, 73 |
| FAM38A | 1.16 | .462 | 61, 60 | 0.85 | .426 | 80, 71 |
| PLAU | 0.73 | .122 | 68, 54 | 0.56 | .001† | 84, 67 |
| MYC | 1.40 | .047† | 54, 67 | 1.64 | .007† | 65, 86 |
| C20ORF155 | 1.32 | .369 | 52, 70 | 1.03 | .851 | 72, 79 |
| NPM3 | 1.27 | .25 | 58, 64 | 1.22 | .303 | 74, 76 |
| BMP6 | 1.26 | .216 | 64, 60 | 0.86 | .402 | 77, 74 |
| LMO2 | 1.03 | .832 | 57, 64 | 0.62 | .011† | 82, 69 |
| BCL2 | 1.44 | .018† | 57, 66 | 1.11 | .569 | 71, 80 |
| CCL3 | 1.40 | .062 | 48, 73 | 0.82 | .296 | 84, 67 |
| CCND2 | 1.45 | .002† | 53, 69 | 1.23 | .271 | 76, 75 |
| DRP2 | 1.02 | .878 | 66, 60 | 0.94 | .719 | 75, 76 |
| PRKCB1 | 1.47 | .028† | 51, 71 | 0.99 | .951 | 79, 73 |
| PDCD4 | 1.89 | .001† | 50, 73 | 1.53 | .023† | 67, 84 |
| MAP1B | 1.05 | .772 | 63, 64 | 0.94 | .717 | 78, 72 |
| TLE1 | 1.60 | .001† | 42, 80 | 1.16 | .428 | 70, 81 |
| SLC25A13 | 1.15 | .676 | 58, 63 | 0.89 | .540 | 78, 73 |
| PDE4B | 1.19 | .423 | 56, 64 | 1.17 | .402 | 75, 76 |
| B4GALT1 | 1.87 | .001† | 49, 71 | 0.82 | .258 | 80, 72 |
| PRKCG | 1.05 | .701 | 49, 72 | 1.02 | .924 | 77, 71 |
| OVGP1 | 1.25 | .279 | 52, 73 | 1.02 | .924 | 77, 71 |
| NR4A3 | 1.30 | .151 | 49, 71 | 0.80 | .227 | 72, 80 |
| ZNF212 | 0.99 | .965 | 58, 64 | 1.04 | .810 | 73, 78 |
| HTR2B | 1.04 | .834 | 48, 68 | 0.76 | .210 | 81, 64 |
| CAT | 1.24 | .50 | 54, 67 | 0.99 | .962 | 80, 71 |
| SOD2 | 1.10 | .573 | 60, 61 | 0.64 | .014† | 87, 64 |