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Mitchell Horwitz
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Journal Articles

Upstream integration of implementation planning in clinical trials through the blood and marrow transplant clinical trials network

Free
Anna Desalvo, Brittany Ragon, Neel Bhatt, Betty K. Hamilton, Azra Borogovac, Mary Horowitz, Nandita Khera, Mark Juckett, Steven Devine, Christopher Dandoy, Alla Keyzner, Yvonne Efebera, John Plastaras, Mitchell Horwitz, Sarah Wall, Valerie Stewart, Mykala Heuer, Todd Molfenter
Journal: Blood
Blood (2025) 146 (Supplement 1): 7913.
https://doi.org/10.1182/blood-2025-7913
Published: 2025
Journal Articles

Remote multi-vital sign monitoring allows earlier detection of cytokine release syndrome after bispecific T cell engager and chimeric antigen receptor T cell therapies

Free
Chenyu Lin, Melinda Chen, Jingchen Chai, Janvi Jani, Sashi Kolli, Daniel Schrum, Erin Eberwein, Catie Cash, Jen Tichon, Amy Bush, Lauren Hill, Joey Misuraca, Matthew McKinney, Gwynn Long, Cristina Gasparetto, Taewoong Choi, Sendhilnathan Ramalingam, Suzanne Kirby, Thomas LeBlanc, Andrea Sitlinger, Anthony Sung, Raul Torres, Kellie Rutledge, Matthew Ream, John Gannon, Yubin Kang, Stefanie Sarantopoulos, Mitchell Horwitz, Jenifer Siegelman, Ruth Phillips, Sin-Ho Jung, Erik Koenig
Journal: Blood
Blood (2025) 146 (Supplement 1): 1075.
https://doi.org/10.1182/blood-2025-1075
Published: 2025
Journal Articles

Phase I trial of ruxolitinib plus fostamatinib for the treatment of steroid refractory chronic graft versus host disease

Free
Chenyu Lin, Zhiguo Li, Kouros Owzar, Alexander Sibley, Wei Jia, Ivan Spasojevic, Nelson Chao, Richard Lopez, Gwynn Long, Sanghee Hong, Amy Bush, Jen Tichon, Lauren Hill, Mitchell Horwitz, Stefanie Sarantopoulos
Journal: Blood
Blood (2025) 146 (Supplement 1): 2479.
https://doi.org/10.1182/blood-2025-2479
Published: 2025
Journal Articles

Understanding Sociodemographic Barriers in Hematopoietic Stem Cell Transplantation Among Patients with Hematologic Malignancies: Insights from a North Carolina Cohort

Free
Marie Michele Sainvil, Melissa Lowe, Delaney Underwood, Yan Li, Tomi F. Akinyemiju, Taewoong Choi, Cristina Gasparetto, Mitchell Horwitz, Gwynn D. Long, Richard Lopez, Stefanie Sarantopoulos, Edwin Alyea, III, Nelson J. Chao, Thomas W. LeBlanc, Yubin Kang, Sendhilnathan Ramalingam, Anthony D. Sung, Sanghee Hong
Journal: Blood
Blood (2024) 144 (Supplement 1): 2295.
https://doi.org/10.1182/blood-2024-211219
Published: 2024
Journal Articles

Long Term Outcomes of a Randomized Trial of Anti-T Lymphocyte Globulin to Improve Moderate-Severe Chronic Gvhd Free Survival after Unrelated Donor Hematopoietic Cell Transplantation: A CIBMTR Analysis

Free
Robert J. Soiffer, Mitchell Horwitz, Joseph P. McGuirk, Sudhindra Rao, Peter Westervelt, John F. DiPersio, Laura Johnston, Jonathan Serody, Witold B Rybka, Paul Shaughnessy, Joseph A. Pidala, Vincent Ho, Andrew Artz, Madhuri Vusirikala, David L. Porter, Paul J. Martin, David Avigan, Michael R Bishop, Ran Reshef, Andrew Peterson, Kwang Wooahn, Adetola A. Kassim, Ryotaro Nakamura, Yi-Bin Chen, Linda Burns
Journal: Blood
Blood (2024) 144 (Supplement 1): 4911.
https://doi.org/10.1182/blood-2024-205572
Published: 2024
Journal Articles

Interim Results from a Phase 2 Pivotal Study (DALY II USA) of Tandem CD20-CD19-Directed Non-Cryopreserved CAR-T Cells - Zamtocabtagene Autoleucel (Zamto-Cel) in Patients with Relapsed/Refractory Diffuse Large B Cell Lymphoma

Free
Nirav N. Shah, Richard T. Maziarz, Caron A. Jacobson, Patrick B. Johnston, Sunil Abhyankar, Iris Isufi, Miguel Angel Perales, Monalisa Ghosh, Matthew Ulrickson, Allison C. Rosenthal, Javier L. Munoz, Nancy M. Hardy, Aaron P. Rapoport, Reem Karmali, Farrukh T. Awan, Matthew Stuart McKinney, Mitchell Horwitz, Matthew Lunning, Nathan Denlinger, Marek Ancukiewicz, Madhavi Nallewar, Kimberly C Coleman, Esther Eromosele, Remigiusz Kaleta, Johanna Theruvath, Anna Wijatyk, David B. Miklos
Journal: Blood
Blood (2024) 144 (Supplement 1): 68.
https://doi.org/10.1182/blood-2024-208539
Published: 2024
Journal Articles

Disparities in CAR-T Therapy Access and Outcomes: Variation in Referral Patterns for CAR-T Therapy in Patients with Newly Diagnosed Malignancies at an Academic Center in North Carolina

Free
Marie Michele Sainvil, Melissa Lowe, Delaney Underwood, Yan Li, Tomi F. Akinyemiju, Taewoong Choi, Cristina Gasparetto, Mitchell Horwitz, Gwynn D. Long, Richard Lopez, Stefanie Sarantopoulos, Edwin Alyea, III, Nelson J. Chao, Thomas W. LeBlanc, Yubin Kang, Suzanne Kirby, Chenyu Lin, Matthew Stuart McKinney, Alexandra Stefanovic, Jie Wang, Andrea Sitlinger, Sendhilnathan Ramalingam, Anthony D. Sung, Sanghee Hong
Journal: Blood
Blood (2024) 144 (Supplement 1): 5044.
https://doi.org/10.1182/blood-2024-211637
Published: 2024
Journal Articles

Omidubicel-Onlv for Allogeneic Transplantation (allo-HCT) in Patients with Hematologic Malignancies: Results of a Multicenter Open Label Expanded Access Program

Free
Mitchell Horwitz, Stephanie B. Tsai, Andrew R. Rezvani, Richard T Maziarz, Uri Goshen, Stuart Levy, Aurelie Schwarzbach, Roei D. Mazor, Patrick J. Stiff, Gary J. Schiller
Journal: Blood
Blood (2023) 142 (Supplement 1): 6894.
https://doi.org/10.1182/blood-2023-181167
Published: 2023
Journal Articles

ALVR106, an Off-the-Shelf, Multivirus-Specific T-Cell Therapy, for the Treatment of Respiratory Viral Infections: Results from a Phase 1, First-in-Human, Dose-Ranging Trial

Free
Sarah Nikiforow, Mitchell Horwitz, John M. McCarty, Anum Abbas, James M. Coghill, Jenny Stanton, Julie Ma, Spyridoula Vasileiou, Sarah Gilmore, Bhagirathbhai Dholaria, Rabi Hanna, Randy Taplitz, Rajat Bansal
Journal: Blood
Blood (2023) 142 (Supplement 1): 6889.
https://doi.org/10.1182/blood-2023-189708
Published: 2023
Journal Articles

The DNA Sensor AIM2 Determines B Cell Fate after BCR Activation in Chronic Graft-Vs-Host Disease

Free
Fahmin Basher, Jonathan Visentin, Wei Jia, Jonathan C Poe, Christina Sofian, Hsuan Su, Sonali Bracken, Rachel Dicioccio, Itaevia Curry-Chisolm, Vincent T. Ho, Vanja Sisirak, Mitchell Horwitz, Nelson J. Chao, Stefanie Sarantopoulos
Journal: Blood
Blood (2023) 142 (Supplement 1): 2050.
https://doi.org/10.1182/blood-2023-188072
Published: 2023
Journal Articles

Ibrutinib Added to Standard Conditioning and As Consolidation Therapy Following Autologous Hematopoietic Stem Cell Transplantation (AutoHCT) for Relapsed/Refractory Activated-B-Cell Subtype Diffuse Large B-Cell Lymphoma (ABC-DLBCL): Primary Analysis of the US Intergroup Double-Blind Randomized Phase III Study Alliance A051301/BMT-CTN 1201

Free
Charalambos Andreadis, Olivia Bobek, Eric D. Hsi, Timothy S. Fenske, Susan M. Geyer, Patrick J. Stiff, Brian T. Hill, Mitchell Horwitz, Farhad Khimani, Richard F. Little, Shira N. Dinner, Jonathan W. Friedberg, Brad S. Kahl, Miguel-Angel Perales, Steven M. Devine, John P. Leonard, Nancy L. Bartlett
Journal: Blood
Blood (2023) 142 (Supplement 1): 437.
https://doi.org/10.1182/blood-2023-173742
Published: 2023
Journal Articles

Long-Term Outcomes after Unrelated Marrow Transplantation for Aplastic Anemia with Optimized Cyclophosphamide Dose (BMT CTN 0301)

Free
Mary Eapen, Joseph Antin, Jakub Tolar, Sally Arai, Mitchell Horwitz, Jainqun Kou, Eric Leifere, John M. McCarty, Ryotaro Nakamura, Michael A. Pulsipher, Mary M. Horowitz, H Joachim Deeg
Journal: Blood
Blood (2023) 142 (Supplement 1): 235.
https://doi.org/10.1182/blood-2023-178093
Published: 2023
Journal Articles

Fludarabine-Based Conditioning for Allogeneic Marrow Transplantation From Unrelated Donors in Severe Aplastic Anemia (SAA): Serious and Unexpected Adverse Events in Pre-Defined Cyclophosphamide (CY) Dose Levels

Free
Jakub Tolar, MD, PhD, H. Joachim Deeg, M.D., Sally Arai, MD, Mitchell Horwitz, MD, Joseph H. Antin, MD, John M. McCarty, MD, Roberta H. Adams, MD, Mary Eapen, MBBS, Marian Ewell, ScD, Eric Leifer, PhD, Iris Gersten, MS, Shelly L Carter, ScD, Mary M. Horowitz, MD, Dennis L Confer, MD, Ryotaro Nakamura, MD, Michael Pulsipher, MD, Nancy L DiFronzo, PhD, Paolo Anderlini, MD
Journal: Blood
Blood (2011) 118 (21): 3009.
https://doi.org/10.1182/blood.V118.21.3009.3009
Published: 2011
Journal Articles

Use of Aldehyde Dehydrogenase Content to Predict Dominating Cord in Double Cord Blood Transplant.

Free
Kristin M Page, MD, Tracy Gentry, Kevin Shoulars, PhD, Mitchell Horwitz, MD, Nicholas Herrmann, Norin Meadows, Brittney Philipps, Andrew Balber, PhD, Joanne Kurtzberg, MD
Journal: Blood
Blood (2009) 114 (22): 2155.
https://doi.org/10.1182/blood.V114.22.2155.2155
Published: 2009
Journal Articles

Long-Term Survival and Late Deaths After Hematopoietic Stem Cell Transplantation for Primary Immunodeficiency Diseases and Inborn Errors of Metabolism.

Free
Mary Eapen, MBBS, Kwang Woo Ahn, PhD, Paul Orchard, MD, Morton Jerome Cowan, MD, Stella M. Davies, MBBS, PhD, Anders Fasth, MD, PhD, Anna Hassebroek, MPH, Mouhab F. Ayas, MD, Carmem Bonfim, MD, Tracey O'Brien, Thomas Gross, MD, PhD, Mary M. Horowitz, MD, MS, Mitchell Horwitz, Edwin M. Horwitz, MD, PhD, Neena Kapoor, Joanne Kurtzberg, MD, Navneet S. Majhail, MD, MS, Olle Ringden, MD, Paul Szabolcs, MD, Paul A. Veys, MD, K. Scott Baker
Journal: Blood
Blood (2009) 114 (22): 3320.
https://doi.org/10.1182/blood.V114.22.3320.3320
Published: 2009
Journal Articles

Plerixafor and G-CSF versus placebo and G-CSF to mobilize hematopoietic stem cells for autologous stem cell transplantation in patients with multiple myeloma

Free
Clinical Trials & Observations
John F. DiPersio, Edward A. Stadtmauer, Auayporn Nademanee, Ivana N. M. Micallef, Patrick J. Stiff, Jonathan L. Kaufman, Richard T. Maziarz, Chitra Hosing, Stefan Früehauf, Mitchell Horwitz, Dennis Cooper, Gary Bridger, Gary Calandra, for the 3102 Investigators
Journal: Blood
Blood (2009) 113 (23): 5720–5726.
https://doi.org/10.1182/blood-2008-08-174946
Published: 2009
Journal Articles

Bortezomib Plus Melphalan and Prednisone as Induction Prior to Transplant or as Frontline Therapy for Non-Transplant Candidates in Patients with Previously Untreated Multiple Myeloma.

Free
Cristina Gasparetto, MD, Jon P Gockerman, Louis F Diehl, MD, Carlos de Castro, III, MD, Joseph O Moore, Gwynn D Long, Mitchell Horwitz, MD, John Chute, MD, Keith M Sullivan, MD, Rachel Neuwirth, Patricia H Davis, Linda M. Sutton, Russell D Anderson, Nelson Chao, David A. Rizzieri, MD
Journal: Blood
Blood (2008) 112 (11): 3325.
https://doi.org/10.1182/blood.V112.11.3325.3325
Published: 2008
Journal Articles

Safety Trial of NK Cell Enhanced Donor Lymphocyte Infusions from a 3-5/6 HLA Matched Family Member Following Nonmyeloablative Allogeneic Stem Cell Transplantation

Free
David A. Rizzieri, MD, Robert Storms, Ph.D, Daniel Nikcevich, MD, PhD, Bercedis Peterson, Ph.D, Debashish Misra, MD, Christine Apple, Megan Baker, Cristina Gasparetto, MD, Mitchell Horwitz, MD, John Chute, MD, Ashley Morris, PharmD., Nelson J. Chao, MD
Journal: Blood
Blood (2008) 112 (11): 342.
https://doi.org/10.1182/blood.V112.11.342.342
Published: 2008
Journal Articles

Total Body Irradiation 1350cGy/Fludarabine (TBI/FLU) vs Myeloablative Busulfan/Fludarabine (Bu/Flu) Preparation in Adult Recipients of Dual Umbilical Cord Blood (UCB) Transplantation: Superior Engraftment with Low Treatment-Related Mortality

Free
Mitchell Horwitz, MD, John Chute, MD, Cristina Gasparetto, MD, Gwynn Long, MD, David Rizzieri, MD, Keith Sullivan, MD, Jackie McPherson, Nelson Chao, MD
Journal: Blood
Blood (2008) 112 (11): 4403.
https://doi.org/10.1182/blood.V112.11.4403.4403
Published: 2008
Journal Articles

Myeloablative Intravenous Busulfan/Fludarabine Conditioning Does Not Facilitate Reliable Engraftment of Dual Umbilical Cord Blood Grafts in Adult Recipients.

Free
Mitchell Horwitz, MD, John Chute, MD, Cristina Gasparetto, MD, Gwynn Long, MD, David Rizzieri, MD, Ashley Morris, PharmD, Jackie McPherson, Keith Sullivan, MD, Nelson Chao, MD
Journal: Blood
Blood (2007) 110 (11): 2007.
https://doi.org/10.1182/blood.V110.11.2007.2007
Published: 2007