Table 1. Clinical features and... | American Society of Hematology

Table 1.

Clinical features and laboratory characteristics of 60 pediatric patients with AML recruited from the AML-BFM studies 1998 and 2004

Characteristic	No exon 11 cITD	kit cITD
Median age, y (range)^*	10 (0.5-18.8)	13.7 (9.7-16.6)
Male/female, %^*	55/45	75/25
Median WBC count, × 10⁹/L (range)^*	66.5 (1.8-550)	21.4 (4-48)
Marrow blast, % (range)^*	81 (0-98)	67 (45-89)
FAB class, no. (%)^*
M0	4 (6)	0 (0)
M1	7 (12)	0 (0)
M2	21 (39)	2 (50)
M3	2 (4)	0 (0)
M4	8 (14)	0 (0)
M5	13 (23)	2 (50)
M6	0 (0)	0 (0)
M7	1 (2)	0 (0)
Karyotype, no. (%)†
Normal	11 (22)	0 (0)
t(15;17)	2 (4)	0 (0)
t(8;21)	10 (20)	2 (67)
t(9;11)	5 (10)	1 (33)
t(4;11)	6 (12)	0 (0)
Inv 16	2 (4)	0 (0)
Trisomy 8	2 (4)	0 (0)
-9	2 (4)	0 (0)
Other	10 (20)	0 (0)

Characteristic	No exon 11 cITD	kit cITD
Median age, y (range)^*	10 (0.5-18.8)	13.7 (9.7-16.6)
Male/female, %^*	55/45	75/25
Median WBC count, × 10⁹/L (range)^*	66.5 (1.8-550)	21.4 (4-48)
Marrow blast, % (range)^*	81 (0-98)	67 (45-89)
FAB class, no. (%)^*
M0	4 (6)	0 (0)
M1	7 (12)	0 (0)
M2	21 (39)	2 (50)
M3	2 (4)	0 (0)
M4	8 (14)	0 (0)
M5	13 (23)	2 (50)
M6	0 (0)	0 (0)
M7	1 (2)	0 (0)
Karyotype, no. (%)†
Normal	11 (22)	0 (0)
t(15;17)	2 (4)	0 (0)
t(8;21)	10 (20)	2 (67)
t(9;11)	5 (10)	1 (33)
t(4;11)	6 (12)	0 (0)
Inv 16	2 (4)	0 (0)
Trisomy 8	2 (4)	0 (0)
-9	2 (4)	0 (0)
Other	10 (20)	0 (0)

WBC indicates white blood cell

For the “No exon 11 cITD” column, n = 56; for the “kit cITD” column, n = 4

For the “No exon 11 cITD” column, n = 50; for the “kit cITD” column, n = 3