Multivariable logistic regression for complete remission as best response
| Characteristic . | OR . | 95% CI . | P value . |
|---|---|---|---|
| BMI change 3 mo before CAR | |||
| No weight loss | — | — | |
| Weight loss | 0.39 | 0.19-0.79 | .009 |
| Disease subtypes | |||
| Large BCL | — | — | |
| Mantle cell lymphoma | 3.29 | 0.96-15.4 | .083 |
| Follicular lymphoma | 1.75 | 0.36-13.6 | .5 |
| Age at CAR T-cell infusion | 1.02 | 0.80-1.30 | .8 |
| Sex | |||
| Male | — | — | |
| Female | 1.67 | 0.84-3.39 | .15 |
| Karnofsky performance status | |||
| ≥90 | — | — | |
| <90 | 0.79 | 0.38-1.61 | .5 |
| LDH before lymphodepletion | 0.92 | 0.78-1.07 | .3 |
| Stable/progressive disease at the time of CAR | 0.61 | 0.30-1.20 | .2 |
| CRP before lymphodepletion | 0.90 | 0.81-1.00 | .051 |
| CAR T-cell costimulatory domain | |||
| CD28 | — | — | |
| 41BB | 0.56 | 0.28, 1.10 | .10 |
| Characteristic . | OR . | 95% CI . | P value . |
|---|---|---|---|
| BMI change 3 mo before CAR | |||
| No weight loss | — | — | |
| Weight loss | 0.39 | 0.19-0.79 | .009 |
| Disease subtypes | |||
| Large BCL | — | — | |
| Mantle cell lymphoma | 3.29 | 0.96-15.4 | .083 |
| Follicular lymphoma | 1.75 | 0.36-13.6 | .5 |
| Age at CAR T-cell infusion | 1.02 | 0.80-1.30 | .8 |
| Sex | |||
| Male | — | — | |
| Female | 1.67 | 0.84-3.39 | .15 |
| Karnofsky performance status | |||
| ≥90 | — | — | |
| <90 | 0.79 | 0.38-1.61 | .5 |
| LDH before lymphodepletion | 0.92 | 0.78-1.07 | .3 |
| Stable/progressive disease at the time of CAR | 0.61 | 0.30-1.20 | .2 |
| CRP before lymphodepletion | 0.90 | 0.81-1.00 | .051 |
| CAR T-cell costimulatory domain | |||
| CD28 | — | — | |
| 41BB | 0.56 | 0.28, 1.10 | .10 |
CI, confidence interval; OR, odds ratio.