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Journal Articles

PHF19 inhibition increases IMiDs sensitivity by epigenetically regulating IRF4 and MYC in multiple myeloma

Xiyue Sun, Tengteng Yu, Teng Fang, Hao Sun, Xiaoyu Zhang, Zhen Yu, Lanting Liu, Gang An, Lugui Qiu, Mu Hao

Blood (2025) 146 (Supplement 1): 2164.

https://doi.org/10.1182/blood-2025-2164

Published: 2025

Journal Articles

Prognostic significance of clinical risk models and genomic alterations in Waldenström macroglobulinemia before or after BTK inhibitor era

Weihao Chen, Yuting Yan, Ying Yu, Yuxi Li, Xiong Wenjie, Xinyi Zhang, Tingyu Wang, Wei LIU, Weiwei Sui, Zhen Yu, Mu Hao, Gang An, Dehui Zou, Lugui Qiu, Shuhua Yi

Blood (2025) 146 (Supplement 1): 3593.

https://doi.org/10.1182/blood-2025-3593

Published: 2025

Journal Articles

LILRB4 drives proinflammatory cytokine secretion in multiple myeloma to promote the immune-cell dysfunction via the generation of myeloid-derived suppressive cells

Lanting Liu, Hao Sun, Yijie Wang, Xiyue Sun, Gang An, Lugui Qiu, Mu Hao

Blood (2025) 146 (Supplement 1): 5695.

https://doi.org/10.1182/blood-2025-5695

Published: 2025

Journal Articles

Novel indirubin-3-monoxime derivative I3MV-8b enhances anti-CD38 monoclonal antibody efficacy in multiple myeloma through dual proteasome and HDAC6 inhibition

Xiaoyu Zhang, Xiyue Sun, Yijie Wang, Lanting Liu, Zhen Yu, Mu Hao, Lugui Qiu

Blood (2025) 146 (Supplement 1): 5708.

https://doi.org/10.1182/blood-2025-5708

Published: 2025

Journal Articles

PSMD3 orchestrates metabolic reprogramming and immunogenic cell death in multiple myeloma

Teng Fang, Ting Du, Arghya Ray, Xueping Wan, Minxing Wang, Sindhu Pillai, Md Abu Musa, Filip Garbicz, Kenneth Wen, Mu Hao, Lugui Qiu, Yan Song, Kenneth Anderson

Blood (2025) 146 (Supplement 1): 3926.

https://doi.org/10.1182/blood-2025-3926

Published: 2025

Journal Articles

Determination of MYD88 and CXCR4 Mutation for Clinical Detection and Their Significance in Waldenström Macroglobulinemia

Blood (2024) 144 (Supplement 1): 4349.

https://doi.org/10.1182/blood-2024-202324

Published: 2024

Journal Articles

TRIM28 Serves As a Key Regulator of Protein Homeostasis and Mediates Proteasome Inhibitor Resistance in Multiple Myeloma

Teng Fang, Lanting Liu, Hao Sun, Xiyue Sun, Zhen Yu, Lugui Qiu, Mu Hao

Blood (2024) 144 (Supplement 1): 4668.

https://doi.org/10.1182/blood-2024-204159

Published: 2024

Journal Articles

Clinical Implications of Residual Immunophenotypically Normal Plasma Cells within Bone Marrow at Various Disease Stages in Multiple Myeloma

Wenqiang Yan, Lihui Shi, Jingyu Xu, Lingna Li, Jian Cui, Chenxing DU, Tengteng Yu, Shuaishuai Zhang, Rui Lv, Weiwei Sui, Shuhui Deng, Yan Xu, Dehui Zou, Lu-Gui Qiu, Mu Hao, Gang An

Blood (2024) 144 (Supplement 1): 1932.

https://doi.org/10.1182/blood-2024-199452

Published: 2024

Journal Articles

26S Proteasome Non-Atpase Subunit 3 (PSMD3/Rpn3) Is a Potential Therapeutic Target in Multiple Myeloma

Teng Fang, Yan Song, Ting Du, Arghya Ray, Xueping Wan, Minxing Wang, Sindhu C Pillai, Md. Abu Musa, Mu Hao, Lugui Qiu, Dharminder Chauhan, Kenneth C. Anderson

Blood (2024) 144 (Supplement 1): 1905.

https://doi.org/10.1182/blood-2024-206000

Published: 2024

Journal Articles

A Novel Indirubin-3-Monoxime Derivative Enhance Immune Cell Mediated Cytotoxicity in Multiple Myeloma

Xiaoyu Zhang, Xiyue Sun, Lanting Liu, Zhen Yu, Lu-Gui Qiu, Mu Hao

Blood (2024) 144 (Supplement 1): 7467.

https://doi.org/10.1182/blood-2024-202892

Published: 2024

Journal Articles

Single-Cell RNA Analysis of Bone Marrow Mononuclear Cells Reveals Abnormal Activation of T Cells and Monocytes, and Identifies CD35 As a Novel Biomarker and Therapeutic Target in Waldenstrom Macroglobulinemia

Hao Sun, Xia Liu, Maria Luisa Guerrera, Nickolas Tsakmaklis, Amanda Kofides, Andres Felipe Ramirez Gamero, Catherine A. Flynn, Christopher J Patterson, Mu Hao, Lugui Qiu, Shayna R Sarosiek, Jorge J. Castillo, Zachary R Hunter, Shirong Liu, Steven P. Treon

Blood (2024) 144 (Supplement 1): 743.

https://doi.org/10.1182/blood-2024-211488

Published: 2024

Journal Articles

Critical Roles of LILRB4 in Promoting PIM Kinase Mediated Cell Proliferation and Tumorigenesis in Multiple Myeloma

Yijie Wang, Jingyuan Ma, Xiyue Sun, Lixin Gong, Lanting Liu, Gang An, Lu-Gui Qiu, Mu Hao

Blood (2024) 144 (Supplement 1): 3262.

https://doi.org/10.1182/blood-2024-202920

Published: 2024

Journal Articles

Genomic Evolution By Serial Single-Cell Sequencing Identifies High Tumor Expression of LYN As a Promoter of Resistance in Waldenstrom's Macroglobulinemia Undergoing Ibrutinib Monotherapy

Hao Sun, Romanos Sklavenitis-Pistofidis, Xia Liu, Nickolas Tsakmaklis, Maria Luisa Guerrera, Amanda Kofides, Andres Felipe Ramirez Gamero, Catherine A. Flynn, Christopher J Patterson, Mu Hao, Lu-Gui Qiu, Shayna R Sarosiek, Jorge J. Castillo, Zachary R Hunter, Shirong Liu, Steven P. Treon

Blood (2024) 144 (Supplement 1): 4338.

https://doi.org/10.1182/blood-2024-211597

Published: 2024

Journal Articles

Single-Cell Multi-Omics Analysis Reveals Heterogeneity of Malignant Plasma Cell during Progression of Multiple Myeloma

Fangshuo Feng, Hao Sun, Xiaoyu Zhang, Xiyue Sun, Tengteng Yu, Haiqing Xiong, Gang An, Lu-Gui Qiu, Mu Hao

Blood (2024) 144 (Supplement 1): 6845.

https://doi.org/10.1182/blood-2024-203100

Published: 2024

Journal Articles

TENT5C As a Target of Chromatin Remodeler SMARCA2 Participates BTK Inhibitor Resistance in Mantle Cell Lymphoma By Regulating ATP Metabolism

Yuting Yan, Dandan Shan, Ying Yu, Weihao Chen, Xinyi Zhang, Xiong Wenjie, Tingyu Wang, Mu Hao, Gang An, Lu-Gui Qiu, Zhen Yu, Shuhua Yi

Blood (2024) 144 (Supplement 1): 832.

https://doi.org/10.1182/blood-2024-201941

Published: 2024

Journal Articles

Synergistic Induction of Senescence-Driven Immune Responses and Myeloma Cell Cytotoxicity By CDK4/6 Inhibitors and Daratumumab Combination Therapy

Shiyi Xie, Zhen Yu, Mu Hao, Lu-Gui Qiu, Mariateresa Fulciniti, Nikhil C. Munshi, Yan Xu

Blood (2024) 144 (Supplement 1): 1410.

https://doi.org/10.1182/blood-2024-200479

Published: 2024

Journal Articles

CRIP1 Involves the Pathogenesis of Multiple Myeloma Via Dual-Regulation of Proteasome and Autophagy

Zhen Yu, Peixia Tang, Zhenshu Xu, Lugui Qiu, Mu Hao

Blood (2023) 142 (Supplement 1): 6598.

https://doi.org/10.1182/blood-2023-179724

Published: 2023

Journal Articles

A Novel Indirubin-3-Monoxime Derivative Functions As Regulator of Proteostasis Via Targeting TRIM28 in Multiple Myeloma

Teng Fang, Hao Sun, Xiyue Sun, Zhen Yu, Xiaoyu Zhang, Lanting Liu, Lixin Gong, Shiyi Xie, Mu Hao, Lugui Qiu

Blood (2023) 142 (Supplement 1): 6572.

https://doi.org/10.1182/blood-2023-180712

Published: 2023

Journal Articles

High Level of IL-16 Secreted By Non-GCB DLBCL Facilitates Tumor Growth Though the Tumor-Promoting and Immunosuppressive Tumor Microenvironment

Xuwen Guan, Teng Fang, Yi Wang, Wei Liu, Mu Hao, Lugui Qiu

Blood (2023) 142 (Supplement 1): 6080.

https://doi.org/10.1182/blood-2023-180840

Published: 2023

Journal Articles

Enhanced Expression of DNp73 Promotes Drug Resistance and Immune Evasion in Multiple Myeloma By Targeting the MYC and MYCN Pathways

Lanting Liu, Lugui Qiu, Zhen Yu, Mu Hao

Blood (2023) 142 (Supplement 1): 4661.

https://doi.org/10.1182/blood-2023-177606

Published: 2023

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PHF19 inhibition increases IMiDs sensitivity by epigenetically regulating IRF4 and MYC in multiple myeloma

Prognostic significance of clinical risk models and genomic alterations in Waldenström macroglobulinemia before or after BTK inhibitor era

LILRB4 drives proinflammatory cytokine secretion in multiple myeloma to promote the immune-cell dysfunction via the generation of myeloid-derived suppressive cells

Novel indirubin-3-monoxime derivative I3MV-8b enhances anti-CD38 monoclonal antibody efficacy in multiple myeloma through dual proteasome and HDAC6 inhibition

PSMD3 orchestrates metabolic reprogramming and immunogenic cell death in multiple myeloma

Determination of MYD88 and CXCR4 Mutation for Clinical Detection and Their Significance in Waldenström Macroglobulinemia

TRIM28 Serves As a Key Regulator of Protein Homeostasis and Mediates Proteasome Inhibitor Resistance in Multiple Myeloma

Clinical Implications of Residual Immunophenotypically Normal Plasma Cells within Bone Marrow at Various Disease Stages in Multiple Myeloma

26S Proteasome Non-Atpase Subunit 3 (PSMD3/Rpn3) Is a Potential Therapeutic Target in Multiple Myeloma

A Novel Indirubin-3-Monoxime Derivative Enhance Immune Cell Mediated Cytotoxicity in Multiple Myeloma

Single-Cell RNA Analysis of Bone Marrow Mononuclear Cells Reveals Abnormal Activation of T Cells and Monocytes, and Identifies CD35 As a Novel Biomarker and Therapeutic Target in Waldenstrom Macroglobulinemia

Critical Roles of LILRB4 in Promoting PIM Kinase Mediated Cell Proliferation and Tumorigenesis in Multiple Myeloma

Genomic Evolution By Serial Single-Cell Sequencing Identifies High Tumor Expression of LYN As a Promoter of Resistance in Waldenstrom's Macroglobulinemia Undergoing Ibrutinib Monotherapy

Single-Cell Multi-Omics Analysis Reveals Heterogeneity of Malignant Plasma Cell during Progression of Multiple Myeloma

TENT5C As a Target of Chromatin Remodeler SMARCA2 Participates BTK Inhibitor Resistance in Mantle Cell Lymphoma By Regulating ATP Metabolism

Synergistic Induction of Senescence-Driven Immune Responses and Myeloma Cell Cytotoxicity By CDK4/6 Inhibitors and Daratumumab Combination Therapy

CRIP1 Involves the Pathogenesis of Multiple Myeloma Via Dual-Regulation of Proteasome and Autophagy

A Novel Indirubin-3-Monoxime Derivative Functions As Regulator of Proteostasis Via Targeting TRIM28 in Multiple Myeloma

High Level of IL-16 Secreted By Non-GCB DLBCL Facilitates Tumor Growth Though the Tumor-Promoting and Immunosuppressive Tumor Microenvironment

Enhanced Expression of DNp73 Promotes Drug Resistance and Immune Evasion in Multiple Myeloma By Targeting the MYC and MYCN Pathways

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