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Michael Kharas
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Journal Articles

Arginine methylation on MSI2 drives resistance to PRMT1/5 inhibitors in lymphoma, controls translation and dictates cell fate

Free
Chiara Evans, Sibasish Mohanty, Ingrid Erazo, Chi-Lam Poon, Eren Chu, Gerard Minuesa, Kathryn Chang, Emily Batchelor, Mandy Chan, Ersilia Barin, Sydney Bowker, Xuejing Yang, Zhuoning Li, Coraline Mlynarczyk, Mara Monetti, Elisa deStanchina, Yasuhide Furuta, Ari Melnick, Christina Leslie, Anas Younes, Ruslan Soldatov, Minkui Luo, Michael Kharas
Journal: Blood
Blood (2025) 146 (Supplement 1): 141.
https://doi.org/10.1182/blood-2025-141
Published: 2025
Journal Articles

Son maintains innate immune homeostasis in HSCs via splicing and retroelement control

Free
Hanzhi Luo, Mariela Cortés-López, Cyrus Tam, Angelika Aleman, Michael Xiao, Aspen Pierson, Rhoshini Raghuraman, Emily Batchelor, Quaid Morris, Dan Avi Landau, Erin Ahn, Michael Kharas
Journal: Blood
Blood (2025) 146 (Supplement 1): 210.
https://doi.org/10.1182/blood-2025-210
Published: 2025
Journal Articles

Investigating ribosome biogenesis in AML identifies MYB-binding protein 1A (MYBBP1A) as an essential regulator of leukemia cells

Free
Phuong To, Bertina Dragunaite, Pedro Casado, Quang-Anh Hoang, Emilie Alard, Lauren Harrison-Oakes, Anthony Velleca, Keith Woodley, Louie van de Lagemaat, Thomas Rohwetter, Alexandra Schurer, Mandy Chan, Salma Noorzai, Ly Vu, Alex Radzisheuskaya, Paolo Gallipoli, Ana Rio-Machin, Kamil Kranc, Faraz Mardakheh, Benjamin Towler, Pedro Cutillas, Michael Kharas, Diu Nguyen
Journal: Blood
Blood (2025) 146 (Supplement 1): 990.
https://doi.org/10.1182/blood-2025-990
Published: 2025
Journal Articles

A dual-receptor T-cell platform with Ab-TCR and costimulatory receptor achieves specificity and potency against AML

Free
Tao Dao, Guangyan Xiong, Sung Soo Mun, Jeremy Meyerberg, Tatyana Korontsvit, Jingyi Xiang, Ziyou Cui, Aaron Y. Chang, Casey Jarvis, Winson Cai, Hanzhi Luo, Aspen Pierson, Anthony Daniyan, Sarah Yoo, Sumiko Takao, Michael Kharas, Alex Kentsis, Cheng Liu, David A. Scheinberg
Journal: Blood
Blood (2024) 143 (6): 507–521.
https://doi.org/10.1182/blood.2023021054
Published: 2024
Includes: Supplemental data
Journal Articles

Ott1 (Rbm15) Is Required for the Large to Small Pre B-Cell Transition

Free
Michael Kharas, John Manis, MD, D. Gary Gilliland, MD, PhD, Glen D. Raffel, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 706.
https://doi.org/10.1182/blood.V112.11.706.706
Published: 2008