Table 2. aPTT reagent sensitivity to... | American Society of Hematology

Table 2.

aPTT reagent sensitivity to progressive single FVIII deficiency or pan-deficiency of all factors

FVIII activity, %	aPTT, s^*	All factor activity, %	aPTT, s^*
100	28.6	100	29.4
90	28.6	90	30.1
80	29.6	80	31.9
70	30.7	70	33.9^**
60	31.5	60	37.4^**
50	32.5	50	43.0
40	34.3^**	40	51.9
30	36.1^**	30	69.9
20	39.1	20	108.0
15	40.5	15	No clot
10	44.5	10	No clot
5	49.6	5	No clot
1	61.1	1	No clot
0.001	79.6	0.001	No clot

FVIII activity, %	aPTT, s^*	All factor activity, %	aPTT, s^*
100	28.6	100	29.4
90	28.6	90	30.1
80	29.6	80	31.9
70	30.7	70	33.9^**
60	31.5	60	37.4^**
50	32.5	50	43.0
40	34.3^**	40	51.9
30	36.1^**	30	69.9
20	39.1	20	108.0
15	40.5	15	No clot
10	44.5	10	No clot
5	49.6	5	No clot
1	61.1	1	No clot
0.001	79.6	0.001	No clot

Reference interval for this aPTT reagent (24-35 seconds).

The bold font indicates when the aPTT seconds begin to exceed the reference interval.