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Journal Articles

Rapidly progressive acute chest syndrome is associated with complement-mediated cell injury in adults with sickle cell disease

Jose Mejias Figueroa, Shruti Chaturvedi, Michael DeBaun, Gloria Gerber, Robert Brodsky, Michael Cole, Daniel Flores-Guerrero, Xuan Yuan

Blood (2025) 146 (Supplement 1): 6485.

https://doi.org/10.1182/blood-2025-6485

Published: 2025

Journal Articles

Danicopan add-on therapy demonstrates positive efficacy and safety outcomes in advanced age adults with paroxysmal nocturnal hemoglobinuria and clinically significant extravascular hemolysis: A sub-analysis of the phase 3 ALPHA trial

Austin Kulasekararaj, Morag Griffin, Robert Brodsky, Jun-ichi Nishimura, Christopher Patriquin, Hubert Schrezenmeier, Wilma Barcellini, Anna Gaya, Yogesh Patel, Ying Tang, Gleb Filippov, Mohammed Mahdi, Flore Sicre-de-Fontbrune, Jong Wook Lee

Blood (2025) 146 (Supplement 1): 949.

https://doi.org/10.1182/blood-2025-949

Published: 2025

Journal Articles

Enhanced procoagulant activity of phosphatidylserine-positive platelets in antiphospholipid syndrome

Charles Sukin, Paresh Kulkarni, Anne Hubben, Bhagwati Joshi, Michael Cole, Dana Angelini, Sandra Mazzoni, Robert Brodsky, Keith McCrae

Blood (2025) 146 (Supplement 1): 1249.

https://doi.org/10.1182/blood-2025-1249

Published: 2025

Journal Articles

Analysis of healthcare utilization costs prior to and after non-myeloablative haploidentical allogeneic stem cell transplantation in adults with sickle cell disease

Ijele Adimora, Bethel Abraham, Robert Brodsky, Richard Jones, Javier Bolanos-Meade, Jeromie Ballreich

Blood (2025) 146 (Supplement 1): 2599.

https://doi.org/10.1182/blood-2025-2599

Published: 2025

Journal Articles

NLRP3 inflammasome inhibition fails to prevent red blood cell lysis in PNH

Nikhil Ranjan, Michael Cole, Gloria Gerber, Daniel Flores-Guerrero, Shruti Chaturvedi, Robert Brodsky

Blood (2025) 146 (Supplement 1): 2895.

https://doi.org/10.1182/blood-2025-2895

Published: 2025

Journal Articles

Complement-induced procoagulant platelets in patients with antiphospholipid antibodies

Paresh Kulkarni, Maierdan Palihati, Anne Hubben, Michael Cole, Bhagwati Joshi, Dana Angelini, Sandra Mazzoni, Shruti Chaturvedi, Robert Brodsky, Keith McCrae

Blood (2025) 146 (Supplement 1): 416.

https://doi.org/10.1182/blood-2025-416

Published: 2025

Journal Articles

Reduced intensity haploidentical bone marrow transplantation in children with severe sickle cell disease (SCD): BMT CTN 1507

Blood (2025) 146 (Supplement 1): 164.

https://doi.org/10.1182/blood-2025-164

Published: 2025

Journal Articles

High rates of hypertension, improved renal outcomes in complement-mediated thrombotic microangiopathy

Charlotte Story, Robert Brodsky, Shruti Chaturvedi

Blood (2025) 146 (Supplement 1): 4884.

https://doi.org/10.1182/blood-2025-4884

Published: 2025

Journal Articles

Silent Cerebral Infarction during Immune TTP Remission - Prevalence, Predictors and Impact on Cognition

Jia Yu, Jenna Brown, Eli Salzberg, Aria Wei, Gloria Gerber, Xiang-Zuo Pan, Alison R. Moliterno, MIchael B. Streiff, Peggy Kraus, Claire Logue, Jennifer Yui, Rakhi P.P. Naik, Hira Latif, Sophie M. Lanzkron, Evan M. Braunstein, Robert Brodsky, Michael R. DeBaun, Doris Lin, Shruti Chaturvedi

Blood (2022) 140 (Supplement 1): 338–340.

https://doi.org/10.1182/blood-2022-167054

Published: 2022

Journal Articles

Prospective Study of Complement Activation with Functional and Genetic Assays in Sickle Cell Disease

Christos Varelas, Efthymia Vlachaki, Filippos Klonizakis, Despoina Pantelidou, Fani Minti, Michael D. Diamantidis, Nikolaos Sampanis, Ioanna Giatagantzidou, Despoina Papadopoulou, Evdoxia Koravou, Ioanna Christodoulou, Evaggelia Zarkada, Tasoula Touloumenidou, Apostolia Papalexandri, Ioanna Sakellari, George Vassilopoulos, Robert Brodsky, Eleni Gavriilaki

Blood (2022) 140 (Supplement 1): 2504–2505.

https://doi.org/10.1182/blood-2022-164554

Published: 2022

Journal Articles

Alternative Bone Marrow Transplantation with Post-Transplant Cyclophosphamide (PTCy) As Initial Therapy for Acquired Severe Aplastic Anemia (SAA)

Amy E. DeZern, Marianna Zahurak, Kenneth R. Cooke, Richard J. Jones, Robert Brodsky

Blood (2022) 140 (Supplement 1): 4868–4869.

https://doi.org/10.1182/blood-2022-157861

Published: 2022

Journal Articles

Pathogenicity of Sars-Cov-2 Spike Protein Variants Correlates with Coagulation and Complement Assays

Gloria Gerber, Xiang-Zuo Pan, Nikhil Ranjan, Anna Warmack, Robert Brodsky

Blood (2022) 140 (Supplement 1): 2705–2706.

https://doi.org/10.1182/blood-2022-169738

Published: 2022

Journal Articles

Silent Cerebral Infarction on Brain MRI Is Associated with Cognitive Impairment in Ittp Survivors in Hematological Remission

Jia Yu, Aria Wei, Xiang-Zuo Pan, Gloria Frances Gerber, Sarah Hussain, Alison R. Moliterno, Michael B. Streiff, Peggy Kraus, Claire Logue, Jennifer Yui, Rakhi P. Naik, Hira Latif, Ruhail Kohli, Sophie M. Lanzkron, Evan M. Braunstein, Robert Brodsky, Doris Lin, Shruti Chaturvedi

Blood (2021) 138 (Supplement 1): 774.

https://doi.org/10.1182/blood-2021-151304

Published: 2021

Journal Articles

Abundance of B Cell Receptors Harboring Elongated Polytyrosine and Polyserine Rich Motifs within Their Heavy Chain CDR3 Distinguishes Catastrophic and Antiphospholipid Syndrome

Shadi Swaidani, Shruti Chaturvedi, Xiang-Zuo Pan, Robert Brodsky, Renren Wen, Alok A Khorana, Keith R. McCrae

Blood (2021) 138 (Supplement 1): 2117.

https://doi.org/10.1182/blood-2021-148158

Published: 2021

Journal Articles

Prevalence and Characteristics of Venous Thromboembolism in Patients with Complement Mediated Thrombotic Microangiopathy

Aria Wei, Gloria Frances Gerber, Kathryn Dane, Evan M. Braunstein, Robert Brodsky, Shruti Chaturvedi

Blood (2021) 138 (Supplement 1): 2091.

https://doi.org/10.1182/blood-2021-152904

Published: 2021

Journal Articles

Outcomes of Non-Myeloablative HLA-Haploidentical Bone Marrow Transplant with Thiotepa and Post-Transplant Cyclophosphamide in Children and Adults with Severe Sickle Cell Disease, a Phase II Trial: Vanderbilt Global Haploidentical Transplant Learning Collaborative (VGC 2 )

Adetola A. Kassim, MDMS, Josu de la Fuente, Ali Debsan Alahmari, MBBS, MD MNAMS, Michael J. Eckrich, MD MPH, Rabi Hanna, MD, Nathalie Dhedin, MD, Biljana N. Horn, MD, Vandy Black, MDMSc, Roseane V Gouveia, Adriana Seber, MDMS, Belinda Pinto Simões, MD PhD, Thalita Cristina de Mello Costa, MD, Renato Guerino-Cunha, Carmem M. S. Bonfim, MDPhD, Roberto Luiz da Silva, Nelson Hamerschlak, MD PhD, Juliana Folloni Fernandes, MD, Michael Kent, MDBS, Satya Prakash Yadav, MBBS, MD, Erfan Nur, MDPhD, Mohsen Alzahrani, Ben Carpenter, PhD, William Tse, MD, Maria Isabel, Hemalatha G Rangarajan, MD, Ibrahim Ahmed, MD, Adeseye Michael Akinsete, MBBS, Courtney D. Fitzhugh, MD, Kathryn A. Culos, PharmD, Leena Karnik, FRCPath, MRCP, James Connelly, MD, Carrie Kitko, MD, Jennifer Andrews, MDMSc, Karina L Wilkerson, NP, MSN, Robert Brodsky, Tatsuki Koyama, Michael R. DeBaun, MD MPH

Blood (2020) 136 (Supplement 1): 8–9.

https://doi.org/10.1182/blood-2020-141771

Published: 2020

Journal Articles

Defects in Sialic Acid Biosynthesis Cause Dysregulation of the Alternative Pathway of Complement

Hang Chen, Luyi Peng, Jia Yu, BS, Xuan Yuan, MD MSc, Shruti Chaturvedi, MBBS,MS, Robert Brodsky, MD, Evan M Braunstein, MDPhD

Blood (2020) 136 (Supplement 1): 3.

https://doi.org/10.1182/blood-2020-141289

Published: 2020

Journal Articles

Outcomes of a Clinician-Directed Protocol for Discontinuation of Complement Inhibition Therapy in Atypical Hemolytic Uremic Syndrome

Noor Dhaliwal, Sarah Hussain, Harshvardhan Upreti, Evan M Braunstein, MDPhD, Xuan Yuan, MD MSc, Alison R. Moliterno, MD, Robert Brodsky, MD, Shruti Chaturvedi, MBBS,MS

Blood (2020) 136 (Supplement 1): 24–25.

https://doi.org/10.1182/blood-2020-142965

Published: 2020

Journal Articles

Phase 3 Study of Danicopan, an Oral Complement Factor D Inhibitor, As Add-on Therapy to a C5 Inhibitor in Patients with Paroxysmal Nocturnal Hemoglobinuria with Clinically Evident Extravascular Hemolysis

Austin Kulasekararaj, MDMBBS,MRCP,FRCPath, Antonio Risitano, Jong Wook Lee, MD, PhD, Mingjun Huang, PhD, Jun-Ichi Nishimura, MD PhD, Alejandra Ramirez-Santiago, Robert Brodsky

Blood (2020) 136 (Supplement 1): 6–7.

https://doi.org/10.1182/blood-2020-134388

Published: 2020

Journal Articles

Single-board hematology fellowship track: a 10-year institutional experience

Rakhi P. Naik, Kristen Marrone, Samuel Merrill, Ross Donehower, Robert Brodsky

Blood (2018) 131 (4): 462–464.

https://doi.org/10.1182/blood-2017-11-816207

Published: 2018

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Rapidly progressive acute chest syndrome is associated with complement-mediated cell injury in adults with sickle cell disease

Danicopan add-on therapy demonstrates positive efficacy and safety outcomes in advanced age adults with paroxysmal nocturnal hemoglobinuria and clinically significant extravascular hemolysis: A sub-analysis of the phase 3 ALPHA trial

Enhanced procoagulant activity of phosphatidylserine-positive platelets in antiphospholipid syndrome

Analysis of healthcare utilization costs prior to and after non-myeloablative haploidentical allogeneic stem cell transplantation in adults with sickle cell disease

NLRP3 inflammasome inhibition fails to prevent red blood cell lysis in PNH

Complement-induced procoagulant platelets in patients with antiphospholipid antibodies

Reduced intensity haploidentical bone marrow transplantation in children with severe sickle cell disease (SCD): BMT CTN 1507

High rates of hypertension, improved renal outcomes in complement-mediated thrombotic microangiopathy

Silent Cerebral Infarction during Immune TTP Remission - Prevalence, Predictors and Impact on Cognition

Prospective Study of Complement Activation with Functional and Genetic Assays in Sickle Cell Disease

Alternative Bone Marrow Transplantation with Post-Transplant Cyclophosphamide (PTCy) As Initial Therapy for Acquired Severe Aplastic Anemia (SAA)

Pathogenicity of Sars-Cov-2 Spike Protein Variants Correlates with Coagulation and Complement Assays

Silent Cerebral Infarction on Brain MRI Is Associated with Cognitive Impairment in Ittp Survivors in Hematological Remission

Abundance of B Cell Receptors Harboring Elongated Polytyrosine and Polyserine Rich Motifs within Their Heavy Chain CDR3 Distinguishes Catastrophic and Antiphospholipid Syndrome

Prevalence and Characteristics of Venous Thromboembolism in Patients with Complement Mediated Thrombotic Microangiopathy

Outcomes of Non-Myeloablative HLA-Haploidentical Bone Marrow Transplant with Thiotepa and Post-Transplant Cyclophosphamide in Children and Adults with Severe Sickle Cell Disease, a Phase II Trial: Vanderbilt Global Haploidentical Transplant Learning Collaborative (VGC 2 )

Defects in Sialic Acid Biosynthesis Cause Dysregulation of the Alternative Pathway of Complement

Outcomes of a Clinician-Directed Protocol for Discontinuation of Complement Inhibition Therapy in Atypical Hemolytic Uremic Syndrome

Phase 3 Study of Danicopan, an Oral Complement Factor D Inhibitor, As Add-on Therapy to a C5 Inhibitor in Patients with Paroxysmal Nocturnal Hemoglobinuria with Clinically Evident Extravascular Hemolysis

Single-board hematology fellowship track: a 10-year institutional experience

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