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Journal Articles

Overlap of post-CAR T HLH toxicity definitions and their prognostic significance in children and young adults with B-acute lymphoblastic leukemia

Free
Kevin McNerney, Soyang Kwon, Swati Naik, Vanessa Fabrizio, Gabriela Llaurador Caraballo, Lazaro Sanchez-Pinto, Aimee Talleur, Xiaopei Lily Zeng, Christina Baggott, Anant Vatsayan, Michael Verneris, Snehit Prabhu, Jenna Rossoff, Holly Pacenta, Christine Phillips, Julie-An Talano, Amy Moskop, Douglas Myers, Nicole Karras, Challice Bonifant, Muna Qayed, Prakash Satwani, William Temple, Christa Krupski, Amy Keating, Susanne Baumeister, Emily Egeler, Sharon Mavroukakis, Kevin Curran, Crystal Mackall, Theodore Laetsch, Rebecca Gardner, Liora Schultz
Journal: Blood
Blood (2025) 146 (Supplement 1): 4501.
https://doi.org/10.1182/blood-2025-4501
Published: 2025
Journal Articles

Peripheral blast count at apheresis as a risk factor for survival following tisagenlecleucel in children and young adults

Free
Kaylyn Lyons, Kristen Miller, Arpita Deb, Andrew Nicklawsky, Christina Baggott, Khanh Nguyen, Snehit Prabhu, Holly Pacenta, Christine Phillips, Jenna Rossoff, Heather Stefanski, Julie-An Talano, Amy Moskop, Amy Keating, Susanne Baumeister, Douglas Myers, Nicole Karras, Stacy Cooper, Muna Qayed, Michelle Hermiston, Prakash Satwani, Christa Krupski, Vasant Chinnabhandar, Crystal Mackall, Samuel John, Theodore Laetsch, Kevin Curran, Michael Verneris, Liora Schultz, Vanessa Fabrizio
Journal: Blood
Blood (2025) 146 (Supplement 1): 7638.
https://doi.org/10.1182/blood-2025-7638
Published: 2025
Journal Articles

CD22-CAR T cell multiomic features linked to patient outcomes in CD19-CAR resistant large B cell lymphoma

Free
Anne Marijn Kramer, Tara Murty, Yiyun Chen, Kameron Rodrigues, Mark Hamilton, Moksha Desai, Adam Kuo, Zachary Ehlinger, Warren Reynolds, Hrishikesh Srinagesh, Kristin Tsui, Skyler Rietberg, Kelvin Mo, John Baird, Yi-Jiun Su, Neha Agarwal, Elena Sotillo, Snehit Prabhu, Bita Sahaf, Saurabh Dahiya, Sneha Ramakrishna, Lori Muffly, Crystal Mackall, David Miklos, Zinaida Good, Matthew Frank
Journal: Blood
Blood (2025) 146 (Supplement 1): 566.
https://doi.org/10.1182/blood-2025-566
Published: 2025
Journal Articles

CD22-Directed CAR T Cell Single Cell Multiomic Features Associated with Immune Effector Cell-Associated Hemophagocytic Lymphohistiocytosis-like Syndrome (IEC-HS)

Free
Anne Marijn Kramer, Tara Murty, Yiyun Chen, Hrishikesh Srinagesh, Mark P. Hamilton, Kelvin C. Mo, Snehit Prabhu, Moksha Desai, Adam Kuo, Zachary Ehlinger, Warren D. Reynolds, John H. Baird, Yi-Jiun Su, Neha Agarwal, Bita Sahaf, Lori Muffly, Crystal L. Mackall, David B. Miklos, Matthew J. Frank, Zinaida Good
Journal: Blood
Blood (2024) 144 (Supplement 1): 911.
https://doi.org/10.1182/blood-2024-198688
Published: 2024
Journal Articles

CCL8/CCL13-Producing Tumor-Associated Macrophages Linked to Poor Outcomes after CAR T Cell Therapy for LBCL

Free
Kelvin C. Mo, Christine Y. Yeh, Mark P. Hamilton, Jay Spiegel, Moksha Desai, Zachary Ehlinger, Warren D. Reynolds, Eric Yang, Michael G. Ozawa, Yiyun Chen, Snehit Prabhu, Matthew J. Frank, Lori Muffly, Gursharan K. Claire, Sushma Bharadwaj, Saurabh Dahiya, Katherine A. Kong, Elena Sotillo, Bita Sahaf, Sylvia Plevritis, David B. Miklos, Crystal L. Mackall, Zinaida Good
Journal: Blood
Blood (2024) 144 (Supplement 1): 368.
https://doi.org/10.1182/blood-2024-198942
Published: 2024
Journal Articles

Role of B Cell Recovery in Relapse Risk and CD19 Phenotype Following Real-World Use of Tisagenlecleucel for Pediatric B-Acute Lymphoblastic Leukemia: A Multi-Institutional Retrospective Study

Free
Xiaopei Lily Zeng, Soyang Kwon, Anant Vatsayan, Christina Baggott, Snehit Prabhu, Samuel John, Holly L. Pacenta, Christine L. Phillips, Jenna Rossoff, Julie-An Talano, Amy Moskop, Michael R Verneris, Douglas D. Myers, Erin Marie Hall, Nicole A Karras, Challice L. Bonifant, Muna Qayed, Michelle L. Hermiston, Prakash Satwani, Christa Krupski, Amy K Keating, Susanne H.C. Baumeister, Vanessa A. Fabrizio, Vasant Chinnabhandar, Emily Egeler, Sharon Mavroukakis, Khanh Nguyen, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, Liora Michal Schultz, Kevin O. McNerney
Journal: Blood
Blood (2024) 144 (Supplement 1): 2817.
https://doi.org/10.1182/blood-2024-211231
Published: 2024
Journal Articles

Establishing Costs for Commercial Chimeric Antigen Receptor T-Cell (Tisagenlecleucel; Kymriah) in Children and Young Adult B-Cell Acute Lymphoblastic Leukemia; A Merged Analysis from the Prwcc and PHIS

Free
Prakash Satwani, Karen Chao, Maria Lopez-Garcia, Matt Hall, Zhezhen Jin, Lena E Winestone, Danielle Novetsky Friedman, Rachel Phelan, Christina Baggott, Samuel John, Holly L. Pacenta, Theodore W. Laetsch, Christine L Phillips, Michael R Verneris, Vanessa A. Fabrizio, Amy Keating, Julie-An Talano, Amy Moskop, Susanne H.C. Baumeister, Muna Qayed, Doug Douglas Myers, Erin Marie Hall, Snehit Prabhu, Khanh Nguyen, Casey A Carr, Crystal L. Mackall, John K Lin, Jeremy Goldhaber-Fiebert, Liora Michal Schultz
Journal: Blood
Blood (2023) 142 (Supplement 1): 6912.
https://doi.org/10.1182/blood-2023-187462
Published: 2023
Journal Articles

Risk Factors and Outcomes for Hematotoxicity Following Tisagenlecleucel for Pediatric B-Acute Lymphoblastic Leukemia

Free
Kevin O. McNerney, Vanessa A. Fabrizio, Aimee C. Talleur, Stephanie Si Lim, Alexandra Dreyzin, Christina Baggott, Anant Vatsayan, Jenna Rossoff, Snehit Prabhu, Holly L. Pacenta, Christine L Phillips, Julie-An Talano, Amy Moskop, Michael R Verneris, Douglas Myers, Nicole Karras, Challice L. Bonifant, Muna Qayed, Michelle L. Hermiston, Prakash Satwani, Christa Krupski, Amy Keating, Susanne H.C. Baumeister, Vasant Chinnabhandar, Emily Egeler, Kevin J Curran, Crystal L. Mackall, Theodore W. Laetsch, Liora Michal Schultz, Swati Naik
Journal: Blood
Blood (2023) 142 (Supplement 1): 2133.
https://doi.org/10.1182/blood-2023-189921
Published: 2023
Journal Articles

Transcriptional Profiling Associated with CD22 CAR T Cell Clinical Response in LBCL

Free
Anne Marijn Kramer, Mark P. Hamilton, Snehit Prabhu, Moksha Desai, Adam Kuo, Zachary Ehlinger, Neha Agarwal, Yi-Jiun Su, Nikolaos Gkitsas, Carley Fowler, Vimal Keerthi, Aidan Retherford, Dorota Klysz, Ramya Tunuguntla, Steven Feldman, Bita Sahaf, John H. Baird, Lori S. Muffly, Crystal L. Mackall, David B. Miklos, Zinaida Good, Matthew J. Frank
Journal: Blood
Blood (2023) 142 (Supplement 1): 2091.
https://doi.org/10.1182/blood-2023-187615
Published: 2023
Journal Articles

Peripheral Blast Count at Apheresis Acts Independent of Disease Burden As a Risk Factor for Survival Following Tisagenlecleucel in Children and Young Adults

Free
Vanessa A. Fabrizio, Kristen Miller, Christina Baggott, Snehit Prabhu, Holly Pacenta, Christine L. Phillips, Jenna Rossoff, Heather E. Stefanski, Julie Talano, Amy Moskop, Susanne H.C. Baumeister, Gary Douglas Myers, Nicole Karras, Patrick A. Brown, Muna Qayed, Michelle L. Hermiston, Prakash Satwani, Christa Krupski, Rachel Wilcox, Vasant Chinnabhandar, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, Amy K. Keating, Michael R. Verneris, Liora M. Schultz
Journal: Blood
Blood (2022) 140 (Supplement 1): 4661–4663.
https://doi.org/10.1182/blood-2022-169603
Published: 2022
Journal Articles

Obesity Associates with Inferior Outcomes and Toxicity in Pediatric and Young Adult Patient with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia Treated with Commercially Manufactured Tisagenlecleucel

Free
Anthony J Ross, Christina Baggott, Snehit Prabhu, Holly Pacenta, Christine Philips, Jenna Rossoff, Heather E Stefanski, Julie Talano, Amy Moskop, Susanne H.C. Baumeister, Michael R Verneris, Gary Douglas Myers, Nicole Karras, Muna Qayed, Michelle L. Hermiston, Prakash Satwani, Christa Krupski, Amy K. Keating, Rachel Wilcox, Vanessa A Fabrizio, Vasant Chinnabhandar, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, Sandra K Althouse, Shannon L. Maude, Curtis J Henry, Liora M. Schultz, Jodi L. Skiles
Journal: Blood
Blood (2022) 140 (Supplement 1): 10419–10421.
https://doi.org/10.1182/blood-2022-163336
Published: 2022
Journal Articles

Out-of-specification tisagenlecleucel does not compromise safety or efficacy in pediatric acute lymphoblastic leukemia

Free
Clinical Trials & Observations
Jenna Rossoff, Christina Baggott, Snehit Prabhu, Holly Pacenta, Christine L. Phillips, Heather Stefanski, Julie-An Talano, Amy Moskop, Steven P. Margossian, Michael R. Verneris, Gary Douglas Myers, Nicole Karras, Patrick A. Brown, Muna Qayed, Michelle Hermiston, Prakash Satwani, Christa Krupski, Amy K. Keating, Rachel Wilcox, Cara A. Rabik, Vanessa A. Fabrizio, Michael Kunicki, Vasant Chinnabhandar, A. Yasemin Goksenin, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, Liora M. Schultz
Journal: Blood
Blood (2021) 138 (21): 2138–2142.
https://doi.org/10.1182/blood.2021012392
Published: 2021
Journal Articles

Disease Burden Impacts Outcomes in Pediatric and Young Adult B-Cell Acute Lymphoblastic Leukemia after Commercial Tisagenlecleucel: Results from the Pediatric Real World CAR Consortium (PRWCC)

Free
Liora M. Schultz, MD, Christina Baggott, RN, PhD, Snehit Prabhu, PhD, Holly Pacenta, MD, Christine L Phillips, MD, Jenna Rossoff, MD, Heather Stefanski, MDPhD, Julie-An Talano, MD, Amy Moskop, MD, Steven P. Margossian, MD PhD, Michael R Verneris, MD, Gary Douglas Myers, MD, Nicole Karras, MD, Patrick A. Brown, MD, Muna Qayed, MDMSc, Michelle Hermiston, MD PhD, Prakash Satwani, MD, Christa Krupski, DO, MPH, Amy Keating, MD, Rachel Wilcox, Cara A Rabik, MDPhD, Vanessa Fabrizio, MD, Michael Kunicki, Vasant Chinnabhandar, MD, A. Yasemin Goksenin, MD PhD MA, MPH, Kevin J. Curran, MD, Crystal L. Mackall, MD, Theodore W. Laetsch, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 14–15.
https://doi.org/10.1182/blood-2020-134472
Published: 2020
Journal Articles

Real-World Treatment of Pediatric Patients with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia Using Tisagenlecleucel That Is out of Specification for Commercial Release

Free
Jenna Rossoff, MD, Christina Baggott, RN, PhD, Snehit Prabhu, PhD, Holly Pacenta, MD, Christine L Phillips, MD, Heather Stefanski, MDPhD, Julie-An Talano, MD, Amy Moskop, MD, Steven P. Margossian, MD PhD, Michael R Verneris, MD, Gary Douglas Myers, MD, Nicole Karras, MD, Patrick A. Brown, MD, Muna Qayed, MDMSc, Michelle Hermiston, MD PhD, Prakash Satwani, MD, Christa Krupski, DO, MPH, Amy Keating, MD, Rachel Wilcox, Cara A Rabik, MDPhD, Vanessa Fabrizio, MD, Michael Kunicki, Vasant Chinnabhandar, MD, A. Yasemin Goksenin, MD PhD MA, MPH, Kevin J. Curran, MD, Crystal L. Mackall, MD, Theodore W. Laetsch, MD, Liora M. Schultz, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42–44.
https://doi.org/10.1182/blood-2020-136674
Published: 2020