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Journal Articles

Machine learning uncovers invariant evolutionary molecular trajectories in MDS.

Matteo D'Addona, Arda Durmaz, Tariq Kewan, Waled Bahaj, Carlos Bravo-Perez, Luca Guarnera, Simona Pagliuca, Zachary Brady, Kartik Lakhotiya, Praveena Thiagarajan, Moaath Mustafa Ali, Abhay Singh, Hetty Carraway, Mark Orland, Carmelo Gurnari, Jacob Scott, Valeria Visconte, Jaroslaw Maciejewski

Blood (2025) 146 (Supplement 1): 2060.

https://doi.org/10.1182/blood-2025-2060

Published: 2025

Journal Articles

Which molecular patterns of high-risk myeloid malignancies are concordantly identified using two machine learning algorithms?

Tariq Kewan, Arda Durmaz, Waled Bahaj, Carmelo Gurnari, Olisaemeka Ogbue, Matteo D'Addona, Ahmad Kiwan, Hussein Awada, Simona Pagliuca, Hetty Carraway, Amer Zeidan, Suresh Kumar Balasubramanian, Taha Bat, Yazan Madanat, Valeria Visconte, Jaroslaw Maciejewski

Blood (2025) 146 (Supplement 1): 3485.

https://doi.org/10.1182/blood-2025-3485

Published: 2025

Journal Articles

An integrative prognostic model for transplant outcomes in myelofibrosis

Blood (2025) 146 (Supplement 1): 912.

https://doi.org/10.1182/blood-2025-912

Published: 2025

Journal Articles

Real-world use of oral iptacopan monotherapy in paroxysmal nocturnal hemoglobinuria

Blood (2025) 146 (Supplement 1): 1427.

https://doi.org/10.1182/blood-2025-1427

Published: 2025

Journal Articles

Dissecting complement pathway activation after allogeneic hematopoietic cell transplant: Results of a monocentric longitudinal monitoring program.

Camille Malbrun, Mélissa Julien, Antoine-Adrien Demasi, Emilie Darche, Gabrielle Roth-Guepin, Caroline Bonmati, Céline Kicki, Arnaud Campidelli, Anne Béatrice Notarantonio, Maud D'Aveni, Caroline Jacquet, Pierre Feugier, Christine André-Botté, Maxime Cravat, Tshinguta Mbuyi, Marcelo De Carvalho-Bittencourt, Marie-Thérèse Rubio, Simona Pagliuca

Blood (2025) 146 (Supplement 1): 6014.

https://doi.org/10.1182/blood-2025-6014

Published: 2025

Journal Articles

Survey on fertility management and outcomes after cellular therapies, on behalf of the EBMT cellular therapy and immunobiology working party

Blood (2025) 146 (Supplement 1): 130.

https://doi.org/10.1182/blood-2025-130

Published: 2025

Journal Articles

Celfib-AI: A machine learning model to predict bone marrow fibrosis and cellularity from complete blood count – a multicenter model development and validation study in France

Blood (2025) 146 (Supplement 1): 3801.

https://doi.org/10.1182/blood-2025-3801

Published: 2025

Journal Articles

Machine learning-derived, comprehensive “Geno-Immunome” of bone marrow failure syndromes reveals complex immunogenetic interactions with clinical implications

Aashray Mandala, Carlos Bravo-Perez, Mark Orland, Zachary Brady, Serhan Unlu, Atsushi Marumo, Kartik Lakhotiya, Christopher Haddad, Felipe de Almeida Sartori, Asfand Yar Cheema, Simona Pagliuca, Carmelo Gurnari, Valeria Visconte, Arda Durmaz, Jaroslaw Maciejewski

Blood (2025) 146 (Supplement 1): 2583.

https://doi.org/10.1182/blood-2025-2583

Published: 2025

Journal Articles

Hallmarks of allogeneic hematopoietic cell transplant success: A study on immune signatures and predictive features of graft versus host disease-free remission states from the SFGM-TC registry and cryostem biobank

Adrien Lapoutge, Mélanie Gaudfrin, Nicole Raus, Raynier Devillier, Anne Huynh, Arda Durmaz, Carmelo Gurnari, David Moulin, Natalia de Isla, Maud D'Aveni-Piney, Marie-Thérèse Rubio, Simona Pagliuca

Blood (2025) 146 (Supplement 1): 2476.

https://doi.org/10.1182/blood-2025-2476

Published: 2025

Journal Articles

Determining telomere content and genomics of myeloid neoplasia by whole-genome sequencing

Blood blood.2025028644.

https://doi.org/10.1182/blood.2025028644

Published: 2025

Includes: Supplemental data

Journal Articles

First Results of High Throughput Pipeline for Serotypic and TCR Clonotypic Specificities in Aplastic Anemia and Large Granular Lymphocyte Leukemia Uncovering Antigenic Peptides Relevant to Disease Etiology

Kartik Lakhotiya, Carmelo Gurnari, Carlos Bravo-Perez, Aashray Mandala, Matteo D'Addona, Christopher Haddad, Mark Orland, Zachary Brady, Luca Guarnera, Praveena Thiagarajan, Ishani Nautiyal, Simona Pagliuca, Hari Krishnamurthy, Karthik Krishna, Vasanth Jayaraman, Valeria Visconte, Jaroslaw Maciejewski, Arda Durmaz

Blood (2024) 144 (Supplement 1): 35.

https://doi.org/10.1182/blood-2024-210990

Published: 2024

Journal Articles

Unraveling Immunogenomic Features Germane to Pathobiology of Myelodysplastic Syndromes

Arda Durmaz, Zachary Brady, Kartik Lakhotiya, Benjamin Kroger, Hussein Awada, Yasuo Kubota, Jacky Chen, Colin Hercus, Sébastien Hergalant, Carlos Bravo-Perez, Maria Teresa Voso, Li Lily Wang, Jacob G. Scott, Hetty E. Carraway, Valeria Visconte, Stephen Chung, Simona Pagliuca, Jaroslaw Maciejewski, Carmelo Gurnari

Blood (2024) 144 (Supplement 1): 2224.

https://doi.org/10.1182/blood-2024-198530

Published: 2024

Journal Articles

Fludarabine and Treosulfan Conditioning Is Feasible and Leads to High OS and Low NRM

Chiara Bernardi, Stéphane Morisset, Amandine Pradier, Anne-Claire Mamez, Federica Giannotti, Sarah Morin, Stavroula Masouridi Levrat, Gabrielle Roth-Guepin, Maud D'Aveni, Céline Kicki, Arnaud Campidelli, Federico Simonetta, Simona Pagliuca, Yves Chalandon, Marie-Thérèse Rubio

Blood (2024) 144 (Supplement 1): 7301.

https://doi.org/10.1182/blood-2024-211435

Published: 2024

Journal Articles

Telomere Content Diversity in Myeloid Neoplasia Could Inform on Differential Sensitivity to Telomerase Inhibitors

Blood (2024) 144 (Supplement 1): 4104.

https://doi.org/10.1182/blood-2024-209923

Published: 2024

Journal Articles

An Immunogenetic Perspective on Bone Marrow Failure Syndromes: The KIR-HLA System

Aashray Mandala, Carlos Bravo-Perez, Matteo D'Addona, Zachary Brady, Mark Orland, Luca Guarnera, Kartik Lakhotiya, Christopher Haddad, Praveena Thiagarajan, Arooj Ahmed, Simona Pagliuca, Carmelo Gurnari, Valeria Visconte, Arda Durmaz, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 4084.

https://doi.org/10.1182/blood-2024-210304

Published: 2024

Journal Articles

Personalized Transplant Decision Making for Myelofibrosis in the Era of Molecular Genetics and JAK Inhibition

Nico Gagelmann, Barbara Mora, Filippo Branzanti, Alessandro Maria Vannucchi, Massimo Breccia, Giuseppe Alberto Maria Palumbo, Massimiliano Bonifacio, Erika Morsia, Elena Maria Elli, Mario Tiribelli, Giulia Benevolo, Mirko Farina, Fabrizio Pane, Roberto Massimo Lemoli, Giovanni Caocci, Alessia Tieghi, Gianni Binotto, Francesco Cavazzini, Bruno Martino, Alessandro Isidori, Margherita Maffioli, Elisa Rumi, Tiziano Barbui, Francisco Cervantes, Matteo Giovanni Della Porta, Andrew T. Kuykendall, Marianna Caramella, Alessandra Iurlo, Valerio De Stefano, Jean-Jacques Kiladjian, David Ross, Jason Gotlib, Timothy Devos, Marco Ruggeri, Richard T. Silver, Rachel B. Salit, Thomas Schroeder, Carmelo Gurnari, Simona Pagliuca, Christina Rautenberg, Marie Robin, Marie-Thérèse Rubio, Jaroslaw Maciejewski, Alessandro Rambaldi, Maria Chiara Finazzi, Andrea Bacigalupo, Patrizia Chiusolo, Hans Christian Reinhardt, Bart L. Scott, Nicolaus Kröger, Francesco Passamonti, Francesca Palandri

Blood (2024) 144 (Supplement 1): 245.

https://doi.org/10.1182/blood-2024-210804

Published: 2024

Journal Articles

Predictive Modeling of Hematopoietic Stem Cell Transplant Outcomes: Discovering the Role of Immunogenetic Features through Machine Learning Models

Simona Pagliuca, Carmelo Gurnari, Arda Durmaz, Ashwin Kishtagari, Zain Virk, Lukasz P. Gondek, Matthew Guo, Maria Bettinotti, Mark B Juckett, Qing Cao, Suresh Kumar Balasubramanian, Vikram Dhillon, Ben K. Tomlinson, Koen van Besien, Alice Aarnink, Marie Thérèse Rubio, Valeria Visconte, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 927.

https://doi.org/10.1182/blood-2024-210565

Published: 2024

Journal Articles

Paroxysmal nocturnal hemoglobinuria–related thrombosis in the era of novel therapies: a 2043-patient-year analysis

Carmelo Gurnari, Hussein Awada, Simona Pagliuca, Danai Dima, Fauzia Ullah, Naomi Kawashima, Yasuo Kubota, Ceylan Colak, Valeria Visconte, Bhumika J. Patel, Vikram Dhillon, Naimisha Marneni, Suresh Kumar Balasubramanian, Ashwin Kishtagari, Taha Bat, Jaroslaw P. Maciejewski

Blood (2024) 144 (2): 145–155.

https://doi.org/10.1182/blood.2024023988

Published: 2024

Journal Articles

Somatic and Germline HLA Determinants of Immune Surveillance and Escape in Myelodysplastic Syndromes

Carmelo Gurnari, Arda Durmaz, Benjamin Kroger, Hussein Awada, Jacky Chen, Colin Hercus, Sébastien Hergalant, Carlos Bravo-Perez, Maria Teresa Voso, Jacob Scott, Valeria Visconte, Stephen S. Chung, Jaroslaw P. Maciejewski, Simona Pagliuca

Blood (2023) 142 (Supplement 1): 3220.

https://doi.org/10.1182/blood-2023-178890

Published: 2023

Journal Articles

Interindividual HLA Evolutionary Divergence in Single HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation for Malignant Hematological Disorders: A Report on Behalf of the Cellular Therapy and Immunobiology Working Party of the EBMT

Blood (2023) 142 (Supplement 1): 895.

https://doi.org/10.1182/blood-2023-187622

Published: 2023

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Machine learning uncovers invariant evolutionary molecular trajectories in MDS.

Which molecular patterns of high-risk myeloid malignancies are concordantly identified using two machine learning algorithms?

An integrative prognostic model for transplant outcomes in myelofibrosis

Real-world use of oral iptacopan monotherapy in paroxysmal nocturnal hemoglobinuria

Dissecting complement pathway activation after allogeneic hematopoietic cell transplant: Results of a monocentric longitudinal monitoring program.

Survey on fertility management and outcomes after cellular therapies, on behalf of the EBMT cellular therapy and immunobiology working party

Celfib-AI: A machine learning model to predict bone marrow fibrosis and cellularity from complete blood count – a multicenter model development and validation study in France

Machine learning-derived, comprehensive “Geno-Immunome” of bone marrow failure syndromes reveals complex immunogenetic interactions with clinical implications

Hallmarks of allogeneic hematopoietic cell transplant success: A study on immune signatures and predictive features of graft versus host disease-free remission states from the SFGM-TC registry and cryostem biobank

Determining telomere content and genomics of myeloid neoplasia by whole-genome sequencing

First Results of High Throughput Pipeline for Serotypic and TCR Clonotypic Specificities in Aplastic Anemia and Large Granular Lymphocyte Leukemia Uncovering Antigenic Peptides Relevant to Disease Etiology

Unraveling Immunogenomic Features Germane to Pathobiology of Myelodysplastic Syndromes

Fludarabine and Treosulfan Conditioning Is Feasible and Leads to High OS and Low NRM

Telomere Content Diversity in Myeloid Neoplasia Could Inform on Differential Sensitivity to Telomerase Inhibitors

An Immunogenetic Perspective on Bone Marrow Failure Syndromes: The KIR-HLA System

Personalized Transplant Decision Making for Myelofibrosis in the Era of Molecular Genetics and JAK Inhibition

Predictive Modeling of Hematopoietic Stem Cell Transplant Outcomes: Discovering the Role of Immunogenetic Features through Machine Learning Models

Paroxysmal nocturnal hemoglobinuria–related thrombosis in the era of novel therapies: a 2043-patient-year analysis

Somatic and Germline HLA Determinants of Immune Surveillance and Escape in Myelodysplastic Syndromes

Interindividual HLA Evolutionary Divergence in Single HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation for Malignant Hematological Disorders: A Report on Behalf of the Cellular Therapy and Immunobiology Working Party of the EBMT

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American Society of Hematology

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