Table 4 Multivariate analysis of... | American Society of Hematology

Table 4

Multivariate analysis of survival among patients 16 years of age and older who underwent URD transplants for Philadelphia-negative ALL in CR1

Variable	Event/no. evaluable	Relative risk of death (95% CI)	P
WBC at diagnosis
100 × 10⁹/L or less*	72/113	1.00§
More than 100 × 10⁹/L	25/38	1.73 (1.08-2.77)	P₁₂ = .023
Unknown	11/14	2.32 (1.21-4.48)	P₁₃ = .012
Time from diagnosis to CR1
8 wk or less†	52/97	1.00§
More than 8 wk	45/68	1.74 (1.16-2.62)	.008
Donor-recipient CMV status
D⁻/R⁻	28/54	1.00§
D⁺ or R⁺	69/111	1.62 (1.02-2.56)	.040
Donor-recipient HLA match
Well or partially matched‡	75/136	1.00§
Mismatched	22/29	1.88 (1.16-3.05)	.010
T-cell depletion
No	84/149	1.00§
Yes	13/16	2.62 (1.43-4.80)	.002

Variable	Event/no. evaluable	Relative risk of death (95% CI)	P
WBC at diagnosis
100 × 10⁹/L or less*	72/113	1.00§
More than 100 × 10⁹/L	25/38	1.73 (1.08-2.77)	P₁₂ = .023
Unknown	11/14	2.32 (1.21-4.48)	P₁₃ = .012
Time from diagnosis to CR1
8 wk or less†	52/97	1.00§
More than 8 wk	45/68	1.74 (1.16-2.62)	.008
Donor-recipient CMV status
D⁻/R⁻	28/54	1.00§
D⁺ or R⁺	69/111	1.62 (1.02-2.56)	.040
Donor-recipient HLA match
Well or partially matched‡	75/136	1.00§
Mismatched	22/29	1.88 (1.16-3.05)	.010
T-cell depletion
No	84/149	1.00§
Yes	13/16	2.62 (1.43-4.80)	.002

Thirty to 100 × 10⁹/L versus less than 30 × 10⁹/L: RR = 0.97 (0.56-1.68); P = .91.

Less than four weeks versus 4 to 8 weeks: RR = 0.73 (0.41-1.30); P = .28.

Partially matched versus well matched: RR = 1.03 (0.64-1.65); P = .90.

Reference group.