Human mHAs
| Mechanism underlying immunogenicity and name . | Gene/chromosome . | Tissue distribution . |
|---|---|---|
| Nonsynonymous coding SNP(s) | ||
| HA-1 | KIAA0223/19p13.3 | Hematopoietic |
| HA-2 | MYO1G/7p12p13 | Hematopoietic |
| HA-3 | LBC/15q24q25 | Ubiquitous |
| HA-8 | KIAA0020/9p24.2 | Ubiquitous |
| HB-1 | 5q32 | B-lymphoid cells |
| BCL2A1 | BCL2A1/15q24.3 | Hematopoietic |
| Polymorphism with chromosome X | ||
| SMCY | Yq11.1 | Ubiquitous |
| DFFRY | Yq11 | Ubiquitous |
| UTY | Yq11.1 | Ubiquitous |
| DBY | Yq11 | Ubiquitous |
| RPS4Y | Yp11.3 | Ubiquitous |
| Homozygous gene deletion | ||
| UGT2B17 | UGT2B17/4q13 | Ubiquitous |
| Deletion SNP causing a frameshift | ||
| LRH-1 | P2X5/17p13.2 | Hematopoietic |
| NS cSNP causing a stop codon | ||
| PANE1 | PANE1/22q13 | B-lymphoid cells |
| NS cSNP in an alternatively translated peptide | ||
| ECGF-1 | ECGF-1/22q13 | Hematopoietic |
| NS cSNP resulting in alternate splicing | ||
| SP110 | SP11O/2q37 | Hematopoietic |
| Unconventional ORF | ||
| TMSB4Y | Yq11 | Ubiquitous |
| Mechanism underlying immunogenicity and name . | Gene/chromosome . | Tissue distribution . |
|---|---|---|
| Nonsynonymous coding SNP(s) | ||
| HA-1 | KIAA0223/19p13.3 | Hematopoietic |
| HA-2 | MYO1G/7p12p13 | Hematopoietic |
| HA-3 | LBC/15q24q25 | Ubiquitous |
| HA-8 | KIAA0020/9p24.2 | Ubiquitous |
| HB-1 | 5q32 | B-lymphoid cells |
| BCL2A1 | BCL2A1/15q24.3 | Hematopoietic |
| Polymorphism with chromosome X | ||
| SMCY | Yq11.1 | Ubiquitous |
| DFFRY | Yq11 | Ubiquitous |
| UTY | Yq11.1 | Ubiquitous |
| DBY | Yq11 | Ubiquitous |
| RPS4Y | Yp11.3 | Ubiquitous |
| Homozygous gene deletion | ||
| UGT2B17 | UGT2B17/4q13 | Ubiquitous |
| Deletion SNP causing a frameshift | ||
| LRH-1 | P2X5/17p13.2 | Hematopoietic |
| NS cSNP causing a stop codon | ||
| PANE1 | PANE1/22q13 | B-lymphoid cells |
| NS cSNP in an alternatively translated peptide | ||
| ECGF-1 | ECGF-1/22q13 | Hematopoietic |
| NS cSNP resulting in alternate splicing | ||
| SP110 | SP11O/2q37 | Hematopoietic |
| Unconventional ORF | ||
| TMSB4Y | Yq11 | Ubiquitous |
NS indicates nonsynonymous; cSNP, coding single nucleotide polymorphism; ORF, open reading frame.