Outcomes according to the 4 risk scores
| . | Complete remission . | POD24 . | PFS at 6 y . | OS at 6 y . | ||||
|---|---|---|---|---|---|---|---|---|
| n/total (%) . | P . | n/total (%) . | P . | % (95% confidence interval) . | P . | % (95% confidence interval) . | P . | |
| 91/108 (84.5) . | NA . | 22/108 (20.4) . | NA . | 60.5 (51.6-70.9) . | NA . | 88.2 (82.0-94.7) . | NA . | |
| FLIPI score | 0.029 | 0.013 | 0.00072 | 0.00057 | ||||
| 0-2 | 57/63 (90.5) | 8/63 (12.7) | 71.9 (60.7-85.1) | 100 | ||||
| 3-5 | 30/41 (73.2) | 14/41 (34.1) | 39.3 (26.8-57.7) | 70.6 (57.9-86.2) | ||||
| FLIPI-2 score | 0.591 | 1 | 0.35 | 0.046 | ||||
| 0-2 | 51/60 (85.0) | 13/60 (21.7) | 61.7 (50.0-76.2) | 92.8 (86.1-100) | ||||
| 3-5 | 32/40 (80.0) | 9/40 (22.5) | 53.3 (39.5-71.9) | 79.1 (67.1-93.2) | ||||
| PRIMA-PI score | 0.145 | 1 | 0.21 | 0.17 | ||||
| Low-intermediate | 58/66 (87.9) | 13/66 (19.7) | 61.1 (49.8-75.0) | 91.5 (84.6-99.0) | ||||
| High | 24/32 (75.0) | 7/32 (21.9) | 52.3 (37.1-73.5) | 77.9 (64.6-93.9) | ||||
| m7-FLIPI score | 0.065 | 0.392 | 0.076 | 0.06 | ||||
| Low | 70/80 (87.5) | 15/80 (18.8) | 62.7 (52.4-75.1) | 92.0 (86.0-98.4) | ||||
| High | 17/24 (70.8) | 7/24 (29.2) | 45.8 (29-7-70.8) | 74.1 (58.1-94.4) | ||||
| . | Complete remission . | POD24 . | PFS at 6 y . | OS at 6 y . | ||||
|---|---|---|---|---|---|---|---|---|
| n/total (%) . | P . | n/total (%) . | P . | % (95% confidence interval) . | P . | % (95% confidence interval) . | P . | |
| 91/108 (84.5) . | NA . | 22/108 (20.4) . | NA . | 60.5 (51.6-70.9) . | NA . | 88.2 (82.0-94.7) . | NA . | |
| FLIPI score | 0.029 | 0.013 | 0.00072 | 0.00057 | ||||
| 0-2 | 57/63 (90.5) | 8/63 (12.7) | 71.9 (60.7-85.1) | 100 | ||||
| 3-5 | 30/41 (73.2) | 14/41 (34.1) | 39.3 (26.8-57.7) | 70.6 (57.9-86.2) | ||||
| FLIPI-2 score | 0.591 | 1 | 0.35 | 0.046 | ||||
| 0-2 | 51/60 (85.0) | 13/60 (21.7) | 61.7 (50.0-76.2) | 92.8 (86.1-100) | ||||
| 3-5 | 32/40 (80.0) | 9/40 (22.5) | 53.3 (39.5-71.9) | 79.1 (67.1-93.2) | ||||
| PRIMA-PI score | 0.145 | 1 | 0.21 | 0.17 | ||||
| Low-intermediate | 58/66 (87.9) | 13/66 (19.7) | 61.1 (49.8-75.0) | 91.5 (84.6-99.0) | ||||
| High | 24/32 (75.0) | 7/32 (21.9) | 52.3 (37.1-73.5) | 77.9 (64.6-93.9) | ||||
| m7-FLIPI score | 0.065 | 0.392 | 0.076 | 0.06 | ||||
| Low | 70/80 (87.5) | 15/80 (18.8) | 62.7 (52.4-75.1) | 92.0 (86.0-98.4) | ||||
| High | 17/24 (70.8) | 7/24 (29.2) | 45.8 (29-7-70.8) | 74.1 (58.1-94.4) | ||||
Complete remission and POD24 was not calculable in 1 patient. Risk stratification could not be calculated in 4, 8, 10, and 4 patients for the FLIPI, FLIPI-2, PRIMA-PI, and m7-FLIPI scores, respectively.
NA, not applicable.