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Eleni Tholouli
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Journal Articles

An updated UK real-world analysis of factors affecting outcome following brexucabtagene autoleucel for relapsed or refractory adult acute lymphoblastic leukemia

Free
Anna Castleton, Michelle Lannon, Ned Atiyah, Alexandra Smith, Ahmed Abdulgawad, Mariam Amer, Farhan Anjum, Kathleen Cheok, David Burns, Richard Burt, Sridhar Chaganti, Johannes De Vos, Gerardo Errico, Adele Fielding, Lindsay George, Katharine Hodby, David Irvine, Shenbagaram Kasivisvanathan, Philippa Kelsey, Katja Kimberger, Andrew King, Anne-Louise Latif, David Marks, Navta Masand, Pierre McCarthy, Tobias Menne, Anthony Moorman, Nick Morley, Emma Nicholson, Maeve O'Reilly, Deborah Richardson, Huw Roddie, Clare Rowntree, Muhammad Saif, Thomas Seddon, Belen Sevillano, Kirsty Sharplin, Eleni Tholouli, Bela Patel Wrench, Deborah Yallop
Journal: Blood
Blood (2025) 146 (Supplement 1): 1565.
https://doi.org/10.1182/blood-2025-1565
Published: 2025
Journal Articles

Addition of thiotepa to a busulphan based conditioning regimen does not improve survival in patients allografted for acute myeloid leukaemia and myelodysplasia: Results of the UK impact cosi trial

Free
Charles Craddock, Graham Mcllroy, Hannah Vincent, Gabrielle Smith, Sarah Johnson, Rebecca Collings, Rebecca Faville, Vitor Jesus, Victoria Potter, Eleni Tholouli, Rachel Protheroe, Andrew Clark, Keith Wilson, Alexander Martin, Charles Crawley, Amy Publicover, Andrew Peniket, Anjum Khan, Jiri Pavlu, Patrick Medd, Jenny Byrne, Ronjon Chakraverty, Wendy Ingram, Andrea Bacigalupo, Alessandro Rambaldi, Aimee Jackson, Sylvie Freeman
Journal: Blood
Blood (2025) 146 (Supplement 1): 110.
https://doi.org/10.1182/blood-2025-110
Published: 2025
Journal Articles

Obecabtagene autoleucel (obe-cel), a CD19-targeting chimeric antigen receptor (CAR) T-cell therapy, in patients with severe, refractory systemic lupus erythematosus (SLE) in the Phase I CARLYSLE study: Initial safety, preliminary efficacy, pharmacokinetics, and biomarker results

Free
Claire Roddie, Maria Leandro, Ben Parker, Eleni Tholouli, David Jayne, Ben Uttenthal, Josefina Cortés-Hernández, Pere Barba, José Andrés Román Ivorra, Yanqing Hu, Wolfram Brugger, Silvia Basilico, Davide Germano, Ruth Pepper
Journal: Blood
Blood (2025) 146 (Supplement 1): 815.
https://doi.org/10.1182/blood-2025-815
Published: 2025
Journal Articles

Chimeric antigen receptor (CAR) T-cell persistence at month 3 predicts clinical outcomes in adult patients with relapsed/refractory B-cell acute lymphoblastic leukemia (R/R B-ALL) treated with obecabtagene autoleucel (obe-cel)

Free
Claire Roddie, Jae Park, Eleni Tholouli, Karamjeet Sandhu, Paul Shaughnessy, Pere Barba, Manuel Guerreiro, Deborah Yallop, Aaron Logan, Mehrdad Abedi, Pierre Lao-Sirieix, Ping Wang, Wolfram Brugger, Bijal Shah, Anthony Hunter, Daniel Deangelo, Elias Jabbour
Journal: Blood
Blood (2025) 146 (Supplement 1): 5118.
https://doi.org/10.1182/blood-2025-5118
Published: 2025
Journal Articles

A UK Intention to Treat Analysis of Brexucabtagene Autoleucel for Relapsed or Refractory Adult Acute Lymphoblastic Leukaemia Following 1 Year of Therapy Access

Free
Anna Z Castleton, Michelle Lannon, Ned Atiyah, Alexandra Smith, Lindsay George, Sridhar Chaganti, Eleni Tholouli, Pakhshan Farshi, Nicholas Cunningham, Claire Arnold, Nick Morley, Philippa Kelsey, Prudence Hardefeldt, Katja Kimberger, Manish Jain, Maeve O'Reilly, Richard Burt, Tobias Menne, Ahmed Abdulgawad, Katharine Hodby, Aniruddha Dayama, David A. Irvine, Anne Louise Latif, Deborah Susan Richardson, Mariam Amer, Ram Malladi, James Aries, Seda Cakmak, Johannes De Vos, Gerardo Errico, Emma Nicholson, Kirsty Marie Sharplin, Andrew Peniket, Bela Patel Wrench, Anthony Moorman, Clare Rowntree, David Marks, Adele Fielding, Deborah Yallop
Journal: Blood
Blood (2024) 144 (Supplement 1): 2823.
https://doi.org/10.1182/blood-2024-199287
Published: 2024
Journal Articles

Directionality of HLA-DP permissive mismatches improves risk prediction in HCT for acute leukemia and MDS

Free
Esteban Arrieta-Bolaños, Lars L. J. van der Burg, Tobias Gedde-Dahl, Marie Robin, Urpu Salmenniemi, Nicolaus Kröger, Ibrahim Yakoub-Agha, Anne Huynh, Charles Crawley, Eric Deconinck, Claude Eric Bulabois, Edouard Forcade, Eleni Tholouli, Joost G. K. van der Hem, Peter van Balen, Jorinde D. Hoogenboom, Liesbeth C. de Wreede, Florent Malard, Annalisa Ruggeri, Katharina Fleischhauer
Journal: Blood
Blood (2024) 144 (16): 1747–1751.
https://doi.org/10.1182/blood.2024024351
Published: 2024
Includes: Supplemental data
Journal Articles

Alternative donor transplantation for severe aplastic anemia: a comparative study of the SAAWP EBMT

Free
CME Clinical Trials & Observations
Juan Montoro, Dirk-Jan Eikema, Joe Tuffnell, Victoria Potter, Krzysztof Kalwak, Constantijn J. M. Halkes, Alexander Kulagin, Matthew Collin, Robert F. Wynn, Stephen Robinson, Emma Nicholson, Henrik Sengeloev, Jennifer Clay, Khalid Halahleh, Elena Skorobogatova, Jaime Sanz, Jakob Passweg, Stephan Mielke, Samppa Ryhänen, Ben Carpenter, Tobias Gedde-Dahl, Eleni Tholouli, Renato Fanin, Philippe Lewalle, Austin Kulasekararaj, Antonio Risitano, Régis Peffault de Latour
Journal: Blood
Blood (2024) 144 (3): 323–333.
https://doi.org/10.1182/blood.2024024173
Published: 2024
Journal Articles

The UK Impact Transplant Trials Network: An Effective National Strategy to Accelerate the Delivery of Randomized Trials in Stem Cell Transplantation

Free
Charles Craddock, David Marks, Victoria Potter, Wendy A Ingram, Rebecca Collings, Eleni Tholouli, Rachel Protheroe, Hugh Allen, Alex Ross, Dawn Farrar, Shamyla Siddique, Rebecca Bishop, Ronjon Chakraverty
Journal: Blood
Blood (2023) 142 (Supplement 1): 5097.
https://doi.org/10.1182/blood-2023-188490
Published: 2023
Journal Articles

Obecabtagene Autoleucel (obe-cel, AUTO1) for Relapsed/Refractory Adult B-cell Acute Lymphoblastic Leukemia (R/R B-ALL): Pooled Analysis of the Ongoing FELIX Phase Ib/II Study

Free
Claire Roddie, Karamjeet S. Sandhu, Eleni Tholouli, Paul Shaughnessy, Pere Barba, Manuel Guerreiro, Michael R. Bishop, Jean A. Yared, Armin Ghobadi, Deborah Yallop, Aaron C. Logan, Amer M. Beitinjaneh, Jeremy M. Pantin, Martha Arellano, Sridhar Chaganti, Ram Malladi, Tobias Menne, Virginia Escamilla Gómez, Katharine Hodby, Krishna Gundabolu, Luke Mountjoy, Kristen M. O'Dwyer, Sameem Abedin, Hassan Alkhateeb, Bijal D. Shah, Pierre Lao-Sirieix, Gianfranco Pittari, Kapil Saxena, Yiyun Zhang, Wolfram Brugger, Martin A. Pule, Jae H. Park, Daniel J. DeAngelo, Elias Jabbour
Journal: Blood
Blood (2023) 142 (Supplement 1): 222.
https://doi.org/10.1182/blood-2023-179454
Published: 2023
Journal Articles

Transplant Outcomes for Acute Myeloid Leukemia or Myelodysplastic Syndromes Secondary to Acquired Aplastic Anemia or Paroxysmal Nocturnal Hemoglobinuria: A Report from the EBMT Severe Aplastic Anemia Working Party

Free
Pedro H. Prata, Dirk-Jan Eikema, Sr., Brian Piepenbroek, Austin Kulasekararaj, Beatrice Drexler, Jennifer Tjon, Krista Vaht, Mahmoud Aljurf, Patrice Chevallier, Tobias Gedde-Dahl, Ain Kaare, Uwe Platzbecker, Urpu Salmenniemi, Thomas Schroeder, Jenny Louise Byrne, Denis Guyotat, Nicolaus Kröger, Fiorenza Barraco, Johan Maertens, Eleni Tholouli, Didier Blaise, Simona Sica, Jürgen Finke, Antonio M Risitano, Regis Peffault De Latour
Journal: Blood
Blood (2023) 142 (Supplement 1): 704.
https://doi.org/10.1182/blood-2023-184783
Published: 2023
Journal Articles

Alternative Donor Transplantation for Severe Aplastic Anemia: A Comparative Study of the Saawp EBMT

Free
Juan Montoro, Dirk-Jan Eikema, Sr., Joe Tuffnell, Sr., Victoria Potter, Krzysztof Kalwak, Sr., Stijn Halkes, Sr., Aleksandr Kulagin, Sr., Matthew P. Collin, Sr., Robert Wynn, Sr., Stephen Robinson, Jr., Emma Nicholson, Sr., Henrik Sengeloev, Jennifer Clay, Sr., Khaled Halahleh, Sr., Elena Skorobogatova, Sr., Jakob Passweg, Sr., Stephan Mielke, Samppa Ryhanen, Sr., Ben Carpenter, Tobias Gedde-Dahl, Eleni Tholouli, Renato Fanin, Philippe Lewalle, Sr., Austin Kulasekararaj, Antonio M Risitano, Regis Peffault De Latour
Journal: Blood
Blood (2023) 142 (Supplement 1): 1047.
https://doi.org/10.1182/blood-2023-174724
Published: 2023
Journal Articles

Long-Term Efficacy and Safety of Obecabtagene Autoleucel (obe-cel) in Adult Patients (pts) with Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia ([R/R B-ALL]; Pooled Analysis from ALLCAR19 and FELIX Phase Ib Studies) or Other B-cell Malignancies (ALLCAR19 Extension Study)

Free
Claire Roddie, Eleni Tholouli, Paul Shaughnessy, Elias Jabbour, Aaron C. Logan, Katharine Hodby, Luke Mountjoy, Adrian John Clifton Bloor, David Irvine, David C. Linch, Kim H. Orchard, William Wilson, Bilyana Popova, Juliana Dias, Giulia Agliardi, Victoria Spanswick, Helen Lowe, Marina Mitsikakou, Eftychia Charalambous, Joanna Dawes, Meera Raymond, Yanqing Hu, Wolfram Brugger, Martin A. Pule, Jae H. Park, Karl Peggs
Journal: Blood
Blood (2023) 142 (Supplement 1): 2114.
https://doi.org/10.1182/blood-2023-180666
Published: 2023
Journal Articles

HLA Class I Mismatches Reduce Survival after HCT in the Ptcy Era: A Study By the EBMT Cellular Therapy and Immunobiology Working Party

Free
Esteban Arrieta-Bolanos, Edouard F. Bonneville, Marie Robin, Tobias Gedde-Dahl, Urpu Salmenniemi, Nicolaus Kröger, Ibrahim Yakoub-Agha, Charles Crawley, Goda Choi, Annoek E. C. Broers, Edouard Forcade, Martin Carre, Xavier Poiré, Anne Huynh, Péter Reményi, Stig Lenhoff, Fabio Ciceri, Eleni Tholouli, Thomas Schröder, Eric Deconinck, Kristina Elisabet Carlson, Liesbeth C. de Wreede, Jorinde D. Hoogenboom, Florent Malard, Annalisa Ruggeri, Katharina Fleischhauer
Journal: Blood
Blood (2023) 142 (Supplement 1): 2178.
https://doi.org/10.1182/blood-2023-185945
Published: 2023
Journal Articles

Should the European Leukemia Net 2022 Adverse Risk Classification of NPM1 mutated Acute Myeloid Leukemia be Revisited? Among Adverse Risk Cytogenetics, Solely Complex Karyotype Is Associated with Worse Post-Transplant Survival: A Study from the EBMT Acute Leukemia Working Party

Free
Nour Moukalled, Myriam Labopin, Jurjen Versluis, Gerard Socié, Didier Blaise, Urpu Salmenniemi, Alessandro Rambaldi, Tobias Gedde-Dahl, Eleni Tholouli, Nicolaus Kröger, Jean-Henri Bourhis, Peter A. Von Dem Borne, Etienne Daguindau, Édouard Forcade, Arnon Nagler, Jordi Esteve, Fabio Ciceri, Ali Bazarbachi, Mohamad Mohty
Journal: Blood
Blood (2023) 142 (Supplement 1): 4987.
https://doi.org/10.1182/blood-2023-185434
Published: 2023
Journal Articles

Dual targeting of CD19 and CD22 with bicistronic CAR-T cells in patients with relapsed/refractory large B-cell lymphoma

Free
Clinical Trials & Observations
Claire Roddie, Lazaros J. Lekakis, Maria A. V. Marzolini, Aravind Ramakrishnan, Yiyun Zhang, Yanqing Hu, Vijay G. R. Peddareddigari, Nushmia Khokhar, Robert Chen, Silvia Basilico, Meera Raymond, Frederick Arce Vargas, Kevin Duffy, Wolfram Brugger, Maeve A. O’Reilly, Leigh Wood, David C. Linch, Karl S. Peggs, Carlos Bachier, Elizabeth Lihua Budde, Connie Lee Batlevi, Nancy Bartlett, David Irvine, Eleni Tholouli, Wendy Osborne, Kirit M. Ardeshna, Martin A. Pule
Journal: Blood
Blood (2023) 141 (20): 2470–2482.
https://doi.org/10.1182/blood.2022018598
Published: 2023
Includes: Supplemental data
Journal Articles

First in Human Study of AUTO4, a TRBC1-Targeting CAR T-Cell Therapy in Relapsed/Refractory TRBC1-Positive Peripheral T-Cell Lymphoma

Free
Kate Cwynarski, Gloria Iacoboni, Eleni Tholouli, Tobias F. Menne, David A. Irvine, Nivetha Balasubramaniam, Leigh Wood, Justin Shang, Yiyun Zhang, Silvia Basilico, Birgit Huber, Mary Vinson, Koki Lilova, Wolfram Brugger, Martin Pule
Journal: Blood
Blood (2022) 140 (Supplement 1): 10316–10317.
https://doi.org/10.1182/blood-2022-165971
Published: 2022
Journal Articles

Comparison of Fludarabine/Melphalan (FluMel) with Fludarabine/Melphalan/BCNU or Thiotepa (FBM/FTM) in Patients with AML in First Complete Remission Undergoing Allogeneic Hematopoietic Stem Cell Transplantation - a Registry Study on Behalf of the EBMT Acute Leukemia Working Party

Free
Jesus Duque Afonso, Jürgen Finke, Maud Ngoya, Jacques-Emmanuel Galimard, Charles Craddock, Kavita Raj, Adrian Bloor, Emma Nicholson, Matthias Eder, Kim H. Orchard, Thomas Valerius, John A. Snowden, Eleni Tholouli, Charles Crawley, Matthew P. Collin, Keith Wilson, Alain Gadisseur, Rachel Elizabeth Protheroe, Eva Maria Wagner, Bipin Savani, Alexandros Spyridonidis, Fabio Ciceri, Arnon Nagler, Mohamad Mohty
Journal: Blood
Blood (2022) 140 (Supplement 1): 2110–2112.
https://doi.org/10.1182/blood-2022-162277
Published: 2022
Journal Articles

Post-Transplant MRD Status and T Cell Chimerism Predict Outcomes in Patients Allografted for AML/MDS-a Prospective Analysis from the UK NCRI Figaro Trial

Free
(Justin) Ching Ting Loke, Nicholas McCarthy, Aimee E Jackson, Shamyla Siddique, Andrea Hodgkinson, John Mason, Charles Crawley, Maria H Gilleece, Andy Peniket, Rachel Elizabeth Protheroe, Rahuman Salim, Eleni Tholouli, Keith Wilson, Georgia M. Andrew, Richard Dillon, Naeem Khan, Victoria Potter, Pramila Krishnamurthy, Charles Craddock, Sylvie D Freeman
Journal: Blood
Blood (2021) 138 (Supplement 1): 415.
https://doi.org/10.1182/blood-2021-149269
Published: 2021
Journal Articles

CAR-T Toxicity Management and Steroid Use in High-Grade B-Cell Lymphoma: Impact on Real-World Survival Outcomes in the UK

Free
Robin Sanderson, Andrea Kuhnl, Eleni Tholouli, Tobias F Menne, Amit Patel, Sridhar Chaganti, Caroline Besley, Emma Nicholson, Anne-Louise Latif, Ceri Jones, Lourdes Rubio, Charlotte Stenson, Amrith Mathew, Kirsty Sharplin, Jessica Bazin, Lorna Neill, Kathleen Pao Lynn Cheok, Katarzyna Aleksandra Aleksandra Jalowiec, Claire Roddie, Maeve A O'Reilly
Journal: Blood
Blood (2021) 138 (Supplement 1): 531.
https://doi.org/10.1182/blood-2021-149501
Published: 2021
Journal Articles

COVID-19 Infection of HSCT Recipients Is Associated with High Mortality but No Detectable Cytokine Storm at Presentation

Free
Giovanna Lucchini, Elena Cozma, Aimee Jackson, Kimberly Gilmour, Rachel Elizabeth Protheroe, Eleni Tholouli, Robert F Wynn, Keith Wilson, Karl S Peggs, Victoria Potter, Anne Parker, Charles Craddock, Shankara Paneesha, Emma Nicholson, David I. Marks, Oana Mirci-Danicar, Christopher Parrish, Alexander M Martin, Graham McIlroy, Rebecca Bishop, Rebecca Collings, Ellie Williams, Persis J Amrolia
Journal: Blood
Blood (2021) 138 (Supplement 1): 1788.
https://doi.org/10.1182/blood-2021-146515
Published: 2021