Etiologies
| Etiology . | n . | (%) . | Comment . |
|---|---|---|---|
| Malignancies | 22 | (35) | |
| Myeloid | 2 | (3) | |
| AML | 1 | (2) | |
| MDS | 1 | (2) | |
| B-lymphoid | 11 | (18) | |
| Hodgkin lymphoma | 4 | (6) | EBV association n = 4 |
| DLBCL | 3 | (5) | EBV association n = 2 |
| B-cell lymphoma | 1 | (2) | |
| Primarily cerebral B-cell lymphoma | 1 | (2) | |
| Multiple myeloma | 2 | (3) | After autologous SCT n = 2 |
| T/NK-lymphoid | 8 | (13) | |
| T/NK-cell lymphoma | 2 | (3) | |
| PTCL-NOS | 2 | (3) | |
| Angioimmunoblastic T-cell lymphoma | 1 | (2) | EBV association |
| Mycosis fungoides | 1 | (2) | |
| NK-cell leukemia | 1 | (2) | EBV association |
| T-cell neoplasia (not further classified) | 1 | (2) | |
| Clinical suspicion of lymphoma | 1 | (2) | |
| Infections | 22 | (35) | |
| Viral | 16 | (26) | |
| EBV | 12 | (19) | After SCT n = 1 |
| CMV | 3 | (5) | After SCT n = 1 |
| HHV-6 | 1 | (2) | |
| Bacteria | 3 | (5) | |
| Escherichia coli | 1 | (2) | |
| Streptococcus agalactiae | 1 | (2) | |
| Streptococcus pyogenes | 1 | (2) | |
| Fungal | 2 | (3) | |
| Aspergillus fumigatus | 1 | (2) | Viral coinfection suspected |
| Candida glabrata | 1 | (2) | After urosepsis (Klebsiella spp.) |
| Unknown/multiple | 1 | (2) | |
| Autoimmune/systemic | 10 | (16) | |
| AOSD | 5 | (8) | |
| Antisynthetase syndrome | 2 | (3) | |
| Hypereosinophilic syndrome | 1 | (2) | |
| Immune complex vasculitis | 1 | (2) | |
| Sweet syndrome | 1 | (2) | |
| Idiopathic | 8 | (13) |
| Etiology . | n . | (%) . | Comment . |
|---|---|---|---|
| Malignancies | 22 | (35) | |
| Myeloid | 2 | (3) | |
| AML | 1 | (2) | |
| MDS | 1 | (2) | |
| B-lymphoid | 11 | (18) | |
| Hodgkin lymphoma | 4 | (6) | EBV association n = 4 |
| DLBCL | 3 | (5) | EBV association n = 2 |
| B-cell lymphoma | 1 | (2) | |
| Primarily cerebral B-cell lymphoma | 1 | (2) | |
| Multiple myeloma | 2 | (3) | After autologous SCT n = 2 |
| T/NK-lymphoid | 8 | (13) | |
| T/NK-cell lymphoma | 2 | (3) | |
| PTCL-NOS | 2 | (3) | |
| Angioimmunoblastic T-cell lymphoma | 1 | (2) | EBV association |
| Mycosis fungoides | 1 | (2) | |
| NK-cell leukemia | 1 | (2) | EBV association |
| T-cell neoplasia (not further classified) | 1 | (2) | |
| Clinical suspicion of lymphoma | 1 | (2) | |
| Infections | 22 | (35) | |
| Viral | 16 | (26) | |
| EBV | 12 | (19) | After SCT n = 1 |
| CMV | 3 | (5) | After SCT n = 1 |
| HHV-6 | 1 | (2) | |
| Bacteria | 3 | (5) | |
| Escherichia coli | 1 | (2) | |
| Streptococcus agalactiae | 1 | (2) | |
| Streptococcus pyogenes | 1 | (2) | |
| Fungal | 2 | (3) | |
| Aspergillus fumigatus | 1 | (2) | Viral coinfection suspected |
| Candida glabrata | 1 | (2) | After urosepsis (Klebsiella spp.) |
| Unknown/multiple | 1 | (2) | |
| Autoimmune/systemic | 10 | (16) | |
| AOSD | 5 | (8) | |
| Antisynthetase syndrome | 2 | (3) | |
| Hypereosinophilic syndrome | 1 | (2) | |
| Immune complex vasculitis | 1 | (2) | |
| Sweet syndrome | 1 | (2) | |
| Idiopathic | 8 | (13) |
AML, acute myelogenous leukemia; AOSD, adult-onset Still’s disease; CMV, cytomegalovirus; DLBCL, diffuse large B-cell lymphoma; HHV-6, human herpesvirus 6; MDS, myelodysplastic syndrome; PTCL-NOS, peripheral T-cell lymphoma not otherwise specified.