Table 1 Cytogenetic distribution of... | American Society of Hematology

Table 1

Cytogenetic distribution of patients with adult acute lymphoblastic leukemia on MRC UKALLXII/ECOG 2993

Cytogenetic subgroup*	t(9;22)	t(4;11)	t(11q23)	t(1;19)	t(8;14)	t(10;14)	TCR	t(14q32)	del(6q)	del(7p)	−7	+8	+X	del(9p)	abn(11q)	del(12p)	del(13q)	del(17p)	Complex	Ho-Tr	HeH	Tt
t(9;22)(q24;q11.2)†	209
t(4;11)(q21;q23)	0	54
Other MLL/11q23 translocations	0	0	15
t(1;19)(q21;p13.3)	0	0	0	24
t(8;14)(q24.1;q32)	0	0	0	0	16
t(10;14)(q24;q11.2)	0	0	0	0	0	16
Other TCR translocations	0	0	0	0	0	0	18
14q32 translocations	4	0	0	0	3	0	2	49
del(6q)	6	0	1	4	0	0	3	8	61
del(7p)	7	3	1	2	0	0	0	2	0	30
−7‡	31	0	0	0	0	0	0	1	2	2	62
+8‡	24	1	1	2	0	1	1	5	5	3	6	85
+X‡	23	10	1	0	2	0	0	8	8	3	3	35	129
del(9p)	24	0	0	4	0	5	1	5	4	11	7	7	0	95
Abnormality of 11q	7	0	1	0	1	0	1	3	4	1	3	1	4	4	36
del(12p)	1	1	0	0	0	0	1	3	4	2	1	0	1	1	1	30
del(13q)/−13	5	0	2	2	2	0	1	5	4	1	10	4	6	7	2	3	45
del(17p)	3	1	0	0	2	0	0	3	4	0	10	9	11	3	3	2	16	43
Complex karyotype	NA	NA	NA	NA	NA	NA	NA	NA	10	1	5	3	4	8	7	7	5	6	41
Low hypodiploidy/near triploidy	0	0	0	0	0	0	0	1	1	0	9	18	16	3	0	0	12	12	0	31
High hyperdiploidy	29	1	1	0	2	0	0	6	5	2	3	31	77	0	1	1	3	7	0	0	106
Tetraploidy	2	0	0	0	0	0	0	0	2	1	2	2	0	1	3	2	2	3	0	0	0	17

Cytogenetic subgroup*	t(9;22)	t(4;11)	t(11q23)	t(1;19)	t(8;14)	t(10;14)	TCR	t(14q32)	del(6q)	del(7p)	−7	+8	+X	del(9p)	abn(11q)	del(12p)	del(13q)	del(17p)	Complex	Ho-Tr	HeH	Tt
t(9;22)(q24;q11.2)†	209
t(4;11)(q21;q23)	0	54
Other MLL/11q23 translocations	0	0	15
t(1;19)(q21;p13.3)	0	0	0	24
t(8;14)(q24.1;q32)	0	0	0	0	16
t(10;14)(q24;q11.2)	0	0	0	0	0	16
Other TCR translocations	0	0	0	0	0	0	18
14q32 translocations	4	0	0	0	3	0	2	49
del(6q)	6	0	1	4	0	0	3	8	61
del(7p)	7	3	1	2	0	0	0	2	0	30
−7‡	31	0	0	0	0	0	0	1	2	2	62
+8‡	24	1	1	2	0	1	1	5	5	3	6	85
+X‡	23	10	1	0	2	0	0	8	8	3	3	35	129
del(9p)	24	0	0	4	0	5	1	5	4	11	7	7	0	95
Abnormality of 11q	7	0	1	0	1	0	1	3	4	1	3	1	4	4	36
del(12p)	1	1	0	0	0	0	1	3	4	2	1	0	1	1	1	30
del(13q)/−13	5	0	2	2	2	0	1	5	4	1	10	4	6	7	2	3	45
del(17p)	3	1	0	0	2	0	0	3	4	0	10	9	11	3	3	2	16	43
Complex karyotype	NA	NA	NA	NA	NA	NA	NA	NA	10	1	5	3	4	8	7	7	5	6	41
Low hypodiploidy/near triploidy	0	0	0	0	0	0	0	1	1	0	9	18	16	3	0	0	12	12	0	31
High hyperdiploidy	29	1	1	0	2	0	0	6	5	2	3	31	77	0	1	1	3	7	0	0	106
Tetraploidy	2	0	0	0	0	0	0	0	2	1	2	2	0	1	3	2	2	3	0	0	0	17

NA indicates not applicable.

See “Patients, materials, and methods” for a full definition of the individual cytogenetic subgroups.

Only cases with a cytogenetically visible t(9;22)(q34;q11.2) are included.

Gain or loss of whole chromosomes from diploid or tetraploid.