Scores of FVIII AR to DDAVP
| AR . | |||||||
|---|---|---|---|---|---|---|---|
| . | Total . | Absent . | Partial . | Complete . | P value . | Complete ≥0.8 . | P value . |
| F8 variants, n (%) | |||||||
| Null | 143 | 1 (0.7) | 11 (7.7) | 130 (90.9) | .0059 | 102 (71.3) | .0092 |
| Non-null | 218 | 0 (0) | 4 (1.8) | 214 (98.2) | 181 (83.0) | ||
| Severity of the familial HA, n (%) | |||||||
| Severe/moderate | 216 | 1 (0.5) | 13 (6.0) | 202 (93.5) | .0416 | 160 (74.1) | .0091 |
| 124 (85.5) | |||||||
| Mild | 145 | 0 (0) | 2 (1.4) | 143 (98.6) | |||
| Basal VWF levels (IU/mL), n (%) | |||||||
| <0.7 | 127 | 0 (0) | 4 (3.1) | 123 (96.9) | .8592 | 103 (81.1) | .2804 |
| ≥0.7 | 207 | 1 (0.5) | 9 (4.3) | 197 (95.2) | 157 (75.8) | ||
| Blood group, n (%) | |||||||
| O | 195 | 1 (0.5) | 9 (4.6) | 186 (94.8) | .7162 | 154 (79.4) | .6641 |
| Non-O | 118 | 0 (0) | 3 (2.5) | 115 (97.5) | 96 (81.4) | ||
| Age (y), n (%) | |||||||
| <18 | 125 | 0 (0) | 10 (8.0) | 115 (92.0) | .0159 | 93 (74.4) | .1768 |
| ≥18 | 236 | 1 (0.4) | 5 (2.1) | 230 (97.5) | 191 (80.9) | ||
| Body weight (kg), n (%) | |||||||
| ≤35 | 72 | 0 (0) | 6 (8.3) | 66 (91.7) | .3182 | 51 (70.8) | .0180 |
| 35-70 | 271 | 1 (0.4) | 9 (3.3) | 246 (90.8) | 201 (74.2) | ||
| >70 | 18 | 0 (0) | 0 (0) | 18 (100.0) | 18 (100.0) | ||
| DDAVP doses (μg/kg), n (%) | |||||||
| ≤0.3 | 263 | 1 (0.4) | 13 (4.9) | 249 (94.7) | .6476 | 201 (76.4) | .2258 |
| >0.3 | 83 | 0 (0) | 2 (2.4) | 81 (97.6) | 69 (83.1) | ||
| AR . | |||||||
|---|---|---|---|---|---|---|---|
| . | Total . | Absent . | Partial . | Complete . | P value . | Complete ≥0.8 . | P value . |
| F8 variants, n (%) | |||||||
| Null | 143 | 1 (0.7) | 11 (7.7) | 130 (90.9) | .0059 | 102 (71.3) | .0092 |
| Non-null | 218 | 0 (0) | 4 (1.8) | 214 (98.2) | 181 (83.0) | ||
| Severity of the familial HA, n (%) | |||||||
| Severe/moderate | 216 | 1 (0.5) | 13 (6.0) | 202 (93.5) | .0416 | 160 (74.1) | .0091 |
| 124 (85.5) | |||||||
| Mild | 145 | 0 (0) | 2 (1.4) | 143 (98.6) | |||
| Basal VWF levels (IU/mL), n (%) | |||||||
| <0.7 | 127 | 0 (0) | 4 (3.1) | 123 (96.9) | .8592 | 103 (81.1) | .2804 |
| ≥0.7 | 207 | 1 (0.5) | 9 (4.3) | 197 (95.2) | 157 (75.8) | ||
| Blood group, n (%) | |||||||
| O | 195 | 1 (0.5) | 9 (4.6) | 186 (94.8) | .7162 | 154 (79.4) | .6641 |
| Non-O | 118 | 0 (0) | 3 (2.5) | 115 (97.5) | 96 (81.4) | ||
| Age (y), n (%) | |||||||
| <18 | 125 | 0 (0) | 10 (8.0) | 115 (92.0) | .0159 | 93 (74.4) | .1768 |
| ≥18 | 236 | 1 (0.4) | 5 (2.1) | 230 (97.5) | 191 (80.9) | ||
| Body weight (kg), n (%) | |||||||
| ≤35 | 72 | 0 (0) | 6 (8.3) | 66 (91.7) | .3182 | 51 (70.8) | .0180 |
| 35-70 | 271 | 1 (0.4) | 9 (3.3) | 246 (90.8) | 201 (74.2) | ||
| >70 | 18 | 0 (0) | 0 (0) | 18 (100.0) | 18 (100.0) | ||
| DDAVP doses (μg/kg), n (%) | |||||||
| ≤0.3 | 263 | 1 (0.4) | 13 (4.9) | 249 (94.7) | .6476 | 201 (76.4) | .2258 |
| >0.3 | 83 | 0 (0) | 2 (2.4) | 81 (97.6) | 69 (83.1) | ||