1-20 of 37
Karl-Johan Malmberg
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Ex vivo expanded adaptive NK cells in combination with a bispecific NK cell engager targeting BCMA for synergistic control of multiple myeloma

Free
Thorstein Boxaspen, Hannah Cuthbertson Husbyn, Kim Anh Giang, Caterina Heinz, Yumei Diao, Carina Norström, Kristina Witt-Mulder, Ellen Santangelo, Silje Zandstra Krokeide, Merete Thune Wiiger, Mari Suominen, Jenni Mäki-Jouppila, Fredrik Schjesvold, Per-Åke Nygren, Stefan Svensson Gelius, Ebba Sohlberg, Karl-Johan Malmberg
Journal: Blood
Blood (2025) 146 (Supplement 1): 2354.
https://doi.org/10.1182/blood-2025-2354
Published: 2025
Journal Articles

Targeting of tumor antigen CD38 and stress antigens MICA/B by CAR T cells provides a unique approach for the comprehensive treatment of multiple myeloma

Free
Soheila Shirinbak, Shilpi Chandra, Brian Groff, Samad Ibitokou, Spas Markov, John Reiser, Bryan Hancock, Tom Daily, Alma Gutierrez, Miguel Meza, Tom Lee, Betsy Rezner, Ramzey Abujarour, Raedun Clarke, John Goulding, Karl-Johan Malmberg, Maksim Mamonkin, Kai Wucherpfennig, Bahram Valamehr, Jode Goodridge, Alex Garcia, Martin Hosking
Journal: Blood
Blood (2025) 146 (Supplement 1): 2350.
https://doi.org/10.1182/blood-2025-2350
Published: 2025
Journal Articles

Development of next generation multi-antigen targeting off-the-shelf CAR T cells for conditioning-free treatment of B-cell lymphoma

Free
Shilpi Chandra, John Reiser, Brian Groff, Carissa Dege, Bryan Hancock, Alison O'Connor, Alma Gutierrez, Angela Gentile, Tom Lee, Ramzey Abujarour, Raedun Clarke, Betsy Rezner, John Goulding, Jode Goodridge, Karl-Johan Malmberg, Maksim Mamonkin, Bahram Valamehr, Alex Garcia, Martin Hosking
Journal: Blood
Blood (2025) 146 (Supplement 1): 4121.
https://doi.org/10.1182/blood-2025-4121
Published: 2025
Journal Articles

The development of FT839: An off-the-shelf CD19xCD38 dual-CAR T cell for the treatment of multiple myeloma

Free
Spas Markov, John Reiser, Brian Groff, Shilpi Chandra, Soheila Shirinbak, Carissa Dege, Bryan Hancock, Dan Lu, Alma Gutierrez, Angela Gentile, Tom Lee, Ramzey Abujarour, Betsy Rezner, John Goulding, Karl-Johan Malmberg, Maksim Mamonkin, Bahram Valamehr, Jode Goodridge, Martin Hosking, Alex Garcia
Journal: Blood
Blood (2025) 146 (Supplement 1): 7631.
https://doi.org/10.1182/blood-2025-7631
Published: 2025
Journal Articles

The development of an off-the-shelf CAR T-cell therapy co-targeting CD19 and CD38 for broad application in autoimmune disease

Free
Mark Jelcic, Daniel Morales-Mantilla, John Reiser, Brian Groff, Alma Gutierrez, Rina Ngalame, Alan Williams, Carissa Dege, Shilpi Chandra, Spas Markov, Soheila Shirinbak, Bjoern Gaertner, Mochtar Pribadi, Karina Palomares, Loraine Campanati, Amanda Yzaguirre, Stephanie Kennedy, Angela Macia, Alison O'Connor, Bryan Hancock, Pei-Fang Tsai, Ramzey Abujarour, Tom Lee, Raedun Clarke, Karl-Johan Malmberg, Maksim Mamonkin, Bahram Valamehr, Vaneet Sandhu, Alex Garcia, Martin Hosking, John Goulding, Jode Goodridge
Journal: Blood
Blood (2025) 146 (Supplement 1): 5895.
https://doi.org/10.1182/blood-2025-5895
Published: 2025
Journal Articles

Alloimmune Defense Receptor Combined with Genetic Ablation of Adhesion Ligand CD58 Is a Comprehensive Approach to Promote Functional Persistence of Allogeneic Cell Therapies without Conditioning Chemotherapy

Free
Alan Williams, Rina Mbofung, Daniel Morales-Mantilla, Brian Groff, Alison O'Connor, Binzhong Li, Ramesh Janani, Betsy Rezner, Mark Jelcic, Yijia Pan, Tom Lee, Karl-Johan Malmberg, Maksim Mamonkin, John Goulding, Jode Goodridge, Bahram Valamehr
Journal: Blood
Blood (2024) 144 (Supplement 1): 503.
https://doi.org/10.1182/blood-2024-210846
Published: 2024
Journal Articles

Affibody-Based BCMA x CD16 Dual Engagers for Activation of NK Cells Towards Multiple Myeloma

Free
Kim Anh Giang, Mizuha Kanaya, Thorstein Boxaspen, Minoru Kanaya, Silje Zandstra Krokeide, Yumei Diao, Fredrik Schjesvold, Fredrik Lehmann, Johan Nilvebrant, Stefan Svensson Gelius, Karl-Johan Malmberg, Per-Åke Nygren
Journal: Blood
Blood (2022) 140 (Supplement 1): 10699–10700.
https://doi.org/10.1182/blood-2022-164753
Published: 2022
Journal Articles

Combined Genetic Ablation of CD54 and CD58 in CAR Engineered Cytotoxic Lymphocytes Effectively Averts Allogeneic Immune Cell Rejection

Free
Quirin Hammer, Karlo Perica, Rina M Mbofung, Hanna van Ooijen, Erika Varady, Mark Jelcic, Yijia Pan, Pouria Momayyezi, Brian Groff, Ramzey Abujarour, Silje Zandstra Krokeide, Tom Lee, Alan M Williams, Jode P Goodridge, Bahram Valamehr, Bjorn Onfelt, Michel Sadelain, Karl-Johan Malmberg
Journal: Blood
Blood (2022) 140 (Supplement 1): 1165–1166.
https://doi.org/10.1182/blood-2022-163086
Published: 2022
Journal Articles

Perturbed NK-cell homeostasis associated with disease severity in chronic neutropenia

Free
Ebba Sohlberg, Aline Pfefferle, Eivind Heggernes Ask, Astrid Tschan-Plessl, Benedikt Jacobs, Herman Netskar, Susanne Lorenz, Minoru Kanaya, Mizuha Kosugi-Kanaya, Stephan Meinke, Anette Mörtberg, Petter Höglund, Mikael Sundin, Göran Carlsson, Jan Palmblad, Karl-Johan Malmberg
Journal: Blood
Blood (2022) 139 (5): 704–716.
https://doi.org/10.1182/blood.2021013233
Published: 2022
Includes: Supplemental data
Journal Articles

A Novel Stealth Strategy That Activates Adoptively Transferred Allogeneic Immune Cells and Avoids Rejection for Off-the-Shelf Cell-Based Cancer Therapy

Free
Alan M Williams, Ken Hayama, Yijia Pan, Brian Groff, Rina M Mbofung, Lauren Fong, Nicholas Brookhouser, Berhan Mandefro, Ramzey Abujarour, Tom Lee, Quirin Hammer, Karl-Johan Malmberg, Maksim Mamonkin, Ryan Bjordahl, Jode P Goodridge, Bahram Valamehr
Journal: Blood
Blood (2021) 138 (Supplement 1): 4800.
https://doi.org/10.1182/blood-2021-153614
Published: 2021
Journal Articles

KIR-HLA Interactions Lack Clinical Utility in Matched Unrelated Donor Transplantation for AML: An Analysis of the CIBMTR and DRST Registries

Free
Joshua A Fein, Roni Shouval, Elizabeth Krieger, Henning Baldauf, Katharina Fleischhauer, Nicolaus Kroeger, Mary M. Horowitz, Martin Maiers, Karl-Johan Malmberg, Jeffrey S. Miller, Mohamad Mohty, Arnon Nagler, Rizwan Romee, Johannes Schetelig, Stephen R. Spellman, Amir Ahmed Toor, Tao Wang, Daniel J. Weisdorf, John Koreth
Journal: Blood
Blood (2021) 138 (Supplement 1): 419.
https://doi.org/10.1182/blood-2021-149935
Published: 2021
Journal Articles

Off-the-Shelf, iPSC-Derived CAR-NK Cells Multiplexed-Engineered for the Avoidance of Allogeneic Host Immune Cell Rejection

Free
Rina M Mbofung, Alan M Williams, Ken Hayama, Yijia Pan, Brian Groff, Thomas Dailey, Sonia Reyes, Sajid Mahmood, Ketan Mathavan, Greg Bonello, Quirin Hammer, Karl-Johan Malmberg, Tom Lee, Ryan Bjordahl, Jode P Goodridge, Bahram Valamehr
Journal: Blood
Blood (2021) 138 (Supplement 1): 2795.
https://doi.org/10.1182/blood-2021-153484
Published: 2021
Journal Articles

Systems-Level Analysis of the Immune Repertoire in Neutropenia Reveal Arrested NK Cell Differentiation and Exhaustion

Free
Ebba Sohlberg, Aline Pfefferle, PhD, Eivind Heggernes Ask, MD, Astrid Tschan-Plessl, MD, Benedikt Jacobs, MD, Suzanne Lorenz, PhD, Stephan Meinke, Petter Hoglund, MD PhD, Mikael Sundin, MDPhD, Goran Karlsson, MDPhD, Jan Palmblad, MD PhD, Karl-Johan Malmberg, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 24–25.
https://doi.org/10.1182/blood-2020-141981
Published: 2020
Journal Articles

CAR19 iPSC-Derived NK Cells Utilize the Innate Functional Potential Mediated through NKG2A-Driven Education and Override the HLA-E Check Point to Effectively Target B Cell Lymphoma

Free
Minoru Kanaya, PhD, Camille Philippon, MSc, Artur Cieslar-Pobuda, PhD, Frank Cichocki, PhD, Michelle Saetersmoen, MSc, Sajid Mahmood, PhD, Quirin Hammer, PhD, Marianna Vincenti, MD, Merete Thune Wiiger, PhD, Hanna Julie Hoel, MSc, Lise Kveberg, PhD, Svetlana Gaidarova, MS, Ryan Bjordahl, PhD, Hui-yi Chu, PhD, Brian Groff, Matthew Denholtz, PhD, Jeffrey S. Miller, MD, Tom Lee, PhD, Dan S Kaufman, MDPhD, Jode P Goodridge, PhD, Bahram Valamehr, PhD, Karl-Johan Malmberg, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34–35.
https://doi.org/10.1182/blood-2020-138527
Published: 2020
Journal Articles

Innate-like Chemokine Receptor Profile and Migratory Behaviour By Terminally Differentiated and Educated NK Cells

Free
Mieszko Lachota, Daniel Alfredo Palacios, MSc, Dennis Clement, MSc, Eivind Heggernes Ask, MD, Hanna Julie Hoel, MSc, Merete Thune Wiiger, PhD, Marianna Vincenti, MD, Magdalena Winiarska, Radoslaw Zagozdzon, MD PhD, Karl-Johan Malmberg, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 24–25.
https://doi.org/10.1182/blood-2020-140944
Published: 2020
Journal Articles

FT576: Multi-Specific Off-the-Shelf CAR-NK Cell Therapy Engineered for Enhanced Persistence, Avoidance of Self-Fratricide and Optimized Mab Combination Therapy to Prevent Antigenic Escape and Elicit a Deep and Durable Response in Multiple Myeloma

Free
Jode P Goodridge, PhD, Ryan Bjordahl, PhD, Sajid Mahmood, PhD, John Reiser, PhD, Svetlana Gaidarova, MS, Robert Blum, MS, Frank Cichocki, PhD, Hui-yi Chu, PhD, Greg Bonello, PhD, Tom Lee, PhD, Brian Groff, Miguel Meza, BS, Yu-Waye Chu, MD, Bruce Walcheck, PhD, Karl-Johan Malmberg, MD PhD, Jeffrey S. Miller, MD, Armin Rehm, Uta Hopken, Bahram Valamehr, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 4–5.
https://doi.org/10.1182/blood-2020-142750
Published: 2020
Journal Articles

System-Level Disease-Driven Immune Signatures in Patients with Diffuse Large B-Cell Lymphoma Associated with Poor Survival

Free
Astrid Tschan-Plessl, MD, Eivind Heggernes Ask, Thea Johanne Gjerdingen, Michelle Saetersmoen, Hanna Julie Hoel, Merete Thune Wiiger, Msc, Johanna Olweus, Björn E Wahlin, MD PhD, Amir Horowitz, PhD, Todd A Fehniger, MD PhD, Harald Holte, MD PhD, Arne Kolstad, MD PhD, Karl-Johan Malmberg, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2897.
https://doi.org/10.1182/blood-2019-131359
Published: 2019
Journal Articles

FT538: Preclinical Development of an Off-the-Shelf Adoptive NK Cell Immunotherapy with Targeted Disruption of CD38 to Prevent Anti-CD38 Antibody-Mediated Fratricide and Enhance ADCC in Multiple Myeloma When Combined with Daratumumab

Free
Ryan Bjordahl, PhD, Svetlana Gaidarova, MS, Karrune Woan, MD PhD, Frank Cichocki, PhD, Greg Bonello, PhD, Megan Robinson, Chelsea Ruller, Mochtar Pribadi, PhD, Jason Dinella, PhD, Lauren Fong, PhD, Janel Huffman, MS, Hui-yi Chu, PhD, Tom Lee, PhD, Ramzey Abujarour, PhD, Dan S Kaufman, MD PhD, Karl-Johan Malmberg, MD PhD, Jeffrey S. Miller, MD, Bahram Valamehr, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 133.
https://doi.org/10.1182/blood-2019-131138
Published: 2019
Journal Articles

FT596: Translation of First-of-Kind Multi-Antigen Targeted Off-the-Shelf CAR-NK Cell with Engineered Persistence for the Treatment of B Cell Malignancies

Free
Jode P Goodridge, PhD, Sajid Mahmood, PhD, Huang Zhu, PhD, Svetlana Gaidarova, MS, Robert Blum, Ryan Bjordahl, PhD, Frank Cichocki, PhD, Hui-yi Chu, PhD, Greg Bonello, PhD, Tom Lee, PhD, Brian Groff, Miguel Meza, BS, Bruce Walcheck, PhD, Karl-Johan Malmberg, MD PhD, Jeffrey S. Miller, MD, Dan S Kaufman, MD PhD, Bahram Valamehr, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 301.
https://doi.org/10.1182/blood-2019-129319
Published: 2019
Journal Articles

Notch Activation Rescues Exhaustion in CISH -Deleted Human iPSC-Derived Natural Killer Cells to Promote In Vivo Persistence and Enhance Anti-Tumor Activity

Free
Huang Zhu, PhD, Robert Blum, Zhengming Wu, Andres Bahena, Hanna Julie Hoel, Eivind Heggernes Ask, Kun-Liang Guan, PhD, Karl-Johan Malmberg, MD PhD, Dan S Kaufman, MDPhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1279.
https://doi.org/10.1182/blood-2018-99-112791
Published: 2018