Table 4. TCR Vβ use by T-cell clones... | American Society of Hematology

Table 4.

TCR Vβ use by T-cell clones found in the 13 patients studied and by Sézary cell lines

	T-cell clones defined by immunoscopy			Expanded T-cell clones phenotypically characterized
TCR Vβ family	PBMC, 13 patients	Skin, 3 patients	Malignant + SCLs	Nonmalignant	Total
1	0	0	0	0	0
2	1	1	1	0	1
3	3	0	0	0	0
4	1	0	0	0	0
5	2	0	0	0	0
6	1	0	0	0	0
7	1	0	1	0	1
8	2	1	2	0	2
9	0	0	0	0	0
11	1	0	1	0	1
12	0	0	0	0	0
13	1	0	1	0	1
14	2	0	0	2	2
15	2	1	0	0	0
16	1	1	0	0	0
17	4	1	1	1	2
18	1	0	0	0	0
20	1	0	0	0	0
21	1	0	0	0	0
22	2	0	1	2	3
23	2	0	1	0	1
24	0	0	0	0	0
Total	28	5	9	5	14

	T-cell clones defined by immunoscopy			Expanded T-cell clones phenotypically characterized
TCR Vβ family	PBMC, 13 patients	Skin, 3 patients	Malignant + SCLs	Nonmalignant	Total
1	0	0	0	0	0
2	1	1	1	0	1
3	3	0	0	0	0
4	1	0	0	0	0
5	2	0	0	0	0
6	1	0	0	0	0
7	1	0	1	0	1
8	2	1	2	0	2
9	0	0	0	0	0
11	1	0	1	0	1
12	0	0	0	0	0
13	1	0	1	0	1
14	2	0	0	2	2
15	2	1	0	0	0
16	1	1	0	0	0
17	4	1	1	1	2
18	1	0	0	0	0
20	1	0	0	0	0
21	1	0	0	0	0
22	2	0	1	2	3
23	2	0	1	0	1
24	0	0	0	0	0
Total	28	5	9	5	14

Phenotypic characterization of expanded T-cell clones relies on TCR Vβ, CD 158k, and cell-surface VIM expression. For PBMCs, n = 13 patients; for skin, n = 3.

SCLs indicates Sézary cell lines (HUT78 and Pno).

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