Table 2.

Operating characteristics of the Aspergillus GM EIA and BDG assay for surveillance testing in pediatric patients with cancer or undergoing HCT

Author, yearStudy cohort sizeStudy's IFD incidence rateSensitivitySpecificityPPVNPV
Aspergillus GM EIA 
Hovi et al34  98 8.0% 93% 50% 14% 99% 
Steinbach et al35  64 0% 87% 0% 0% 98% 
Hayden et al36  56 30.4% 87% 65% 69% 85% 
Badiee et al37  62 16.1% 92% 90% 82% 96% 
Koltze et al38  34 17.6% 100% 83% 100% 97% 
Fisher et al26  425 0.7% 0% 98.8% 0% 99.9% 
BDG assay 
Badiee et al37  62 16.1% 46% 50% 26% 71% 
Koltze et al38  34 17.6% 29% 83% 20% 89% 
Fisher et al26  425 1.4% 0% 94.7% 0% 99.8% 
Author, yearStudy cohort sizeStudy's IFD incidence rateSensitivitySpecificityPPVNPV
Aspergillus GM EIA 
Hovi et al34  98 8.0% 93% 50% 14% 99% 
Steinbach et al35  64 0% 87% 0% 0% 98% 
Hayden et al36  56 30.4% 87% 65% 69% 85% 
Badiee et al37  62 16.1% 92% 90% 82% 96% 
Koltze et al38  34 17.6% 100% 83% 100% 97% 
Fisher et al26  425 0.7% 0% 98.8% 0% 99.9% 
BDG assay 
Badiee et al37  62 16.1% 46% 50% 26% 71% 
Koltze et al38  34 17.6% 29% 83% 20% 89% 
Fisher et al26  425 1.4% 0% 94.7% 0% 99.8% 

Data in this table adapted from Lehrnbecher et al, Table 3.25 

or Create an Account

Close Modal
Close Modal