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Journal Articles

The role of BCL-6 in HBV positive diffuse large B-cell lymphoma

Hanying Shen, Linyan Xu, Wei Chen, Zhenyu Li, Kailin Xu, Feng Zhu

Blood (2025) 146 (Supplement 1): 7078.

https://doi.org/10.1182/blood-2025-7078

Published: 2025

Journal Articles

Wildtype NUP98 cooperates with NPM1c to drive oncogenic transcription

Sara Gama, Marcel Müller, Hannah González Dammers, Elena Haarer, Sara Peruzzi, José Gonçalves-Dias, Jan-Henning Klusmann, Lu Yang, Renee Chen, Chun-Wei Chen, Stamatis Papathanasiou, Brunangelo Falini, Lorenzo Brunetti, Hannah Uckelmann

Blood (2025) 146 (Supplement 1): 865.

https://doi.org/10.1182/blood-2025-865

Published: 2025

Journal Articles

CRISPR-tica.ai: A function-informed generative modeling pipeline for prioritizing drug discovery in AML

Dhvani Vora, Anthony Chan, Sheela Pangeni Pokharel, Qiao Liu, Renee Chen, Bryan Chen, April Chen, Lu Yang, Chun-Wei Chen

Blood (2025) 146 (Supplement 1): 277.

https://doi.org/10.1182/blood-2025-277

Published: 2025

Journal Articles

Pharmacological targeting of CTPS1 elicits macrophage-mediated anti-leukemia immunity

Meng Liu, Lei Zhang, Xin He, Haojie Dong, Yang Li, Shuaishuai Ge, Guohua Wu, Umesh Yadav, wei chen, Pinghui Feng, Guido Marcucci, Ling Li

Blood (2025) 146 (Supplement 1): 1490.

https://doi.org/10.1182/blood-2025-1490

Published: 2025

Journal Articles

Targeting adss overcomes venetoclax resistance in TP53-mutated acute myeloid leukemia

Blood (2025) 146 (Supplement 1): 213.

https://doi.org/10.1182/blood-2025-213

Published: 2025

Journal Articles

DDX6 undergoes phase separation to modulate metabolic plasticity and chemoresistance

Blood (2025) 146 (Supplement 1): 212.

https://doi.org/10.1182/blood-2025-212

Published: 2025

Journal Articles

Mitochondrial RNA pseudouridine reprograms metabolism and induces immunosuppression in myeloid leukemia

Blood (2025) 146 (Supplement 1): 211.

https://doi.org/10.1182/blood-2025-211

Published: 2025

Journal Articles

The KMT2A-PTD oncoprotein depends on ENL but not menin to drive AML gene expression

Daniela Wenge, Maria Wessels, Sydney Schweber, Meaghan Boileau, Christian Marinaccio, Wallace Bourgeois, Charles Hatton, Laura Godfrey, Yufan Shan, Thatcher Akele, Yanhe Wen, Jennifer Perry, Adrienne Dorrance, Omar Abdel-Wahab, Chun-Wei Chen, Michael Erb, Scott Armstrong

Blood (2025) 146 (Supplement 1): 321.

https://doi.org/10.1182/blood-2025-321

Published: 2025

Journal Articles

Targeting the METTL1/m7G axis as a therapeutic strategy in myeloid leukemia

Blood (2025) 146 (Supplement 1): 2539.

https://doi.org/10.1182/blood-2025-2539

Published: 2025

Journal Articles

Therapeutic effect of menin inhibitors is reversible in AML treatment and could be enhanced by the targeting of differentiation associated chromatin complex

Zhong Fan, John Mosior, Yanan Jiang, Jin Wang, Chun-Wei Chen, Xiaotian Zhang

Blood (2025) 146 (Supplement 1): 3295.

https://doi.org/10.1182/blood-2025-3295

Published: 2025

Journal Articles

Stepwise leukemogenesis and therapeutic targets revealed in B-cell acute lymphoblastic leukemia driven by PAX5 mutations

Zhilian Jia, Zunsong Hu, Lu Yang, Anthony Chan, Xiaohua Huang, Allen Mao, Ibrahim Aldoss, Lucy Ghoda, Michelle Afkhami, Guido Marcucci, Zhenhua Chen, Jianjun Chen, Chun-Wei Chen, Shai Izraeli, Markus Müschen, Nora Heisterkamp, Zhaohui Gu

Blood (2025) 146 (Supplement 1): 139.

https://doi.org/10.1182/blood-2025-139

Published: 2025

Journal Articles

circFUT8 promotes proplatelet formation by interacting with IGF2BP2 and stabilizing TNS1 mRNA in megakaryocytes

Huang Wu, Yao Lu, Denglian Sun, Zeqing Miao, Siyuan Chen, Wenjun Xia, Yanhua Chen, Yun Yu, Weiwei Zhang, Wei Chen, David Stegner, Su Hao Lo, Aiqing Wen

Blood (2025) 146 (17): 2119–2132.

https://doi.org/10.1182/blood.2025028527

Published: 2025

Includes: Supplemental data

Journal Articles

Genetic and epigenetic mechanisms of GPRC5D loss after anti-GPRC5D CAR T-cell therapy in multiple myeloma

Blood (2025) 146 (2): 178–190.

https://doi.org/10.1182/blood.2024026622

Published: 2025

Includes: Supplemental data

Journal Articles

Safety and Feasibility of a 41BB Co-Stimulated CD19 CAR-NK Cell Therapy in Refractory/Relapsed Large B-Cell Lymphoma

Wenbin Qian, Wen Lei, Hui Liu, Wei Chen, Yun Liang, Yi Eve Sun, Xiangmin Tong, Aibin Liang

Blood (2024) 144 (Supplement 1): 7209.

https://doi.org/10.1182/blood-2024-202988

Published: 2024

Journal Articles

Red Blood Cell Pyruvate Kinase Properties in Sickle Cell Disease - of Mice and Men

Marissa J.M. Traets, Brigitte A. van Oirschot, Titine J.J. Ruiter, Charles Levine, Anita W. Rijneveld, Judith J.M. Jans, Minke A.E. Rab, Yu-Wei Chen, Richard van Wijk

Blood (2023) 142 (Supplement 1): 1115.

https://doi.org/10.1182/blood-2023-173572

Published: 2023

Journal Articles

Deciphering Metabolomic Signatures Associated with Sickle Cell Disease Using Mouse Models

Claudia Montllor-Albalate, Alka A Potdar, Yu-Wei Chen, Francis DeGuzman, G. Karen Yu

Blood (2023) 142 (Supplement 1): 2484.

https://doi.org/10.1182/blood-2023-178709

Published: 2023

Journal Articles

Selective Support of CAR-T Cell Therapies By Cis-Targeted IL-2 or IL-21 Cytokines Results in Enhanced Anti-Tumor Activity

Sara Sleiman, Nathan D Mathewson, Feng Shen, Kelly Moynihan, Wei Chen, Paul Bessette, Chris Kimberlin, Danielle Pappas, Terrence Park, Andy Yeung, Ivana Djuretic, Saar Gill

Blood (2022) 140 (Supplement 1): 10259–10260.

https://doi.org/10.1182/blood-2022-168411

Published: 2022

Journal Articles

Targeting PRMT9 Elicits Cgas-Mediated Anti-Leukemia Immunity

Blood (2022) 140 (Supplement 1): 4931–4933.

https://doi.org/10.1182/blood-2022-167366

Published: 2022

Journal Articles

Interpreting Immune Reconstitution and Clinical Outcome By Single-Cell Transcriptomic Analysis in T-ALL Patients Undergoing Donor-Derived CD7 CAR-T Immunotherapy

Hui Shi, Kai Hu, Fan Yang, Zhuojun Liu, Jia Liu, Wei Chen, Jian Yu

Blood (2022) 140 (Supplement 1): 10422–10423.

https://doi.org/10.1182/blood-2022-165035

Published: 2022

Journal Articles

Disruption of dNTP homeostasis by ribonucleotide reductase hyperactivation overcomes AML differentiation blockade

Blood (2022) 139 (26): 3752–3770.

https://doi.org/10.1182/blood.2021015108

Published: 2022

Includes: Supplemental data

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The role of BCL-6 in HBV positive diffuse large B-cell lymphoma

Wildtype NUP98 cooperates with NPM1c to drive oncogenic transcription

CRISPR-tica.ai: A function-informed generative modeling pipeline for prioritizing drug discovery in AML

Pharmacological targeting of CTPS1 elicits macrophage-mediated anti-leukemia immunity

Targeting adss overcomes venetoclax resistance in TP53-mutated acute myeloid leukemia

DDX6 undergoes phase separation to modulate metabolic plasticity and chemoresistance

Mitochondrial RNA pseudouridine reprograms metabolism and induces immunosuppression in myeloid leukemia

The KMT2A-PTD oncoprotein depends on ENL but not menin to drive AML gene expression

Targeting the METTL1/m7G axis as a therapeutic strategy in myeloid leukemia

Therapeutic effect of menin inhibitors is reversible in AML treatment and could be enhanced by the targeting of differentiation associated chromatin complex

Stepwise leukemogenesis and therapeutic targets revealed in B-cell acute lymphoblastic leukemia driven by PAX5 mutations

circFUT8 promotes proplatelet formation by interacting with IGF2BP2 and stabilizing TNS1 mRNA in megakaryocytes

Genetic and epigenetic mechanisms of GPRC5D loss after anti-GPRC5D CAR T-cell therapy in multiple myeloma

Safety and Feasibility of a 41BB Co-Stimulated CD19 CAR-NK Cell Therapy in Refractory/Relapsed Large B-Cell Lymphoma

Red Blood Cell Pyruvate Kinase Properties in Sickle Cell Disease - of Mice and Men

Deciphering Metabolomic Signatures Associated with Sickle Cell Disease Using Mouse Models

Selective Support of CAR-T Cell Therapies By Cis-Targeted IL-2 or IL-21 Cytokines Results in Enhanced Anti-Tumor Activity

Targeting PRMT9 Elicits Cgas-Mediated Anti-Leukemia Immunity

Interpreting Immune Reconstitution and Clinical Outcome By Single-Cell Transcriptomic Analysis in T-ALL Patients Undergoing Donor-Derived CD7 CAR-T Immunotherapy

Disruption of dNTP homeostasis by ribonucleotide reductase hyperactivation overcomes AML differentiation blockade

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American Society of Hematology

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