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Kathleen Sakamoto
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Journal Articles

Single-cell tracing of myeloid leukemia evolution in down syndrome reveals a latent progenitor bridging disease onset, progression and relapse

Free
Stephanie Frenz-Wiessner, Yue Wang, Katja Rohde, Giovanni Quinones-Valdez, Hasan Issa, José Gonçalves-Dias, Konstantin Schuschel, Paul Mack, Meng-Wei Ko, Yuanyuan Wang, Feiyang Ma, Kathleen Sakamoto, Vivian Chang, Xinshu Xiao, Jan-Henning Klusmann, Hanna Mikkola
Journal: Blood
Blood (2025) 146 (Supplement 1): 1472.
https://doi.org/10.1182/blood-2025-1472
Published: 2025
Journal Articles

Aberrant cell cycle regulation and osteoblastic differentiation in diamond-blackfan anemia (DBA) mesenchymal stem cells

Free
Hye Na Kim, Jacob Viduya, Jenny Youm, Kailen Mark, Lucy Liu, Fabian Suchy, Hiro Nakauchi, David Shyr, Anju Goyal, Bertil Glader, Joy Y. Wu, Kathleen Sakamoto
Journal: Blood
Blood (2025) 146 (Supplement 1): 747.
https://doi.org/10.1182/blood-2025-747
Published: 2025
Journal Articles

Small molecule OTS167 increases erythropoiesis and improves anemia in diamond blackfan anemia models in vitro and In Vivo

Free
Aya Shibuya, Kailen Mark, Ramesh Nair, Lucy Liu, Mark Wilkes, Anju Goyal, Kathleen Sakamoto
Journal: Blood
Blood (2025) 146 (Supplement 1): 3216.
https://doi.org/10.1182/blood-2025-3216
Published: 2025
Journal Articles

Immune Dysregulation and State-Transition Transcriptomic Signatures Underlying Pediatric Chronic Myeloid Leukemia Pathogenesis

Free
Tiffany Ybarra, David Frankhouser, Ryan Sathianathen, Minyoung Youn, Ramesh Nair, Ya-Huei Kuo, Guido Marcucci, Russell Rockne, Kathleen Sakamoto
Journal: Blood
Blood (2025) 146 (Supplement 1): 1982.
https://doi.org/10.1182/blood-2025-1982
Published: 2025
Journal Articles

Tumor-induced dendritic cell dysfunction impairs T-cell proliferation and confers poor prognosis in high-risk acute lymphoblastic leukemia

Free
Anil Kumar, Kory Hamane, Caroline Duault, Joao Rodrigues Lima-Junior, Da Hae Jung, Hanjun Qin, Sheyla Salcido, Min Huang, Xinying Guo, Adeleh Taghi Khani, Ashly Sanchez Ortiz, Lucy Ghoda, Guido Marcucci, Norman Lacayo, Kathleen Sakamoto, Christian Hurtz, Martin Carroll, Sarah Tasian, Huimin Geng, Lingyun Ji, Saro Armenian, Shai Izraeli, Holden Maecker, Xiwei Wu, Srividya Swaminathan
Journal: Blood
Blood (2025) 146 (Supplement 1): 5138.
https://doi.org/10.1182/blood-2025-5138
Published: 2025
Journal Articles

Loss of FoxM1 Promotes Erythroid Differentiation through Increased Proliferation of Erythroid Progenitors

Free
Minyoung Youn, PhD, Elena Bibikova, PhD, Corinne LaVasseur, BA, Bertil Glader, MD PhD, Kathleen Sakamoto, MD PhD, Anupama Narla, MD
Journal: Blood
Blood (2015) 126 (23): 933.
https://doi.org/10.1182/blood.V126.23.933.933
Published: 2015
Journal Articles

The Role of pp90rsk-Mediated CREB Phosphorylation in Acute Myelogenous Leukemia

Free
Bryan Mitton, MDPhD, Ritika Dutta, Yu-Chiao Hsu, MS, Kathleen Sakamoto, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2229.
https://doi.org/10.1182/blood.V124.21.2229.2229
Published: 2014
Journal Articles

CREB Regulates Cell Cycle Progression through RFC3-PCNA Axis in Acute Myeloid Leukemia

Free
Hee-Don Chae, PhD, Bryan Mitton, MDPhD, Kathleen Sakamoto, MD PhD
Journal: Blood
Blood (2014) 124 (21): 881.
https://doi.org/10.1182/blood.V124.21.881.881
Published: 2014
Journal Articles

RPS19 Deficiency Leads to GATA1 Downregulation through TNF-Mediated p38 MAPK Activation

Free
Minyoung Youn, Elena Bibikova, Nadia Danilova, Yukako Ono-Uruga, Yoan Konto-Ghiorghi, Rachel Ochoa, Anupama Narla, MD, Bertil Glader, Shuo Lin, Kathleen Sakamoto, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2934.
https://doi.org/10.1182/blood.V124.21.2934.2934
Published: 2014
Journal Articles

Transcriptional Profiling and Cytokine Signaling In The Pathogenesis Of Diamond-Blackfan Anemia

Free
Yoan Konto-Ghiorghi, Ph.D., Elena Bibikova, Bertil Glader, M.D., Ph.D, Anupama Narla, M.D., Kathleen Sakamoto
Journal: Blood
Blood (2013) 122 (21): 2474.
https://doi.org/10.1182/blood.V122.21.2474.2474
Published: 2013
Journal Articles

Defective Nucleotide Metabolism Contributes To p53 Activation In Diamond-Blackfan Anemia

Free
Nadia Danilova, Ph.D, Bibikova Elena, Todd Covey, David Nathanson, Elizabeth Dimitrova, Lindgren Anne, Bertil Glader, M.D., Ph.D, Caius Radu, Kathleen Sakamoto, Shuo Lin
Journal: Blood
Blood (2013) 122 (21): 1225.
https://doi.org/10.1182/blood.V122.21.1225.1225
Published: 2013
Journal Articles

Replication Factor C3 Is a Direct Target Of CREB, Promotes G1/S Transition Of Acute Myeloid Leukemia Cells, and Increases Hematopoietic Stem/Progenitor Cell Self-Renewal

Free
Hee-Don Chae, PhD, Kathleen Sakamoto
Journal: Blood
Blood (2013) 122 (21): 3754.
https://doi.org/10.1182/blood.V122.21.3754.3754
Published: 2013
Journal Articles

The pp90rsk-CREB Signaling Pathway Regulates Apoptosis In Acute Myelogenous Leukemia

Free
Bryan Mitton, MD, PhD, Ritika Dutta, Yu-Chiao Hsu, MS, Rachel Ochoa, Elliot Landaw, M.D., Ph.D., Xiangshu Xiao, Ph.D., Kathleen Sakamoto
Journal: Blood
Blood (2013) 122 (21): 3801.
https://doi.org/10.1182/blood.V122.21.3801.3801
Published: 2013
Journal Articles

Imbalance of p53 Family Members as a New Target of Therapeutics for Treatment of Diamond Blackfan Anemia.

Free
Nadia Danilova, PhD, Kathleen Sakamoto, M.D., Shuo Lin, Ph.D
Journal: Blood
Blood (2007) 110 (11): 423.
https://doi.org/10.1182/blood.V110.11.423.423
Published: 2007
Journal Articles

Identification of Meis1 as a Target of CREB in Myeloid Leukemogenesis.

Free
Samuel D. Esparza, MD, Deepa Shankar, Ph.D, Stanley Nelson, M.D., Kathleen Sakamoto, M.D., Ph.D
Journal: Blood
Blood (2006) 108 (11): 1945.
https://doi.org/10.1182/blood.V108.11.1945.1945
Published: 2006
Journal Articles

Acceleration of Leukemogenesis in CREB Transgenic Mice by Retroviral Insertional Mutagenesis.

Free
Salemiz Sandoval, BS, Kathleen Sakamoto, MD PHD, Shankar Deepa, PHD
Journal: Blood
Blood (2006) 108 (11): 4895.
https://doi.org/10.1182/blood.V108.11.4895.4895
Published: 2006