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Journal Articles

The role of microbial metabolites in fecal microbiota transplantation in patients with acute gvhd of the gut

Blood (2025) 146 (Supplement 1): 4236.

https://doi.org/10.1182/blood-2025-4236

Published: 2025

Journal Articles

Timed inhibition of the sting pathway improves tissue regeneration and prevents GVHD following allo-HSCT

Sascha Göttert, Chiara Suriano, Omer Khalid, Paul Heinrich, Sakhila Ghimire, Eva Vonbrunn, Elisabeth Meedt, Petra Hoffmann, Matthias Edinger, Daniela Weber, Daniel Wolff, Michael Rehli, Maike Büttner-Herold, Wolfgang Herr, Ernst Holler, Christian Schmidl, Hendrik Poeck

Blood (2025) 146 (Supplement 1): 2317.

https://doi.org/10.1182/blood-2025-2317

Published: 2025

Journal Articles

Multi-faceted influence of immunomodulatory metabolites on CAR-T cell therapy

Dhyani Shah, Markus Perl, Matthias Fante, Severin Guetter, Simon Holzinger, Luisa-Marie Becker, Misbah Tariq, Philipp Meanauer, Simon Delahais, Gloria Lutzny-Geier, Julian Scherer, Sascha Goettert, Konstantin Herfeld, Paul Heinrich, Klaus-Georg Kreitmeier, Wolfgang Herr, Janina Doerr, Dennis Harrer, Leo Hansmann, Marcel Trefny, Matthias Edinger, Daniel Wolff, Daniela Weber, Elisabeth Meedt, André Gessner, Ernst Holler, Tobias Wertheimer, Klaus Neuhaus, Tingting Zheng, Kai Ziegler-Martin, David M. Cordas Dos Santos, Sebastian Theurich, Melanie Schirmer, Jonas Schluter, Michael Schmitt, Karin Kleigrewe, Markus Feuerer, Christoph Heuser-Loy, Jeremy Baldwin, Michael Hudecek, Luca Gattinoni, Marion Subklewe, Viktoria Blumenberg, Maria-Luisa Schubert, Christoph Stein-Thoeringer, Maik Luu, Sebastian Kobold, Erik Thiele Orberg, Hendrik Poeck

Blood (2025) 146 (Supplement 1): 2343.

https://doi.org/10.1182/blood-2025-2343

Published: 2025

Journal Articles

Mucosal calprotectin is associated with severity of aGI-GVHD and poor outcomes after allogeneic stem cell transplantation

Blood blood.2025029402.

https://doi.org/10.1182/blood.2025029402

Published: 2025

Includes: Supplemental data

Journal Articles

Loss of Microbiota-Derived Metabolites Is Associated with Mucosal-Barrier-Injury Bloodstream Infection in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Blood (2024) 144 (Supplement 1): 4904.

https://doi.org/10.1182/blood-2024-193273

Published: 2024

Journal Articles

Developing Evidence-Based Guidelines for Optimal Patient Communication Prior and Post Allogeneic Stem Cell Transplantation

Anne Herrmann, Helene Schoemans, Eva Wilhelm, Guy Tavori, Nada Hamad, Meredith A. Cowden, Anna Barata, Francis A. Ayuk, Wolfgang Herr, Joerg Halter, Stephanie Lee, Daniel Wolff

Blood (2024) 144 (Supplement 1): 4917.

https://doi.org/10.1182/blood-2024-199052

Published: 2024

Journal Articles

Allogeneic Hematopoietic Cell Transplantation Promotes Atherosclerosis in Mice Driven By Donor CD8+ T Cells

Haroon Shaikh, Ivana Jorgacevic, Hla Ali, Maja Bundalo, Sarah Schäfer, Michael AG Kern, Maike Büttner- Herold, Clément Cochain, Antoine-Emmanuel Saliba, Giuseppe Rizzo, Juan Vargas, Louis Boon, Wolfgang Herr, Hermann Einsele, Friederike Berberich-Siebelt, Andreas Rosenwald, Andreas Beilhack, Alma Zernecke

Blood (2024) 144 (Supplement 1): 3402.

https://doi.org/10.1182/blood-2024-194190

Published: 2024

Journal Articles

Recovery of the Intestinal Microbiome in Patients at Day +100 after Allogeneic Stem Cell Transplantation Is Defined By Microbial Metabolite Profiles and Linked to Long-Term Outcomes

Blood (2024) 144 (Supplement 1): 780.

https://doi.org/10.1182/blood-2024-199035

Published: 2024

Journal Articles

Immunomodulatory Microbial Metabolites Protect Against Graft-Vs-Host Disease and Enhance Anti-Leukemia Responses in Mice and Patients Receiving Stem Cell Transplantation

Sascha Göttert, Erik Thiele-Orberg, Kaiji Fan, Paul Heinrich, Daniel Wolff, Daniela Weber, Florian Bassermann, Petra Hoffmann, Matthias Edinger, Natalie Koehler, André Gessner, Wolfgang Herr, Simon M Heidegger, Ernst Holler, Hendrik Poeck

Blood (2024) 144 (Supplement 1): 264.

https://doi.org/10.1182/blood-2024-205921

Published: 2024

Journal Articles

Virus-reactive T cells expanded in aplastic anemia eliminate hematopoietic progenitor cells by molecular mimicry

Blood (2024) 143 (14): 1365–1378.

https://doi.org/10.1182/blood.2023023142

Published: 2024

Includes: Supplemental data

Journal Articles

Tocilizumab Administration in CAR-T Cell Associated Cytokine Release Syndrome Induces Hypofibrinogenemia

Markus Perl, Konstantin Herfeld, Dennis Harrer, Matthias Hoepting, Marina Schweiger, Ulrich Sterz, Leonard Knoedler, Leo Hansmann, Wolfgang Herr, Hendrik Poeck, Daniel Wolff, Matthias Edinger, Christina Hart, Matthias Fante

Blood (2023) 142 (Supplement 1): 5493.

https://doi.org/10.1182/blood-2023-186878

Published: 2023

Journal Articles

Bacterial and Bacteriophage Consortia Are Associated with Protective Intestinal Immuno-Modulatory Metabolites in Allogeneic Stem Cell Transplantation Patients

Blood (2023) 142 (Supplement 1): 477.

https://doi.org/10.1182/blood-2023-172457

Published: 2023

Journal Articles

Identification of Bacterial and Viral Consortia for the Production of Intestinal Microbiota-Derived Metabolites Associated with Protection in Allogeneic Stem Cell Transplantation Patients

Blood (2022) 140 (Supplement 1): 7619–7621.

https://doi.org/10.1182/blood-2022-157423

Published: 2022

Journal Articles

Effects of Bacterial Metabolites on CAR-T Cell Therapy

Luisa Becker, Markus Perl, Leonard Knödler, Wolfgang Herr, Hendrik Poeck

Blood (2022) 140 (Supplement 1): 12703.

https://doi.org/10.1182/blood-2022-169496

Published: 2022

Journal Articles

Expansion of Plasmablasts at Day 90 after Allogeneic Stem Cell Transplantation Predict Chronic Gvhd

Katharina M. Habenicht, Anna Bootz, Simon Schäfer, Ingrid Vasova, Matthias Fante, Andrea Schneider, Michael Rehli, Petra Hoffmann, Wolf Roesler, Matthias Edinger, Wolfgang Herr, Andreas Mackensen, Daniel Wolff, Julia Winkler, Thomas H. Winkler

Blood (2022) 140 (Supplement 1): 4776–4777.

https://doi.org/10.1182/blood-2022-165915

Published: 2022

Journal Articles

Immunomodulatory Microbial Metabolites Identified in Allo-SCT Patients Protect from GvHD By Sting Dependent Modulation of Intestinal Tissue Homeostasis

Sascha Göttert, Erik Thiele-Orberg, Kaiji Fan, Sakhila Ghimire, Paul Heinrich, Wolfgang Herr, Simon Heidegger, Ernst Holler, Hendrik Poeck

Blood (2022) 140 (Supplement 1): 7336–7337.

https://doi.org/10.1182/blood-2022-169118

Published: 2022

Journal Articles

Cohesin-STAG2 Mutations Alter Chromatin Structure and Gene Regulation in Human Acute Myeloid Leukemia

Alexander Fischer, Roger Mulet-Lazaro, Margit Nützel, Stanley van Herk, Hanna Stanewsky, Ute Ackermann, Edith Reuschel, Nicholas Strieder, Inmaculada Hernandez-Lopez, Wolfgang Herr, Peter J.M. Valk, Michael Rehli, Ruud Delwel, Claudia Gebhard

Blood (2022) 140 (Supplement 1): 3379–3380.

https://doi.org/10.1182/blood-2022-162219

Published: 2022

Journal Articles

Overcoming CAR-T Cell Exhaustion and Improving Antitumoral Efficacy in Hematologic Neoplasms Utilizing CRISPR/Cas9 Technology

Leonard Knoedler, Markus Perl, Luisa Becker, Hendrik Poeck, Christian Schmidl, Wolfgang Herr

Blood (2022) 140 (Supplement 1): 12701–12702.

https://doi.org/10.1182/blood-2022-167369

Published: 2022

Journal Articles

Microbial-Derived Metabolites Induce Epithelial Recovery Via the Sting Pathway in Mice and Men and Protect from Graft-Versus-Host Disease

Erik Thiele Orberg, Sascha Göttert, Andreas Hiergeist, Elisabeth Meedt, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, Andre Gessner, Ernst Holler, Simon Heidegger, Hendrik Poeck

Blood (2021) 138 (Supplement 1): 87.

https://doi.org/10.1182/blood-2021-147794

Published: 2021

Journal Articles

Longitudinal Analysis of Gut Bacteriome, Mycobiome, Virome and Metabolome in Allogeneic Stem Cell Transplantation Reveals Susceptibility for Acute Graft-Versus-Host Disease

Blood (2021) 138 (Supplement 1): 332.

https://doi.org/10.1182/blood-2021-153026

Published: 2021

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The role of microbial metabolites in fecal microbiota transplantation in patients with acute gvhd of the gut

Timed inhibition of the sting pathway improves tissue regeneration and prevents GVHD following allo-HSCT

Multi-faceted influence of immunomodulatory metabolites on CAR-T cell therapy

Mucosal calprotectin is associated with severity of aGI-GVHD and poor outcomes after allogeneic stem cell transplantation

Loss of Microbiota-Derived Metabolites Is Associated with Mucosal-Barrier-Injury Bloodstream Infection in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Developing Evidence-Based Guidelines for Optimal Patient Communication Prior and Post Allogeneic Stem Cell Transplantation

Allogeneic Hematopoietic Cell Transplantation Promotes Atherosclerosis in Mice Driven By Donor CD8+ T Cells

Recovery of the Intestinal Microbiome in Patients at Day +100 after Allogeneic Stem Cell Transplantation Is Defined By Microbial Metabolite Profiles and Linked to Long-Term Outcomes

Immunomodulatory Microbial Metabolites Protect Against Graft-Vs-Host Disease and Enhance Anti-Leukemia Responses in Mice and Patients Receiving Stem Cell Transplantation

Virus-reactive T cells expanded in aplastic anemia eliminate hematopoietic progenitor cells by molecular mimicry

Tocilizumab Administration in CAR-T Cell Associated Cytokine Release Syndrome Induces Hypofibrinogenemia

Bacterial and Bacteriophage Consortia Are Associated with Protective Intestinal Immuno-Modulatory Metabolites in Allogeneic Stem Cell Transplantation Patients

Identification of Bacterial and Viral Consortia for the Production of Intestinal Microbiota-Derived Metabolites Associated with Protection in Allogeneic Stem Cell Transplantation Patients

Effects of Bacterial Metabolites on CAR-T Cell Therapy

Expansion of Plasmablasts at Day 90 after Allogeneic Stem Cell Transplantation Predict Chronic Gvhd

Immunomodulatory Microbial Metabolites Identified in Allo-SCT Patients Protect from GvHD By Sting Dependent Modulation of Intestinal Tissue Homeostasis

Cohesin-STAG2 Mutations Alter Chromatin Structure and Gene Regulation in Human Acute Myeloid Leukemia

Overcoming CAR-T Cell Exhaustion and Improving Antitumoral Efficacy in Hematologic Neoplasms Utilizing CRISPR/Cas9 Technology

Microbial-Derived Metabolites Induce Epithelial Recovery Via the Sting Pathway in Mice and Men and Protect from Graft-Versus-Host Disease

Longitudinal Analysis of Gut Bacteriome, Mycobiome, Virome and Metabolome in Allogeneic Stem Cell Transplantation Reveals Susceptibility for Acute Graft-Versus-Host Disease

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American Society of Hematology

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